Jing Zhou, Quanquan Zhou and Jie-Ping Wan
Org. Biomol. Chem., 2024,22, 8065-8077
Abstract
Recent advances in the multicomponent synthesis of pyrazoles have been reviewed. The reactions involving hydrazine, hydrazine, diazo compound, and nitrile/amine as N![[double bond, length as m-dash]](https://www.rsc.org/images/entities/char_e001.gif)
N donors are summarized.
Wan-Jie Wei, Yan-Qing Zeng, Xian-Feng Liang, Fei-Hu Cui, Mao-Rui Wang, Ying-Ming Pan, Wen-Gui Duan and Hai-Tao Tang
Green Chem., 2025,27, 1006-1012
Abstract
We have developed a mild and efficient electrochemical reduction approach employing aryl diazonium salts as dual synthons to synthesize valuable multi-substituted pyrazoles for the first time.
Song Cheng, Wen Gu, Kun Zhao, Shu Ting Zhang, Lan Yang, Qing Song Liu, Xiao Xiao Li and Zhi Gang Zhao
New J. Chem., 2023,47, 19698-19708
Abstract
Synthesis of iodine-substituted allylic pyrazoles through NIS-mediated regioselective addition of allenamides with pyrazoles.
Yan He, Hua Sun, Guo-Hui Liu, Ying-Chun Wang and Ying-Ming Pan
Org. Chem. Front., 2024,11, 7078-7084
Abstract
A strategy for preparing a series of thiomethyl/selenomethyl substituted pyrazoles through palladium-catalyzed isocyanide insertion into the C(sp)–S bond, followed by TMSN3-involved CuI/Sc(OTf)3 catalyzed intermolecular cyclization was reported.
Yu Zhang, Qiannan Li, Zhimin Hu, Zhiyong Leng, Wei-dong Zhang and Shoubhik Das
Chem. Soc. Rev., 2026, Advance Article
Abstract
A conceptual overview and discussions are presented to showcase the synthesis of five-membered heteroaromatics and related drugs using emerging toolboxes (photochemical synthesis, electrocatalysis and biocatalysis).