Evaluating the effect of two-dimensional molecular layout on DNA origami-based transporters

Kodai Fukumoto, Yuya Miyazono, Takuya Ueda, Yoshie Harada and Hisashi Tadakuma

Nanoscale Adv., 2023, 5, 2590
DOI: 10.1039/D3NA00088E

DNA origami-based protein networks: from basic construction to emerging applications

Gezhi Kong, Mengyi Xiong, Lu Liu, Ling Hu, Hong-Min Meng, Guoliang Ke, Xiao-Bing Zhang and Weihong Tan

Chem. Soc. Rev., 2021, 50, 1846
DOI: 10.1039/D0CS00255K

Highly efficient zinc finger peptide detection with ZIF-8-modified micropipets

Jinzheng Zhang, Yuqi Yuan, Tingyan Ye, Shiyi Tan, Nannan Liu, Jinjie Qian, Shaoming Huang and Fan Xia

Chem. Commun., 2020, 56, 10855
DOI: 10.1039/D0CC04683C

Rational design of a DNA sequence-specific modular protein tag by tuning the alkylation kinetics

Thang Minh Nguyen, Eiji Nakata, Zhengxiao Zhang, Masayuki Saimura, Huyen Dinh and Takashi Morii

Chem. Sci., 2019, 10, 9315
DOI: 10.1039/C9SC02990G

Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy

Bas J. H. M. Rosier, Glenn A. O. Cremers, Wouter Engelen, Maarten Merkx, Luc Brunsveld and Tom F. A. de Greef

Chem. Commun., 2017, 53, 7393
DOI: 10.1039/C7CC04178K

Enhanced enzymatic activity exerted by a packed assembly of a single type of enzyme

Huyen Dinh, Eiji Nakata, Kaori Mutsuda-Zapater, Masayuki Saimura, Masahiro Kinoshita and Takashi Morii

Chem. Sci., 2020, 11, 9088
DOI: 10.1039/D0SC03498C

Conditional dependence of enzyme cascade reaction efficiency on the inter-enzyme distance

Peng Lin, Huyen Dinh, Eiji Nakata and Takashi Morii

Chem. Commun., 2021, 57, 11197
DOI: 10.1039/D1CC04162B

Constructing protein-functionalized DNA origami nanodevices for biological applications

Chuangyuan Zhao, Xinran Jiang, Miao Wang, Songbai Gui, Xin Yan, Yuanchen Dong and Dongsheng Liu

Nanoscale, 2025, 17, 142
DOI: 10.1039/D4NR03599B

Protein adaptors assemble functional proteins on DNA scaffolds

Tien Anh Ngo, Huyen Dinh, Thang Minh Nguyen, Fong Fong Liew, Eiji Nakata and Takashi Morii

Chem. Commun., 2019, 55, 12428
DOI: 10.1039/C9CC04661E

Evaluation of the role of the DNA surface for enhancing the activity of scaffolded enzymes

Peng Lin, Huyen Dinh, Yuki Morita, Zhengxiao Zhang, Eiji Nakata, Masahiro Kinoshita and Takashi Morii

Chem. Commun., 2021, 57, 3925
DOI: 10.1039/D1CC00276G

Nucleic Acid‐based Enzyme Cascades—Current Trends and Future Perspectives

Sandra Kröll and Christof M. Niemeyer

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202314452

Nucleic‐Acid‐Templated Enzyme Cascades

Arivazhagan Rajendran, Eiji Nakata, Shun Nakano and Takashi Morii

ChemBioChem, 2017, 18, 696
DOI: 10.1002/cbic.201600703

Dynamic Assembly of Cascade Enzymes by the Shape Transformation of a DNA Scaffold

Peng Lin, Huyen Dinh, Yuki Morita, Eiji Nakata and Takashi Morii

Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202215023

A Practical Approach for Polarity and Quantity Controlled Assembly of Membrane Proteins into Nanoliposomes

Shiwei Zhang, Peng Lin, Futa Komatsubara, Eiji Nakata and Takashi Morii

ChemBioChem, 2025, 26
DOI: 10.1002/cbic.202401041

DNA nanotechnology-based biomolecular assembly and imaging

Jiayi Li, Yuanfang Chen and Yuhe R. Yang

Chin. Sci. Bull., 2023, 68, 4383
DOI: 10.1360/TB-2023-0511

Design of Modular Protein Tags for Orthogonal Covalent Bond Formation at Specific DNA Sequences

Thang Minh Nguyen, Eiji Nakata, Masayuki Saimura, Huyen Dinh and Takashi Morii

J. Am. Chem. Soc., 2017, 139, 8487
DOI: 10.1021/jacs.7b01640

DNA-Programmed Biomolecular Spatial Pattern Recognition

Yue Wang, Lei Ren, Hongzhen Peng, Linjie Guo and Lihua Wang

Chemosensors, 2023, 11, 362
DOI: 10.3390/chemosensors11070362

A Rationally Designed Connector for Assembly of Protein‐Functionalized DNA Nanostructures

