Gas-phase oxidative dehydrogenation of long chain alkenols for the production of key fragrance ingredients: from Rosalva isomers to Costenal analogues

Abstract

The continuous-flow, gas-phase oxidative dehydrogenation (ODH) of an actual mixture of decen-1-ol isomers (“Isorosalva” alcohol) towards the corresponding mixture of aldehydes (“Costenal” analogues, valuable ingredients in perfumes formulation) is herein reported for the first time over noble metal-free catalysts. In particular, the optimisation of the reaction conditions over a copper ferrite (Cu/Fe/O), as well as dedicated characterizations and comparisons between the fresh, the post-reaction (reduced) and regenerated (re-oxidised) catalytic material, allowed us to underline the key role of well dispersed copper oxide over a Fe-enriched spinel in promoting the selective ODH of Isorosalva alcohol. The superior catalytic activity and selectivity of CuO/γ-Fe₂O₃ synthesized ad hoc were attributed to the very high dispersion of Cu over the support as well as to a cooperative effect between Cu and Fe species in promoting the redox cycle.