Issue 74, 2016

Highly selective intramolecular addition of C–N and S–N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

Abstract

Palladium-catalyzed highly selective intramolecular addition of C–N and S–N bonds to alkynes has been achieved, and two distinct functional indoles were synthesized rapidly from the same set of substrates in a catalyst-controlled manner. This protocol features high atom economy, moderate to high yields and excellent selectivity, thus affording a practical approach to functional indoles.

Graphical abstract: Highly selective intramolecular addition of C–N and S–N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

Supplementary files

Article information

Article type
Paper
Submitted
20 ⵢⵓⵏ 2016
Accepted
18 ⵢⵓⵍ 2016
First published
18 ⵢⵓⵍ 2016

RSC Adv., 2016,6, 70682-70690

Highly selective intramolecular addition of C–N and S–N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

C. Wu, F. Zhao, Y. Du, L. Zhao, L. Chen, J. Wang and H. Liu, RSC Adv., 2016, 6, 70682 DOI: 10.1039/C6RA15945A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements