Issue 15, 2022

Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells

Abstract

Highly sensitive and reliable PEC detection of miRNAs still faces some challenges like the inaccuracy caused by coexisting interferences in the PEC system. Herein, we developed a split-type “turn-off” PEC biosensor based on spatially-extended 3D magnetic DNA nanodevices with high-order DNA amplifiers for sensitive detection of miRNAs in cancer cells.

Graphical abstract: Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
26 ⵉⴱⵔ 2022
Accepted
01 ⵢⵓⵏ 2022
First published
10 ⵢⵓⵏ 2022

Analyst, 2022,147, 3415-3419

Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells

H. Yuan, J. Sun, Q. Zhang, M. Chu, G. Cheng, X. Li and Q. Xue, Analyst, 2022, 147, 3415 DOI: 10.1039/D2AN00712F

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