PhI(OAc)2-mediated intramolecular oxidative C–N coupling and detosylative aromatization: an access to indolo[2,3-b]quinolines

Quan-Bing Wang; Shi Tang; Ying-Jie Wang; Yue Yuan; Tieqiao Chen; Ai-Qun Jia

doi:10.1039/D1RA01894A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

PhI(OAc)₂-mediated intramolecular oxidative C–N coupling and detosylative aromatization: an access to indolo[2,3-b]quinolines†

Quan-Bing Wang,‡^a Shi Tang,‡*^a Ying-Jie Wang,^a Yue Yuan,^a Tieqiao Chen

^a and Ai-Qun Jia

*^a

Author affiliations

* Corresponding authors

^a School of Life and Pharmaceutical Sciences, Key Laboratory of Tropical Biological Resources of Ministry of Education, Hainan University, Haikou, China
E-mail: tangshi705@163.com, ajia@hainanu.edu.cn

Abstract

A PIDA mediated intramolecular oxidative C–N coupling and subsequent detosylative aromatization to afford indolo[2,3-b]quinoline derivatives has been developed. This tandem reaction provided an efficient method for the synthesis of valuable indolo[2,3-b]quinoline derivatives.

This article is part of the themed collection: Elegant Synthetic Routes to Indole Derivatives

Download options Please wait...

Supplementary files

Supplementary information PDF (3555K)

Article information

DOI: https://doi.org/10.1039/D1RA01894A
Article type: Paper
Submitted: 10 ⵎⴰⵕ 2021
Accepted: 20 ⵉⴱⵔ 2021
First published: 10 ⵎⴰⵢ 2021
This article is Open Access

Download Citation

RSC Adv., 2021,11, 17206-17211

Permissions

Request permissions

PhI(OAc)₂-mediated intramolecular oxidative C–N coupling and detosylative aromatization: an access to indolo[2,3-b]quinolines

Q. Wang, S. Tang, Y. Wang, Y. Yuan, T. Chen and A. Jia, RSC Adv., 2021, 11, 17206 DOI: 10.1039/D1RA01894A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Social activity

Fetching data from CrossRef.
This may take some time to load.

RSC Advances