Issue 21, 2021

Detection of the effect of polydopamine (PDA)-coated polydimethylsiloxane (PDMS) substrates on the release of H2O2 from a single HeLa cell

Abstract

Endogenous H2O2 generated by a single HeLa cell that was adhered on the PDA-coated PDMS substrates under 25 mM glucose culture conditions was detected using a home-built photoelectric dual detection platform. With PMA as the stimulus, the cell released a small amount of H2O2 and its mitochondrial membrane potential (MMP) decrease was smaller, compared with that on the PDMS substrates.

Graphical abstract: Detection of the effect of polydopamine (PDA)-coated polydimethylsiloxane (PDMS) substrates on the release of H2O2 from a single HeLa cell

Supplementary files

Article information

Article type
Communication
Submitted
19 ⵖⵓⵛ 2021
Accepted
07 ⵛⵓⵜ 2021
First published
08 ⵛⵓⵜ 2021

Analyst, 2021,146, 6445-6449

Detection of the effect of polydopamine (PDA)-coated polydimethylsiloxane (PDMS) substrates on the release of H2O2 from a single HeLa cell

J. Xiao, M. Tian, L. Su, Y. Bao, L. Niu and X. Zhang, Analyst, 2021, 146, 6445 DOI: 10.1039/D1AN01506K

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