Tracking of lineage mass via quantitative phase imaging and confinement in low refractive index microwells

Jingzhou Zhang, Justin Griffin, Koushik Roy, Alexander Hoffmann and Thomas A. Zangle

Lab Chip, 2024, 24, 4440
DOI: 10.1039/D4LC00389F

Non-invasive detection of bladder cancer via microfluidic immunoassay of the protein biomarker NMP22

Xiali Guan, Da Lu, Zhigang Chen, Zhuya Wang, Gang Zhou and Yubo Fan

Anal. Methods, 2023, 15, 3275
DOI: 10.1039/D3AY00664F

Elevating single-particle encapsulation in droplet microfluidics by utilizing surface acoustic wave and flow control

Chunhua He, Huasheng Zhuo, Canfeng Yang, Jianxin Wang, Xian Jiang, Fan Li, Chengxu Lin, Hai Yang, Tuying Yong, Xiangliang Yang, Zhiyong Liu, Yan Ma, Lei Nie, Guanglan Liao and Tielin Shi

Lab Chip, 2025, 25, 2669
DOI: 10.1039/D4LC00787E

Demystifying EV heterogeneity: emerging microfluidic technologies for isolation and multiplexed profiling of extracellular vesicles

Guihua Zhang, Xiaodan Huang, Sinong Liu, Yiling Xu, Nan Wang, Chaoyong Yang and Zhi Zhu

Lab Chip, 2025, 25, 1228
DOI: 10.1039/D4LC00777H

Advancing in situ single-cell microbiological analysis through a microwell droplet array with a gradual open sidewall

Jie Wang, Lin Du, Yuwei Han, Dawei Zhang and Dalei Jing

Lab Chip, 2023, 23, 5165
DOI: 10.1039/D3LC00590A

Pillar Array Mixer for Postcolumn Derivatization Integrated into Liquid Chromatography-Based Microfluidic Device

Muneki Isokawa, Kanki Nakanishi, Takahiro Kanamori, Tetsushi Sekiguchi, Takashi Funatsu, Shuichi Shoji and Makoto Tsunoda

Anal. Chem., 2024, 96, 11002
DOI: 10.1021/acs.analchem.4c01669

Recent Advances in Microfluidics-Based Monitoring of Waterborne Pathogens: From Isolation to Detection

Guohao Xu, Gaozhe Cai, Lijuan Liang, Jianxin Cheng, Lujie Song, Rui Sun, Feng Shen, Bo Liu, Shilun Feng and Jin Zhang

Micromachines, 2025, 16, 462
DOI: 10.3390/mi16040462

Using single cell technologies to understand HIV latency models

Julia S. Huff and Edward P. Browne

Current Opinion in HIV and AIDS, 2025, 20, 488
DOI: 10.1097/COH.0000000000000959

Digital PCR for Single-Cell Analysis

Weibo Fang, Xudong Liu, Mariam Maiga, Wenjian Cao, Ying Mu, Qiang Yan and Qiangyuan Zhu

Biosensors, 2024, 14, 64
DOI: 10.3390/bios14020064

On-Chip Droplet Splitting with High Volume Ratios Using a 3D Conical Microstructure-Based Microfluidic Device

Jian Yu, Xueqing Kan, Zhaoyang Xiang, Jiachen Liu, Fubing Bao and Likai Hou

Langmuir, 2024, 40, 22355
DOI: 10.1021/acs.langmuir.4c03047

Microfluidic design in single-cell sequencing and application to cancer precision medicine

Xin Han, Xing Xu, Chaoyang Yang and Guozhen Liu

Cell Reports Methods, 2023, 3, 100591
DOI: 10.1016/j.crmeth.2023.100591

An Inclined Push–Pull Probe for In Situ Cell Staining and Calcium Channel Activation

Xiaohong Hu, Huan Luo, Nahoko Kasai, Hizuru Nakajima, Shungo Kato, Katsumi Uchiyama and Sifeng Mao

