Issue 53, 2016

Rh(iii)-catalyzed C–H oxidative ortho-olefination of arenes using 7-azaindole as a directing group and utilization in the construction of new tetracyclic heterocycles containing a 7-azaindole skeleton

Abstract

A Rh(III)-catalyzed C–H ortho-mono-olefination of aryls directed by 7-azaindoles was reported. This method opens up a novel pathway to synthesize complex 7-azaindole derivatives and interestingly, we observed an intramolecular cascade annulation via unexpected double directing groups (7-azaindole and carbonyl).

Graphical abstract: Rh(iii)-catalyzed C–H oxidative ortho-olefination of arenes using 7-azaindole as a directing group and utilization in the construction of new tetracyclic heterocycles containing a 7-azaindole skeleton

Supplementary files

Article information

Article type
Paper
Submitted
22 ⵎⴰⵕ 2016
Accepted
12 ⵎⴰⵢ 2016
First published
12 ⵎⴰⵢ 2016

RSC Adv., 2016,6, 48205-48211

Rh(III)-catalyzed C–H oxidative ortho-olefination of arenes using 7-azaindole as a directing group and utilization in the construction of new tetracyclic heterocycles containing a 7-azaindole skeleton

B. Liu, R. Li, W. Zhan, X. Wang, Z. Ge and R. Li, RSC Adv., 2016, 6, 48205 DOI: 10.1039/C6RA07478B

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