Issue 25, 2015

One-pot synthesis of doxorubicin-loaded multiresponsive nanogels based on hyperbranched polyglycerol

Abstract

Doxorubicin-loaded nanogels with multiresponsive properties are prepared using hyperbranched polyglycerol as a biocompatible scaffold. The nanogels are synthesized in a single step combining free-radical polymerization and a mild nanoprecipitation technique. The nanogels respond to different biological stimuli such as low pH and reductive environments, resulting in a more efficient cell proliferation inhibition in A549 cells.

Graphical abstract: One-pot synthesis of doxorubicin-loaded multiresponsive nanogels based on hyperbranched polyglycerol

Supplementary files

Article information

Article type
Communication
Submitted
22 ⵉⵏⵏ 2015
Accepted
02 ⵎⴰⵕ 2015
First published
02 ⵎⴰⵕ 2015

Chem. Commun., 2015,51, 5264-5267

Author version available

One-pot synthesis of doxorubicin-loaded multiresponsive nanogels based on hyperbranched polyglycerol

A. Sousa-Herves, S. Wedepohl and M. Calderón, Chem. Commun., 2015, 51, 5264 DOI: 10.1039/C5CC00644A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements