Issue 3, 2015

Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

Abstract

In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic–hydrophilic balance with respect to transition temperatures.

Graphical abstract: Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

Supplementary files

Article information

Article type
Paper
Submitted
15 ⴽⵜⵓ 2014
Accepted
03 ⵏⵓⵡ 2014
First published
03 ⵏⵓⵡ 2014

Org. Biomol. Chem., 2015,13, 783-792

Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

R. Xu, F. Ali-Rachedi, N. M. Xavier, S. Chambert, F. Ferkous, Y. Queneau, S. J. Cowling, E. J. Davis and J. W. Goodby, Org. Biomol. Chem., 2015, 13, 783 DOI: 10.1039/C4OB02191F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements