Issue 39, 2013
From the journal:

Chemical Communications

A gold(iii) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells†‡

Ching Tung Lum,a   Alice Sze-Tsai Wong,b   Marie CM Lin,c   Chi-Ming Che*a  and  Raymond Wai-Yin Sun*a  

* Corresponding authors

a Department of Chemistry, State Key Laboratory of Synthetic Chemistry, and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong
E-mail: rwysun@hku.hk; cmche@hku.hk
Fax: +852-28592154

b School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong

c Division of Neurosurgery, Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong

Abstract

A cytotoxic gold(III) complex of meso-tetraphenylporphyrin ([Au(TPP)]Cl, denoted gold-1a) blocks the self-renewal ability of cancer stem-like cells and shows appealing safety pharmacological profiles in rodents.

Graphical abstract: A gold(iii) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC37366A
Article type
Communication
Submitted
09 10月 2012
Accepted
15 11月 2012
First published
16 11月 2012

Chem. Commun., 2013,49, 4364-4366

Permissions

Request permissions

A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

C. T. Lum, A. S. Wong, M. C. Lin, C. Che and R. W. Sun, Chem. Commun., 2013, 49, 4364 DOI: 10.1039/C2CC37366A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements