Issue 10, 2017
From the journal:

Chemical Communications

PSMA-targeted contrast agents for intraoperative imaging of prostate cancer†,‡

Kai Bao,ab   Jeong Heon Lee,a   Homan Kang,a   G. Kate Park,a   Georges El Fakhria  and  Hak Soo Choi ORCID logo *a  

* Corresponding authors

a Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, MA 02114, USA
E-mail: hchoi12@mgh.harvard.edu
Fax: +1 617-643-2604
Tel: +1 617-726-5784

b Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China

Abstract

Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist.

Graphical abstract: PSMA-targeted contrast agents for intraoperative imaging of prostate cancer,

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Article information

DOI
https://doi.org/10.1039/C6CC09781B
Article type
Communication
Submitted
13 12月 2016
Accepted
09 1月 2017
First published
13 1月 2017

Chem. Commun., 2017,53, 1611-1614

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PSMA-targeted contrast agents for intraoperative imaging of prostate cancer,

K. Bao, J. H. Lee, H. Kang, G. K. Park, G. El Fakhri and H. S. Choi, Chem. Commun., 2017, 53, 1611 DOI: 10.1039/C6CC09781B

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