Applications of alkyl orthoesters as valuable substrates in organic transformations, focusing on reaction media

Zahra Khademi and Kobra Nikoofar

RSC Adv., 2020, 10, 30314
DOI: 10.1039/D0RA05276K

Self-delivery nanoparticles of an amphiphilic irinotecan–enediyne conjugate for cancer combination chemotherapy

Jing Li, Baojun Li, Lili Sun, Bing Duan, Shuai Huang, Yuan Yuan, Yun Ding and Aiguo Hu

J. Mater. Chem. B, 2019, 7, 103
DOI: 10.1039/C8TB02367K

An acyclic enediyne with a furyl tethering group for efficient inhibition of tumor cell viability

Depeng Song, Yu Tian, Shuai Huang, Baojun Li, Yuan Yuan and Aiguo Hu

J. Mater. Chem. B, 2015, 3, 8584
DOI: 10.1039/C5TB01867F

Direct functionalization of cyclic ethers with maleimide iodides via free radial-mediated sp3 C–H activation

Xiaoyu Cheng, Baojun Li, Mengsi Zhang, Haotian Lu, Wenbo Wang, Yun Ding and Aiguo Hu

Chem. Commun., 2021, 57, 4787
DOI: 10.1039/D1CC01484F

Rigidochromism by imide functionalisation of an aminomaleimide fluorophore

Jonathan T. Husband, Yujie Xie, Thomas R. Wilks, Louise Male, Miquel Torrent-Sucarrat, Vasilios G. Stavros and Rachel K. O'Reilly

Chem. Sci., 2021, 12, 10550
DOI: 10.1039/D1SC03307G

Synthesis of maleimide-based enediynes with cyclopropane moieties for enhanced cytotoxicity under normoxic and hypoxic conditions

Wenbo Wang, Haotian Lu, Mengsi Zhang, Hailong Ma, Xiaoyu Cheng, Yun Ding and Aiguo Hu

J. Mater. Chem. B, 2021, 9, 4502
DOI: 10.1039/D1TB00142F

Facilitating Myers–Saito cyclization through acid-triggered tautomerization for the development of maleimide-based antitumor agents

Haotian Lu, Hailong Ma, Baojun Li, Mengsi Zhang, Huimin Chen, Yue Wang, Xinxin Li, Yun Ding and Aiguo Hu

J. Mater. Chem. B, 2020, 8, 1971
DOI: 10.1039/C9TB02589H

Synthesis and biological properties of maleimide-based macrocyclic lactone enediynes

Xiaoxuan Li, Haotian Lu, Mingming Ji, Ke Sun, Fangxu Pu, Yun Ding and Aiguo Hu

Org. Biomol. Chem., 2022, 20, 5481
DOI: 10.1039/D2OB00571A

Enediyne as π linker in D–π–A dyes for dye-sensitized solar cells

Youfu Wang, Luhua Dong, Zhiwei Zheng, Xing Li, Rulin Xiong, Jianli Hua and Aiguo Hu

RSC Adv., 2016, 6, 12124
DOI: 10.1039/C5RA25938J

Oxaenediynes through the Nicholas‐Type Macrocyclization Approach

Anna G. Lyapunova, Natalia A. Danilkina, Alexander F. Khlebnikov, Beate Köberle, Stefan Bräse and Irina A. Balova

Eur J Org Chem, 2016, 2016, 4842
DOI: 10.1002/ejoc.201600767

Concurrent Radical Addition and [3+2] Cycloaddition between Nitrones and Maleimide‐Based Acyclic Enediynes

Jing Li, Mengsi Zhang, Shuai Huang, Yun Ding and Aiguo Hu

Asian J Org Chem, 2018, 7, 2076
DOI: 10.1002/ajoc.201800408

Light-Cross-linked Enediyne Small-Molecule Micelle-Based Drug-Delivery System

Baojun Li, Yuequn Wu, Yue Wang, Mengsi Zhang, Huimin Chen, Jing Li, Runhui Liu, Yun Ding and Aiguo Hu

ACS Appl. Mater. Interfaces, 2019, 11, 8896
DOI: 10.1021/acsami.8b22516

Substituted Maleimides: Self‐Reportable Linkers and Tags in Bioconjugation, Materials Science, and Nanotechnology

Jake E. Barker, Joshua D. Tibbetts, Calum T. J. Ferguson, Yujie Xie and Rachel K. O'Reilly

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202410550

Synthesis of fluorescent hyperbranched enediynes and Bergman cyclization polymerization for generating spatially locked persistent radicals

Qiaoping Li, Shudan Chen, Peng Zhao and Aiguo Hu

Polymer, 2017, 119, 245
DOI: 10.1016/j.polymer.2017.05.029

A Novel Approach toward Polyfulvene: Cationic Polymerization of Enediynes

Shudan Chen, Qiaoping Li, Shiyuan Sun, Yun Ding and Aiguo Hu

Macromolecules, 2017, 50, 534
DOI: 10.1021/acs.macromol.6b02321

Nucleophilic Addition to Diradicals Derived From Cycloaromatization of Maleimide‐Based Enediynes

Mengsi Zhang, Hailong Ma, Baojun Li, Ke Sun, Haotian Lu, Wenbo Wang, Xiaoyu Cheng, Xiaoxuan Li, Yun Ding and Aiguo Hu

Asian J Org Chem, 2021, 10, 1454
DOI: 10.1002/ajoc.202100136

Cycloaromatization of Enediyne Compounds under the Action of Bromide Ions: Diradical/Zwitterionic/Anionic Pathways

Shudan Chen, Shuai Huang, Chonggang Wang, Yun Ding and Aiguo Hu

Asian J Org Chem, 2017, 6, 1099
DOI: 10.1002/ajoc.201700136

An acyclic enediyne anticancer compound attributed to a Bergman cyclization at physiological temperature