Anal. Chem., 2025, 97, 15376
DOI: 10.1021/acs.analchem.5c02265

Harnessing the Manipulation of Single Cells to Construct Biological Structures: Tools and Applications

Congying Liu, Yuhe Chen, Rui Tong, Ziyang Wang, Deyuan Zhang, Huawei Chen and Pengfei Zhang

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202316357

Advanced Microfluidics for Single Cell‐Based Cancer Research

Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela and Miguel Xavier

Advanced Science, 2025
DOI: 10.1002/advs.202500975

Intelligent microscopic imaging system based on microwell array chip for high-throughput analysis of single-cell heterogeneity

Lingzhi Ye, Rui Deng, Aiping Zhi, Duo Sun, Wei Ye, Shi Hu, Tingting Zhan, Rui Hao, Xi Chen, Bin Sun, Chunyan Liu, Lin Dang, Meng Li, Zebin Chen, Lin Zeng, Jienan Shen, Xiangmeng Qu and Hui Yang

Microchemical Journal, 2025, 211, 113136
DOI: 10.1016/j.microc.2025.113136

A facile single-cell patterning strategy based on harbor-like microwell microfluidics

Yingnan Sun, Yongshu Liu, Dezhi Sun, Kexin Liu, Yuyan Li, Yumin Liu and Shusheng Zhang

Biomed. Mater., 2024, 19, 045018
DOI: 10.1088/1748-605X/ad4e83

Microfluidic single‐cell technologies for immunotherapeutic target discovery: From design concepts to preclinical applications

Haopu Wang, Kangfu Chen and Zongjie Wang

VIEW, 2025
DOI: 10.1002/VIW.20250065

Microchannel Chip Based on Fluid Dynamics Control for Cell Analysis and Manipulation

Jiao Hua, Zhiwei Fan, Chong Ji, Dongyang Miao, Chaobo Huang and Ranhua Xiong

Adv Funct Materials, 2025
DOI: 10.1002/adfm.202514148

High-Throughput Microfluidic Electroporation (HTME): A Scalable, 384-Well Platform for Multiplexed Cell Engineering

William R. Gaillard, Jess Sustarich, Yuerong Li, David N. Carruthers, Kshitiz Gupta, Yan Liang, Rita Kuo, Stephen Tan, Sam Yoder, Paul D. Adams, Hector Garcia Martin, Nathan J. Hillson and Anup K. Singh

Bioengineering, 2025, 12, 788
DOI: 10.3390/bioengineering12080788

Application and outlook of electrochemical technology in single-cell analysis

Ke Huang, Yi Han Wang, Hao Zhang, Ting Ya Wang, Xiao Hui Liu, Liu Liu, Hui Jiang and Xue Mei Wang

Biosensors and Bioelectronics, 2023, 242, 115741
DOI: 10.1016/j.bios.2023.115741

A Capillary-Force-Driven, Single-Cell Transfer Method for Studying Rare Cells

Jacob Amontree, Kangfu Chen, Jose Varillas and Z. Hugh Fan

Bioengineering, 2024, 11, 542
DOI: 10.3390/bioengineering11060542

Investigation of Microparticle Displacement and Control Near the Triple Contact Line of an Evaporating Droplet

Gwanghyeon Yu, Wonhyung Lee and Hojin Kim

KSMPE, 2025, 24, 69
DOI: 10.14775/ksmpe.2025.24.3.069

A review of innovative electrochemical strategies for bioactive molecule detection and cell imaging: Current advances and challenges

Hao Zhang, Hui Jiang, Xiaohui Liu and Xuemei Wang

Analytica Chimica Acta, 2024, 1285, 341920
DOI: 10.1016/j.aca.2023.341920

Two-layered microwell-array device for preparation of single-neuron culture samples

Ayaka Nakama and Takashi Yasuda

J. Micromech. Microeng., 2024, 34, 085011
DOI: 10.1088/1361-6439/ad5b00