Issue 8, 2020

An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery

Abstract

A multifunctional chemical neural probe fabrication process exploiting PDMS thin-film transfer to incorporate a microfluidic channel onto a silicon-based microelectrode array (MEA) platform, and enzyme microstamping to provide multi-analyte detection is described. The Si/PDMS hybrid chemtrode, modified with a nano-based on-probe IrOx reference electrode, was validated in brain phantoms and in rat brain.

Graphical abstract: An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery

Supplementary files

Article information

Article type
Communication
Submitted
07 ⵉⵏⵏ 2020
Accepted
18 ⵎⴰⵕ 2020
First published
20 ⵎⴰⵕ 2020

Lab Chip, 2020,20, 1390-1397

An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery

B. Wang, X. Wen, Y. Cao, S. Huang, H. A. Lam, T. “. Liu, P. Chung, H. G. Monbouquette, P. Chiou and N. T. Maidment, Lab Chip, 2020, 20, 1390 DOI: 10.1039/D0LC00021C

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