Issue 3, 2024

Superhydrophobic nanosized metal–organic framework composites for the targeted removal of hydrophobic pharmaceuticals with outstanding bacterial anti-adhesion properties

Abstract

The increasing concentration of pharmaceutical waste after the COVID-19 pandemic has accelerated the urgency of removing various drugs from environmental water specimens. Realizing this concern, herein, a nanosized superhydrophobic metal–organic framework (SH-MOF) material was synthesized and its activated form (SH-MOF′) was used for the selective removal of two widely used drugs, i.e., favipiravir (a potential COVID-19 drug) and diflunisal. The reusable MOF has very high adsorption capacities towards favipiravir and difunisal i.e., 86.5 and 148 mg g−1, respectively, within 5 min. The MOF also adsorbs drug molecules in highly acidic and alkaline media with almost equal efficiency. The porous nano-sized MOF shows high selectivity towards the adsorption of favipiravir and difunisal over the common ions and hydrophilic drugs. To make the adsorption process more user-friendly, a MOF-coated sponge composite was developed and utilized for filtration-based drug separation. Moreover, the superhydrophobic MOF and silver nanoparticle-coated cotton composite was fabricated which displayed excellent bacterial anti-adhesion and anti-bacterial properties towards Staphylococcus aureus bacteria.

Graphical abstract: Superhydrophobic nanosized metal–organic framework composites for the targeted removal of hydrophobic pharmaceuticals with outstanding bacterial anti-adhesion properties

Supplementary files

Article information

Article type
Paper
Submitted
19 10月 2023
Accepted
18 1月 2024
First published
23 1月 2024

Environ. Sci.: Nano, 2024,11, 1233-1244

Superhydrophobic nanosized metal–organic framework composites for the targeted removal of hydrophobic pharmaceuticals with outstanding bacterial anti-adhesion properties

S. Ghosh, A. Rana, A. Patel, D. Manna and S. Biswas, Environ. Sci.: Nano, 2024, 11, 1233 DOI: 10.1039/D3EN00747B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements