A 3D millifluidic model of a dermal perivascular microenvironment on a chip

Chiara Martinelli, Alberto Bocconi, Sofia Milone, Teresa Baldissera, Leonardo Cherubin, Giovanni Buccioli, Simone Perottoni, Claudio Conci, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Emanuela Jacchetti and Manuela Teresa Raimondi

Lab Chip, 2025, 25, 423
DOI: 10.1039/D4LC00898G

Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures

Johannes Dornhof, Jochen Kieninger, Harshini Muralidharan, Jochen Maurer, Gerald A. Urban and Andreas Weltin

Lab Chip, 2022, 22, 225
DOI: 10.1039/D1LC00689D

An assessment of the response of human MSCs to hydrostatic pressure in environments supportive of differential chondrogenesis

Farhad Chariyev-Prinz, Alex Szojka, Nuno Neto, Ross Burdis, Michael G. Monaghan and Daniel J. Kelly

Journal of Biomechanics, 2023, 154, 111590
DOI: 10.1016/j.jbiomech.2023.111590

Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation

Federica Rey, Letizia Messa, Erika Maghraby, Giovanna Casili, Sara Ottolenghi, Bianca Barzaghini, Manuela Teresa Raimondi, Cristina Cereda, Salvatore Cuzzocrea, Gianvincenzo Zuccotti, Emanuela Esposito, Irene Paterniti and Stephana Carelli

Antioxidants & Redox Signaling, 2023, 38, 160
DOI: 10.1089/ars.2022.0046

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

Margarida Barroso, Michael G. Monaghan, Raluca Niesner and Ruslan I. Dmitriev

Advanced Drug Delivery Reviews, 2023, 201, 115081
DOI: 10.1016/j.addr.2023.115081

Non-invasive classification of macrophage polarisation by 2P-FLIM and machine learning

Nuno GB Neto, Sinead A O'Rourke, Mimi Zhang, Hannah K Fitzgerald, Aisling Dunne and Michael G Monaghan

eLife, 2022, 11
DOI: 10.7554/eLife.77373

Time-Dependent Anabolic Response of hMSC-Derived Cartilage Grafts to Hydrostatic Pressure

Farhad Chariyev-Prinz, Nuno Neto, Michael G. Monaghan, Daniel J. Kelly and Catherine K. Kuo

Journal of Tissue Engineering and Regenerative Medicine, 2023, 2023, 1
DOI: 10.1155/2023/9976121

Balance between the cell viability and death in 3D

Angela C. Debruyne, Irina A. Okkelman and Ruslan I. Dmitriev

Seminars in Cell & Developmental Biology, 2023, 144, 55
DOI: 10.1016/j.semcdb.2022.09.005

Global Literature Analysis of Organoid and Organ‐on‐Chip Research

Jun‐ya Shoji, Richard P. Davis, Christine L. Mummery and Stefan Krauss

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202301067

From Organ-on-a-Chip to Human-on-a-Chip: A Review of Research Progress and Latest Applications

Yisha Huang, Tong Liu, Qi Huang and Yuxi Wang

ACS Sens., 2024, 9, 3466
DOI: 10.1021/acssensors.4c00004

Cholesterol crystals drive metabolic reprogramming and M1 macrophage polarisation in primary human macrophages

Sinead A. O'Rourke, Nuno G.B. Neto, Eimear Devilly, Lianne C. Shanley, Hannah K. Fitzgerald, Michael G. Monaghan and Aisling Dunne

Atherosclerosis, 2022, 352, 35
DOI: 10.1016/j.atherosclerosis.2022.05.015

A quantitative meta-analysis comparing cell models in perfused organ on a chip with static cell cultures

Martin Dufva

Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-35043-5

Fundamental Neurochemistry Review: Microglial immunometabolism in traumatic brain injury

Nathan R. Strogulski, Luis V. Portela, Brian M. Polster and David J. Loane

Journal of Neurochemistry, 2023, 167, 129
DOI: 10.1111/jnc.15959

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Nuno G. B. Neto, Meenakshi Suku, David A. Hoey and Michael G. Monaghan

Stem Cell Res Ther, 2023, 14
DOI: 10.1186/s13287-023-03606-y

Luminescence lifetime imaging of three-dimensional biological objects

Ruslan I. Dmitriev, Xavier Intes and Margarida M. Barroso

Journal of Cell Science, 2021, 134, 1
DOI: 10.1242/jcs.254763

Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

Mostafa Azimzadeh, Patricia Khashayar, Meitham Amereh, Nishat Tasnim, Mina Hoorfar and Mohsen Akbari

Biosensors, 2021, 12, 6
DOI: 10.3390/bios12010006

Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis

Achilleas Floudas, Nuno Neto, Carl Orr, Mary Canavan, Phil Gallagher, Conor Hurson, Michael G Monaghan, Sunil Nagpar, Ronan H Mullan, Douglas J Veale and Ursula Fearon

Annals of the Rheumatic Diseases, 2022, 81, 193
DOI: 10.1136/annrheumdis-2021-220458

Non-invasive label-free imaging analysis pipeline for in situ characterization of 3D brain organoids

Caroline E. Serafini, Seleipiri Charles, Paloma Casteleiro Costa, Weibo Niu, Brian Cheng, Zhexing Wen, Hang Lu and Francisco E. Robles

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-72038-2

Emerging microfluidics for bioreactor

Hanxu Chen, Yile Fang, Zhiqiang Luo, Yu Wang, Weijian Sun and Yuanjin Zhao

Materials Today, 2025, 86, 356
DOI: 10.1016/j.mattod.2025.03.009

Sensors-integrated organ-on-a-chip for biomedical applications

Hanxu Chen, Zhiqiang Luo, Xiang Lin, Yujuan Zhu and Yuanjin Zhao

Nano Res., 2023, 16, 10072
DOI: 10.1007/s12274-023-5651-9

Integrated Electrochemical and Optical Biosensing in Organs‐on‐Chip

Pratik Tawade and Massimo Mastrangeli

ChemBioChem, 2024, 25
DOI: 10.1002/cbic.202300560

A Systematic Review on Organ-on-a-Chip in PDMS or Hydrogel in Dentistry: An Update of the Literature

Tania Vanessa Pierfelice, Emira D’Amico, Morena Petrini, Mario Romano, Camillo D’Arcangelo, Ludovico Sbordone, Antonio Barone, Roberto Plebani and Giovanna Iezzi

Gels, 2024, 10, 102
DOI: 10.3390/gels10020102