Diversity-Oriented Synthesis of Chromone Inden-1-one Fused Cyclopentadienylides and C-Acylated Chromone Adducts via Allylic Phosphorus Ylides

Abstract

An organophosphine-controlled diversity-oriented synthesis of chromone Inden-1-one fused cyclopentadienylides and C-acylated 2-((chromone-3-yl)methylene)-indandiones is reported. Key attributes of the methodology are the in-situ generation of an allylic P-ylide and subsequent regio- and chemoselective intramolecular cyclization reactions that preferentially result in the aforementioned chromone adducts in a DOS manner.