Issue 19, 2018

Lipid metabolism in inflammation-related diseases

Abstract

There are thousands of lipid species existing in cells, which belong to eight different categories. Lipids are the essential building blocks of cells. Recent studies have started to unveil the important functions of lipids in regulating cell metabolism. However, we are still at a very early stage in fully understanding the physiological and pathological functions of lipids. The application of lipidomics for studying lipid metabolism can provide a direct readout of the cellular status and broadens our understanding of the mechanisms that underpin metabolic disease states. This review provides an introduction to lipid metabolism and its role in modulating homeostasis and immunity. We also describe representative applications of lipidomics for studying lipid metabolism in inflammation-related diseases.

Graphical abstract: Lipid metabolism in inflammation-related diseases

Article information

Article type
Minireview
Submitted
06 ⵢⵓⵏ 2018
Accepted
24 ⵢⵓⵍ 2018
First published
21 ⵖⵓⵛ 2018

Analyst, 2018,143, 4526-4536

Lipid metabolism in inflammation-related diseases

C. Zhang, K. Wang, L. Yang, R. Liu, Y. Chu, X. Qin, P. Yang and H. Yu, Analyst, 2018, 143, 4526 DOI: 10.1039/C8AN01046C

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