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Revealing the Monooxygenase Mechanism for Selective Ring Cleavage of Anthraquinone by BTG13 through Multiscale Simulations

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ChemBioChem, 2025, 26
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Mechanistic Analysis of Stereodivergent Nitroalkane Cyclopropanation Catalyzed by Nonheme Iron Enzymes

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Modifications of Prenyl Side Chains in Natural Product Biosynthesis

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Characterization and employment of novel α-ketoglutarate dependent oxygenases for efficient synthesis of antifungal alkyl citrates

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Unraveling the Mechanism of the Oxidative C–C Bond Coupling Reaction Catalyzed by Deoxypodophyllotoxin Synthase

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Search for Inhibitors against Inflammatory Responses of Microglia in a Meroterpenoid Library Constructed by Synthetic–Biological Manipulation of Biosynthetic Pathways

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Coordination dynamics of iron enables the selective C–N coupling but bypasses unwanted C–H hydroxylation in Fe(II)/α-ketoglutarate- dependent non-heme enzymes

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Structure-Guided Engineering of 2-Oxoglutarate-Dependent Oxygenases: Principles, Case Studies, and Emerging Opportunities

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Engineering the Reaction Pathway of a Non-heme Iron Oxygenase Using Ancestral Sequence Reconstruction

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Biosynthesis of Meroterpenoid Furanasperterpenes: Enzymatic Insights into a 6/6/6/6/5 Pentacyclic Skeleton

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The phenol-2-monooxygenase FgPhm1 regulates DON synthesis, pathogenicity and environmental stress response in Fusarium graminearum

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Selective Oxidation of Tertiary C–H Bonds in Steroids Catalyzed by the Heterodimeric Fe(II)/α-Ketoglutarate-Dependent Oxygenase TlxI–J

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Biosynthesis and Assembly Logic of Fungal Hybrid Terpenoid Natural Products

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Current Advances in the Enzyme Engineering of O2‐Dependent Enzymes – Boosting the Versatility and Applicability of Oxygenases and Oxidases

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Structure–function and mechanistic analyses of nickel-dependent sulfonamide synthase

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Modifications of Prenyl Side Chains in Natural Product Biosynthesis

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Deciphering Deoxynybomycin Biosynthesis Reveals Fe(II)/α-Ketoglutarate-Dependent Dioxygenase-Catalyzed Oxazoline Ring Formation and Decomposition

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Structural and Mechanistic Basis for Orthoester Formation by αKG-Free Endoperoxide Isomerase in Novofumigatonin Biosynthesis

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Engineered and total biosynthesis of fungal specialized metabolites

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Mechanistic Insights into the CC Desaturation Catalyzed by an Fe(II) and αKG‐Dependent Oxygenase AndA

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An Alternative Mechanism for C–C Desaturation Underscores a Dual-Controlled Mechanism for the Fate of Radical Intermediate in Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenase DfmD

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Natural and Engineered Regioselective O-Demethylation with Enantioselective Substrate Recognition by Fe(II)/2-Oxoglutarate-Dependent Oxygenases in Corydalmine Biosynthesis

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Harnessing Fe(II)/α-ketoglutarate-dependent oxygenases for sustainable synthesis

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Recent developments in the engineered biosynthesis of fungal meroterpenoids

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Enzymatic formation of endoperoxide by Fe(II)/α-KG-dependent dioxygenase NvfI: Insight into substrate-assisted activation of the distant C–H bond and incorporation of two oxygen molecules

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