Issue 91, 2017
From the journal:

Chemical Communications

Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery†

Joan Mayol-Llinàs, ORCID logo a   William Farnaby‡b  and  Adam Nelson ORCID logo *ac  

* Corresponding authors

a School of Chemistry, University of Leeds, UK
E-mail: a.s.nelson@leeds.ac.uk

b Takeda Cambridge, Unit 418, Cambridge Science Park, Milton Road, Cambridge, UK

c Astbury Centre for Structural Molecular Biology, University of Leeds, UK

Abstract

A modular synthetic approach was developed that yielded thirty diverse lead-like scaffolds suitable for CNS drug discovery.

Graphical abstract: Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

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Article information

DOI
https://doi.org/10.1039/C7CC06078E
Article type
Communication
Submitted
03 8月 2017
Accepted
20 9月 2017
First published
03 11月 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 12345-12348

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Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

J. Mayol-Llinàs, W. Farnaby and A. Nelson, Chem. Commun., 2017, 53, 12345 DOI: 10.1039/C7CC06078E

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