Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor

Kohei Ohshiro; Yui Sasaki; Qi Zhou; Xiaojun Lyu; Yusuke Yamanashi; Katsumasa Nakahara; Hirokazu Nagaoka; Tsuyoshi Minami

doi:10.1039/D1AN02188E

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Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor†

Kohei Ohshiro,

^a Yui Sasaki,

^a Qi Zhou,

^a Xiaojun Lyu,

^a Yusuke Yamanashi,^b Katsumasa Nakahara,^b Hirokazu Nagaoka^b and Tsuyoshi Minami

*^a

Author affiliations

* Corresponding authors

^a Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, Japan
E-mail: tminami@iis.u-tokyo.ac.jp

^b JNC Petrochemical Corp., 5-1, Goikaigan, Ichihara, Chiba, Japan

Abstract

Herein, we report an extended-gate-type organic field-effect transistor (OFET) sensor for oxytocin. The fabricated OFET-based immunosensor has successfully detected oxytocin at a ppt level in human saliva with high recovery rates (96–102%). We believe our sensor would pave the way for the realization of portable sensors for healthcare monitoring.

This article is part of the themed collection: Analyst HOT Articles 2022

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Article information

DOI: https://doi.org/10.1039/D1AN02188E
Article type: Communication
Submitted: 03 ⴷⵓⵊ 2021
Accepted: 15 ⴱⵕⴰ 2022
First published: 16 ⴱⵕⴰ 2022

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Analyst, 2022,147, 1055-1059

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Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor

K. Ohshiro, Y. Sasaki, Q. Zhou, X. Lyu, Y. Yamanashi, K. Nakahara, H. Nagaoka and T. Minami, Analyst, 2022, 147, 1055 DOI: 10.1039/D1AN02188E

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Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor†

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Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor

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