DNA-programmable nano-impact electrochemistry: from principles to bioanalytical applications

Qiong Wu, Di Sun, Chaoxing Chen, Jinhua Shang, Feifei Hu and Fuan Wang

Chem. Commun., 2025, 61, 18490
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Self-replicating DNA circuit for high-fidelity in situ imaging of T4 polynucleotide kinase activity in living cells

Ying Deng, Sini Li, Zhaolin Wang, Xiaoqing Liu, Ruomeng Li and Fuan Wang

Biosensors and Bioelectronics, 2025, 288, 117841
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Endogenous Enzyme Stimulation of Localized Catalytic DNA Assembly for High-Contrast microRNA Imaging and Reliable Evaluation of Drug Resistance

Yuqian Jiang, Chenxia Xie, Yingying Chen, Hui Wang, Jinhua Shang, Xiaoqing Liu and Fuan Wang

Anal. Chem., 2025, 97, 19719
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Allosteric Regulation of Spherical Nucleic Acid for Facile Discrimination of Patients with Different Heart Failure Severity

Xi Wang, Jiangling Wu, Pu Zhang, Fuan Wang, Zhongwei Jiang, Lianzhe Hu, Xue Gong and Yi Wang

Anal. Chem., 2025, 97, 26458
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Instrument-Free, Low-Cost and Dual-System Detection for Norovirus Based on Self-Assembling DNA Circuitry

Ai Chen, Shuo Ma, Jiwei Wang, Yuming Yao, Gulinaizhaer Abudushalamu, Meiling Zhou, Dawen Chen, Yue Zheng, Chenyan Yuan, Chuankun Yang, Xun Gao, Chen Zhang and Guoqiu Wu

ACS Omega, 2026, 11, 21287
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Amplified Intracellular Imaging of Polynucleotide Kinase via a Self-Stacking Autocatalytic DNA Circuit

Zhaolin Wang, Sini Li, Ying Deng, Ruomeng Li, Xiaoqing Liu and Fuan Wang

Anal. Chem., 2025, 97, 22595
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Photothermal sensing via DNAzyme catalysis for MicroRNA detection at the point-of-care

Chenbiao Li, Xue Lin, Fengye Mo, Zhiqiao Zou, Jiayun Hu, Dedong Cao, Yushan Tian, Jinghong Li and Xiaoqing Liu

Biosensors and Bioelectronics, 2025, 288, 117832
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An Integrated Sequential‐Activated DNA Circuit for Reliable Imaging of Intracellular miRNA and Remote Control of Cellular Function

Mengdi Yu, Jinhua Shang, Chongyu Xie, Yuqian Jiang, Yuan Wang, Xiaoqing Liu and Fuan Wang

Adv Funct Materials, 2025, 35
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Peptide-Programmable DNAzyme Converter for Artificial Autocatalytic Gene Regulation

Qingqing Zhang, Jian Hao, Yuqiu He, Benrui Weng, Shanshan Yu, Chunsen Li and Fuan Wang

J. Am. Chem. Soc., 2025, 147, 34944
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A Label‐Free Phosphate‐Transfer DNAzyme for the Cost‐Effective Point‐of‐Care Detection of Influenza Virus

Yuan Wang, Jinhua Shang, Mengdi Yu, Guangqin Liu, Xiaoqing Liu and Fuan Wang

Angew Chem Int Ed, 2026, 65
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A Versatile DNAzyme‐Amplified Protease‐Sensing Platform for Accurate Diagnosis of SARS‐CoV‐2 and Reliable Classification of Colorectal Cancer

Benrui Weng, Yifei Wang, Qingqing Zhang, Yuqian Jiang, Jinhua Shang, Xiaoqing Liu and Fuan Wang

Angew Chem Int Ed, 2025, 64
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Antibiotic-induced autocatalytic DNA circuit for enrofloxacin detection based on triple signal amplification strategy

Junhua Chen, Gu Shi and Chong Yan

Biosensors and Bioelectronics, 2026, 299, 118448
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Concentration-Tunable Catalytic Strand-Driven Fast Self-Reinforcing Circular DNA Nanoamplifier under Precise Activation of NIR Light Guidance for Sensitive Fluorescence Imaging

Jingwei Qiu, Zhuo Chen, Qing Tang, Lejing Yao, Hongwu Tang and Cheng-Yu Li

Anal. Chem., 2025, 97, 12356
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Epigenetic Control of Toehold-Mediated Strand Displacement for Programmable Molecular Circuit Regulation and Enhanced microRNA Detection

Yuxuan Zhu, Chongyu Xie, Hui Wang, Jinhua Shang, Xiaoqing Liu and Fuan Wang

ACS Nano, 2026, 20, 11971
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Integrating catalytic hairpin assembly with the signal amplification revolution of nanosensing strategies for food safety assurance

Zhaowen Cui, Chenjie Nie, Yuechun Li, Chenxin Ji, Guo Hao, Jing Sun, Yanwei Ji and Jianlong Wang

Food Research International, 2026, 237, 119318
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Application of catalytic hairpin assembly reaction in liquid biopsy

Zhilong Yao, Mei Wang, Jiezhen Pan, Xiujuan Huang, Jian Zhang and Shihua Luo

Talanta Open, 2025, 12, 100591
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Leveraging Demethylase Activation in DNA Circuits to Overcome Signal Leakage for Reliable MicroRNA Bioimaging

Yuchen Gao, Mengdi Yu, Jinhua Shang, Yuqian Jiang, Xiaoqing Liu and Fuan Wang

Small, 2025, 21
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Photo‐Autocatalysis: Insights From Light‐Driven Self‐Catalyzed Organic Transformations

