Issue 15, 2020
From the journal:

Analyst

A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection†

K. Sudhakara Prasad, ORCID logo ‡a   Yousef Abugalyon,a   Chunqiang Li,b   Feng Xu ORCID logo c  and  XiuJun Li ORCID logo *ad  

* Corresponding authors

a Department of Chemistry, University of Texas at El Paso, 500 West University Avenue, El Paso, Texas, USA
E-mail: xli4@utep.edu
Fax: +1-915-747-5748
Tel: +1-915-747-8967

b Department of Physics, Border Biomedical Research Center, University of Texas at El Paso, 500 West University Avenue, El Paso, Texas, USA

c Bioinspired Engineering & Biomechanics Center (BEBC), Xi'an Jiaotong University, Shaanxi, P. R. China

d Biomedical Engineering, Border Biomedical Research Center, and Environmental Science & Engineering, University of Texas at El Paso, USA

Abstract

A low-cost, sensitive, and disposable paper-based immunosensor for instrument-free colorimetric detection of pancreatic cancer biomarker PEAK1 was reported for the first time by capitalizing the catalytic properties of gold nanoparticles in colour dye degradation. This simple signal amplification method enhances the detection sensitivity by about 10 fold.

Graphical abstract: A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection

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Supplementary files

Article information

DOI
https://doi.org/10.1039/D0AN00704H
Article type
Communication
Submitted
08 4月 2020
Accepted
08 6月 2020
First published
17 6月 2020

Analyst, 2020,145, 5113-5117

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A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection

K. S. Prasad, Y. Abugalyon, C. Li, F. Xu and X. Li, Analyst, 2020, 145, 5113 DOI: 10.1039/D0AN00704H

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