Katja J. Koßmann, Cornelia Ziegler, Alessandro Angelin, Rebecca Meyer, Marc Skoupi, Kersten S. Rabe and Christof M. Niemeyer

ChemBioChem, 2016, 17, 1102
DOI: 10.1002/cbic.201600039

Nucleic Acid‐based Enzyme Cascades—Current Trends and Future Perspectives

Sandra Kröll and Christof M. Niemeyer

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202314452

Docking of Antibodies into the Cavities of DNA Origami Structures

Xiangyuan Ouyang, Mattia De Stefano, Abhichart Krissanaprasit, Anne Louise Bank Kodal, Christian Bech Rosen, Tianqiang Liu, Sarah Helmig, Chunhai Fan and Kurt V. Gothelf

Angew Chem Int Ed, 2017, 56, 14423
DOI: 10.1002/anie.201706765

DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels

Tatsuki Kurokawa, Shigeki Kiyonaka, Eiji Nakata, Masayuki Endo, Shohei Koyama, Emiko Mori, Nam Ha Tran, Huyen Dinh, Yuki Suzuki, Kumi Hidaka, Masaaki Kawata, Chikara Sato, Hiroshi Sugiyama, Takashi Morii and Yasuo Mori

Angew Chem Int Ed, 2018, 57, 2586
DOI: 10.1002/anie.201709982

Reaction of ribulose biphosphate carboxylase/oxygenase assembled on a DNA scaffold

Huyen Dinh, Eiji Nakata, Peng Lin, Masayuki Saimura, Hiroki Ashida and Takashi Morii

Bioorganic & Medicinal Chemistry, 2019, 27, 115120
DOI: 10.1016/j.bmc.2019.115120

Spatially Organized Enzymes Drive Cofactor-Coupled Cascade Reactions

Tien Anh Ngo, Eiji Nakata, Masayuki Saimura and Takashi Morii

J. Am. Chem. Soc., 2016, 138, 3012
DOI: 10.1021/jacs.5b10198

DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels

Tatsuki Kurokawa, Shigeki Kiyonaka, Eiji Nakata, Masayuki Endo, Shohei Koyama, Emiko Mori, Nam Ha Tran, Huyen Dinh, Yuki Suzuki, Kumi Hidaka, Masaaki Kawata, Chikara Sato, Hiroshi Sugiyama, Takashi Morii and Yasuo Mori

Angewandte Chemie, 2018, 130, 2616
DOI: 10.1002/ange.201709982

Tuning the Reactivity of a Substrate for SNAP‐Tag Expands Its Application for Recognition‐Driven DNA‐Protein Conjugation

Zhengxiao Zhang, Eiji Nakata, Huyen Dinh, Masayuki Saimura, Arivazhagan Rajendran, Kazunari Matsuda and Takashi Morii

Chemistry A European J, 2021, 27, 18118
DOI: 10.1002/chem.202103304

Functionalizing DNA origami to investigate and interact with biological systems

Grant A. Knappe, Eike-Christian Wamhoff and Mark Bathe

Nat Rev Mater, 2022, 8, 123
DOI: 10.1038/s41578-022-00517-x

Docking of Antibodies into the Cavities of DNA Origami Structures

Xiangyuan Ouyang, Mattia De Stefano, Abhichart Krissanaprasit, Anne Louise Bank Kodal, Christian Bech Rosen, Tianqiang Liu, Sarah Helmig, Chunhai Fan and Kurt V. Gothelf

Angewandte Chemie, 2017, 129, 14615
DOI: 10.1002/ange.201706765

RNA-Peptide Conjugation through an Efficient Covalent Bond Formation

Shun Nakano, Taiki Seko, Zhengxiao Zhang and Takashi Morii

Applied Sciences, 2020, 10, 8920
DOI: 10.3390/app10248920

Dynamic Shape Transformation of a DNA Scaffold Applied for an Enzyme Nanocarrier

Peng Lin, Huyen Dinh, Eiji Nakata and Takashi Morii

Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.697857

Enzyme Reactions Are Accelerated or Decelerated When the Enzymes Are Located Near the DNA Nanostructure

Peng Lin, Tomohiko Hayashi, Huyen Dinh, Eiji Nakata, Masahiro Kinoshita and Takashi Morii

ACS Appl. Mater. Interfaces, 2025, 17, 15775
DOI: 10.1021/acsami.4c18192

Mechanistic Aspects for the Modulation of Enzyme Reactions on the DNA Scaffold

Peng Lin, Hui Yang, Eiji Nakata and Takashi Morii