Issue 1, 2010
From the journal:

Chemical Communications

Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

Richard J. Payne*a  and  Chi-Huey Wongbc  

* Corresponding authors

a School of Chemistry, The University of Sydney, Sydney, Australia
E-mail: payne@chem.usyd.edu.au
Fax: +61 2 9351 3329
Tel: +61 2 9351 5877

b President, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, Taiwan
E-mail: chwong@gate.sinica.edu.tw
Fax: +886 2 2785 3852
Tel: +886 2 2789 9400

c Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, USA
E-mail: wong@scripps.edu

Abstract

A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.

Graphical abstract: Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

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Article information

DOI
https://doi.org/10.1039/B913845E
Article type
Feature Article
Submitted
14 Jul 2009
Accepted
08 Sep 2009
First published
30 Oct 2009

Chem. Commun., 2010,46, 21-43

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Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

R. J. Payne and C. Wong, Chem. Commun., 2010, 46, 21 DOI: 10.1039/B913845E

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