James Shao‐Jiun Yang, Aira Shayne Paculba and Hsuan‐Hung Liao

Chemistry An Asian Journal, 2026, 21
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A Label‐Free Phosphate‐Transfer DNAzyme for the Cost‐Effective Point‐of‐Care Detection of Influenza Virus

Yuan Wang, Jinhua Shang, Mengdi Yu, Guangqin Liu, Xiaoqing Liu and Fuan Wang

Angewandte Chemie, 2026, 138
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On‐Demand Regulation of Catalytic DNA Circuits Using Phosphorylated Charge Reversal Peptides

Qingqing Zhang, Shanshan Yu, Shizhen He, Yuqiu He, Xiaoqing Liu and Fuan Wang

Angew Chem Int Ed, 2025, 64
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Sandwich-type complex-activated DNA circuit for highly sensitive and versatile detection of protein biomarkers for monitoring bone health

Wenming Pan, Zhan Zhang, Quanshan Jin, Tao Zhang, Suwen Wang, Wenju Zhang and Ya Cao

Analytica Chimica Acta, 2026, 1407, 345526
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Point‐of‐Care Diagnosis of Respiratory Viruses at Single‐Nucleotide Resolution with an Autocatalytic Rolling Circle Amplification System

Jinhua Shang, Yuan Wang, Ya Pang, Mengdi Yu, Yifei Wang, Songmei Liu, Xianzheng Zhang and Fuan Wang

Angewandte Chemie, 2025, 137
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Abasic Nanocavity-Powered Label-Free Fluorescent Biosensors for Cancer Cell Detection and Inhibitor Evaluation

Shu-Sheng Yu, Jian Hao, Qingqing Zhang, Yanping Zhang, Xiaoqing Liu, Chunsen Li and Fuan Wang

Anal. Chem., 2026, 98, 3002
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Cascade DNA Logic Strategy for Profiling the MiRNA-210-Targeted Signaling Pathway in the Warburg Effect of Triple-Negative Breast Cancer

Jingyuan Yu, Xiaojun Zhang, Hao Sun and Yan Du

Anal. Chem., 2025, 97, 14103
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A Versatile DNAzyme‐Amplified Protease‐Sensing Platform for Accurate Diagnosis of SARS‐CoV‐2 and Reliable Classification of Colorectal Cancer

Benrui Weng, Yifei Wang, Qingqing Zhang, Yuqian Jiang, Jinhua Shang, Xiaoqing Liu and Fuan Wang

Angewandte Chemie, 2025, 137
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An Intelligent Allosteric DNAzyme Platform for On-Site Uracil-DNA Glycosylase Imaging and On-Demand Gene Regulation

Yuqian Jiang, Yingying Chen, Xue Gong, Benrui Weng, Yuqiu He and Fuan Wang

JACS Au, 2025, 5, 4288
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On‐Demand Regulation of Catalytic DNA Circuits Using Phosphorylated Charge Reversal Peptides

Qingqing Zhang, Shanshan Yu, Shizhen He, Yuqiu He, Xiaoqing Liu and Fuan Wang

Angewandte Chemie, 2025, 137
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Precise diagnostics of multidimensional disease biomarkers via programmable DNA logic nanodevice integrated with signal-amplified visual readout

Sihui Yang, Zhi-Hui Xiao, Miao Wang, Li-Li Wang and Yan-Hua Tang

Sensors and Actuators B: Chemical, 2026, 458, 139836
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The Trend of Nonenzymatic Nucleic Acid Amplification: Strategies and Diagnostic Application

Junyou Li, Ting Li, Zheng Zou and Hung-Wing Li

Precision Chemistry, 2025, 3, 187
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Programmable Cancer Subtype Evaluator via Multiply-Guaranteed Catalytic DNA Computing Circuit

Ruomeng Li, Xue Gong, Jinhua Shang, Yuqian Jiang, Weizhen Chen, Gaosong Wu, Xiaoqing Liu, Fuan Wang and Jinghong Li

J. Am. Chem. Soc., 2025, 147, 40686
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Endogenous and Exogenous Dual-Gated DNA Nanoactuator in Autonomous Two-Step Catalytic Amplification for Robust Biomolecular Sensing In Vitro and In Vivo

Qing Tang, Zhuo Chen, Lejing Yao, Jingwei Qiu, Hongwu Tang and Cheng-Yu Li

ACS Appl. Mater. Interfaces, 2025, 17, 46310
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Point‐of‐Care Diagnosis of Respiratory Viruses at Single‐Nucleotide Resolution with an Autocatalytic Rolling Circle Amplification System

Jinhua Shang, Yuan Wang, Ya Pang, Mengdi Yu, Yifei Wang, Songmei Liu, Xianzheng Zhang and Fuan Wang

Angew Chem Int Ed, 2025, 64
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A low-background autocatalytic DNA circuit for sensitive and multiplexed enzyme-free isothermal miRNA amplification

Junlan Liu, Linyi Deng and Yuan Gao

Chemical Engineering Journal, 2025, 519, 165098
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In situ tracking of glycoRNAs on single-cell surface to reveal RNA heterogeneity and transport mechanism

Meilin Gong, Xiaoqi Tang, Zuowei Xie, Ben Niu, Ruijia Deng, Wenjuan Fu, Yingjie Yang, Yu Tang, Jie Luo, Jing Sheng, Ying Zhang, Ming Chen and Kai Chang

Nucleic Acids Research, 2026, 54
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