Asymmetric cobalt catalysts for hydroboration of 1,1-disubstituted alkenes†
Abstract
Chiral iminopyridine oxazoline (IPO) ligands were designed, synthesized and utilized for the first cobalt-catalyzed highly regio- and enantioselective anti-Markovnikov hydroboration of 1,1-disubstituted aryl alkenes. These novel IPO ligands will likely be of high value for asymmetric transformations with first-row transition metals.
- This article is part of the themed collection: HOT articles in Organic Chemistry Frontiers for 2014