Issue 13, 2014

Frontier microfluidic techniques for short and long-term single cell analysis

Abstract

Here, we review the frontier microfluidic techniques for single cell analysis (SCA), which is important for research of many biological systems. Microfluidics provides high-throughput, high-resolution experiments at low cost and reagent use, making it especially useful for single cell analysis. Recent advancements in the field have made SCA more feasible, improving device throughput and resolution, adding capabilities, and combining different functions to bring forth new assays. Developments in incubation have allowed for long-term cell tracking assays to be performed with single cell resolution. The ability of systems to provide chemical isolation or prolonged growth of adherent cells is also discussed.

Graphical abstract: Frontier microfluidic techniques for short and long-term single cell analysis

Article information

Article type
Frontier
Submitted
05 ⵉⵏⵏ 2014
Accepted
17 ⴱⵕⴰ 2014
First published
17 ⴱⵕⴰ 2014

Lab Chip, 2014,14, 2161-2167

Author version available

Frontier microfluidic techniques for short and long-term single cell analysis

J. Avesar, T. B. Arye and S. Levenberg, Lab Chip, 2014, 14, 2161 DOI: 10.1039/C4LC00013G

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