Baojun Li, Bing Duan, Jing Li, Mengsi Zhang, Yuan Yuan, Yun Ding and Aiguo Hu

Tetrahedron, 2018, 74, 6419
DOI: 10.1016/j.tet.2018.08.042

Enediyne-Comprising Amino Aldehydes in the Passerini Reaction

Mladena Glavaš, Matija Gredičak and Ivanka Jerić

ACS Comb. Sci., 2018, 20, 151
DOI: 10.1021/acscombsci.7b00167

Triggering the Antitumor Activity of Acyclic Enediyne through Maleimide-Assisted Rearrangement and Cycloaromatization

Mengsi Zhang, Baojun Li, Huimin Chen, Haotian Lu, Hailong Ma, Xiaoyu Cheng, Wenbo Wang, Yue Wang, Yun Ding and Aiguo Hu

J. Org. Chem., 2020, 85, 9808
DOI: 10.1021/acs.joc.0c01124

Caged xanthone derivatives to promote mitochondria-mediated apoptosis in breast cancer cells

Youyi Wang, Huimin Zheng, Xue Jiang, Huaimo Wu, Yi Ren, Zhichao Xi, Changwu Zheng and Hongxi Xu

Bioorganic & Medicinal Chemistry, 2024, 103, 117655
DOI: 10.1016/j.bmc.2024.117655

Intermolecular proton transfer assisted 1,4-Michael addition for enediyne conversion to enyne-allene

Yun Ding, Hailong Ma, Baojun Li, Jianfeng Ma, Zhehao Hu, Yipeng Zhang, Xuhaoxi Wen and Aiguo Hu

Chemical Physics Letters, 2021, 780, 138899
DOI: 10.1016/j.cplett.2021.138899

Flexibility versus Rigidity: How Conformational Constraint, Steric Hindrance and Solvent Impact Binding between π‐Electron Poor Tweezer‐Type Hosts and π‐Electron Rich Guests

Lydia A. Panther, Monika Stankunaite, Manvendra Sharma, John Spencer and Barnaby W. Greenland

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202201321

Experimental and Computational Study on the Intramolecular Hydrogen Atom Transfer Reactions of Maleimide-Based Enediynes After Cycloaromatization

Mengsi Zhang, Haotian Lu, Baojun Li, Hailong Ma, Wenbo Wang, Xiaoyu Cheng, Yun Ding and Aiguo Hu

J. Org. Chem., 2021, 86, 1549
DOI: 10.1021/acs.joc.0c02401

Reactivity of para-benzynes in solution and in the gas phase

Chunfen Jin, Erlu Feng, Xin Ma, Weijuan Tang, Huaming Sheng, Ashley Wittrig, Jinshan Gao and Hilkka I. Kenttämaa

Tetrahedron Letters, 2021, 74, 153161
DOI: 10.1016/j.tetlet.2021.153161

Preparation of Maleimide‐Based Enediynes with Propargyl Ester for Efficient Tumor Cell Suppression

Huimin Chen, Baojun Li, Mengsi Zhang, Haotian Lu, Yue Wang, Wenbo Wang, Yun Ding and Aiguo Hu

ChemistrySelect, 2020, 5, 7069
DOI: 10.1002/slct.202001282

Experimental and Computational Study on the Reaction Pathways of Diradical Intermediates Formed from Myers‐Saito Cyclization of Maleimide‐Based Enediynes

Haotian Lu, Mengsi Zhang, Baojun Li, Hailong Ma, Wenbo Wang, Yun Ding, Xinxin Li and Aiguo Hu

Asian J Org Chem, 2020, 9, 2170
DOI: 10.1002/ajoc.202000432

Relative Reactivity of Benzothiophene-Fused Enediynes in the Bergman Cyclization

Anna G. Lyapunova, Natalia A. Danilkina, Andrey M. Rumyantsev, A. F. Khlebnikov, Mikhail V. Chislov, Galina L. Starova, Elena V. Sambuk, Anastasia I. Govdi, Stefan Bräse and Irina A. Balova

J. Org. Chem., 2018, 83, 2788
DOI: 10.1021/acs.joc.7b03258

Coordination‐Accelerated Radical Formation from Acyclic Enediynes for Tumor Cell Suppression

Baojun Li, Mengsi Zhang, Haotian Lu, Hailong Ma, Yue Wang, Huimin Chen, Yun Ding and Aiguo Hu

Chemistry An Asian Journal, 2019, 14, 4352
DOI: 10.1002/asia.201901182

Preparation and antitumor applications of asymmetric propargyl amide maleimide based enediyne antibiotics

Yue Wang, Baojun Li, Mengsi Zhang, Haotian Lu, Huimin Chen, Wenbo Wang, Yun Ding and Aiguo Hu

Tetrahedron, 2020, 76, 131242
DOI: 10.1016/j.tet.2020.131242

Self‐Delivery Nanoparticles of Amphiphilic Acyclic Enediynes for Efficient Tumor Cell Suppression

Jing Li, Yuequn Wu, Lili Sun, Shuai Huang, Baojun Li, Yun Ding and Aiguo Hu

Chin. J. Chem., 2019, 37, 479
DOI: 10.1002/cjoc.201900034

Synthesis of Enynic and Allenic Orthoesters via Defluoromethoxylation of 2-Trifluoromethyl-1,3-enynes

Dong-Ting Dai, Jian-Lin Xu, Zhi-Yuan Chen, Zi-Lu Wang and Yun-He Xu

Org. Lett., 2021, 23, 1898
DOI: 10.1021/acs.orglett.1c00311