Issue 4, 2018

Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

Abstract

A cobalt-catalyzed cross-dehydrogenative coupling of 2-arylimidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant is reported. A broad range of 2-arylimidazo[1,2-a]pyridines reacted smoothly to afford the corresponding products in moderate to good yields. The advantages of this method are: inexpensive catalysts, environmentally benign conditions and operational convenience.

Graphical abstract: Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

Supplementary files

Article information

Article type
Research Article
Submitted
26 ⵛⵓⵜ 2017
Accepted
24 ⴽⵜⵓ 2017
First published
26 ⴽⵜⵓ 2017

Org. Chem. Front., 2018,5, 577-581

Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

Q. Yang, S. Li and J. (. Wang, Org. Chem. Front., 2018, 5, 577 DOI: 10.1039/C7QO00875A

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