Novel bis(indolyl)methanes has been synthesized in satisfactory isolated yields using carbohydrate-derived 5-substituted-2-furaldehydes as renewable reactants and gluconic acid aqueous solution as a sustainable catalyst.
This study presents the sustainable synthesis of bis(indolyl)methanes catalysed by Zn(II) catalysts through ADC of indole and alcohol. A wide substrate scope, including bioactive molecules, are explored with a mechanistic understanding.
This review article highlights the recent advances of transition-metal-catalyzed interrupted borrowing hydrogen (IBH) catalysis and its applications in the sustainable and affordable chemical synthesis using alcohols as C1 feedstocks.
Bis(3-indolyl)methanes (BIMs) are known for their important bioactivities, which include anti-cancer, anti-inflammatory, antibacterial, and antioxidant properties.
A novel catalytic system of Ni(II) complex tagged on graphene oxide has been developed and utilized in the synthesis of bis(indolyl)methanes under mild reaction conditions.