The parahydrogen-induced polarisation (PHIP) NMR signal enhancement technique is used to study H2 addition to Vaska’s complex (trans-[IrCl(CO)(PPh3)2]) and a mixture of Vaska’s complex derivatives with benchtop (1 T) NMR detection.
On-line reaction monitoring of hydrogenation reactions of oxygen-sensitive organometallic complexes is done via a 31P benchtop NMR spectrometer using the Multi-Resonance Sensitive Homogeneous And Resolved PEaks in Real time (MR-SHARPER) sequence.
A comparison of ultra-resolved pure shift NMR techniques, mitigating the resolution problem of compact NMR instruments, showed that the J-resolved double echo is the most performant technique, enabling the profiling of biological complex mixtures.
Benchtop NMR analyses of bio-oils are made safer and more sustainable by replacing DMF with bio-derived solvents.
The integration of benchtop NMR with a probe-based autosampler enables automated sampling and real-time measurement of reaction samples, as well as verification and calibration of spectroscopic methods.