A novel aptasensor based endogenous enzyme-powered DNA walker for ATP imaging in specific living cells

Chunrong Li, Tong Li, Mingqi Guo, Tiehong Meng, Jing Peng, Simin Liu, Qianyu Wang, Baoping Xie, Zong Dai and Jun Chen

Chem. Commun., 2024, 60, 11782
DOI: 10.1039/D4CC04681A

RNA-cleaving DNAzymes for accurate biosensing and gene therapy

Xin Gao, Yixin Liu, Wendi Huo, Yuwei Song, Yu Chen, Jinchao Zhang, Xinjian Yang, Yi Jin and Xing-jie Liang

Nanoscale, 2023, 15, 11346
DOI: 10.1039/D3NR01482G

Construction of an endogenously activated nanoamplifier for high-sensitivity detection and multimodal bioimaging of Alzheimer's disease

Jingwen Chen, Shengrong Yu, Gege Xie, Rong Feng, Wei Cui, Ren Cai, Keqi Tang, Nengchong Zhang and Yong-Xiang Wu

Analyst, 2025, 150, 4823
DOI: 10.1039/D5AN00544B

Light and endogenous enzyme triggered plasmonic antennas for accurate subcellular molecular imaging with enhanced spatial resolution

Shuwei Chen, Yue Yin, Xiaozhe Pang, Congkai Wang, Lei Wang, Junqi Wang, Jiangfei Jia, Xinxue Liu, Shenghao Xu and Xiliang Luo

Chem. Sci., 2024, 15, 566
DOI: 10.1039/D3SC05728C

Principles of nucleic acid toehold mediated strand displacement (TMSD) reaction model and its applications in cell environment

Linlin Tang, Tao Luo, Sisi Fan, Yan Liu and Jie Song

Biomater. Sci., 2023, 11, 5060
DOI: 10.1039/D3BM00476G

Light-Up Aptameric Sensor of Serotonin for Point-of-Care Use

Gege Song, Zhiqiao Zou, Ailing Feng, Chenbiao Li, Meijuan Liang, Fuan Wang and Xiaoqing Liu

Anal. Chem., 2023, 95, 9076
DOI: 10.1021/acs.analchem.3c01456

DNA Hydrogels for Cancer Diagnosis and Therapy

Li Peng, Shuang Gu, Min Hou and Xiaohua Hou

ChemBioChem, 2024, 25
DOI: 10.1002/cbic.202400494

Dual biomarkers-activatable hollow MnO2-Based theranostic nanoplatform for efficient breast cancer-specific multisite fluorescence imaging and synergistic therapy

Juan Ning, Guizhen Hu, Tian Wu, Yijun Zhao, Yamin Nie and Yanmei Zhou

Analytica Chimica Acta, 2024, 1303, 342521
DOI: 10.1016/j.aca.2024.342521

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

Hangnan Hong, Zhenyang Guo, Junbo Ge and Hua Li

MedComm, 2025, 6
DOI: 10.1002/mco2.70379

Nucleic Acid‐Based Molecular Machines for Biological Applications

Yirong Guo, Xiaolei Zuo and Fangfei Yin

Advanced NanoBiomed Research, 2025, 5
DOI: 10.1002/anbr.202400206

Leveraging Demethylase Activation in DNA Circuits to Overcome Signal Leakage for Reliable MicroRNA Bioimaging

Yuchen Gao, Mengdi Yu, Jinhua Shang, Yuqian Jiang, Xiaoqing Liu and Fuan Wang

Small, 2025, 21
DOI: 10.1002/smll.202412843

Polyhedral Au Nanoparticle/MoOx Heterojunction-Enhanced Ultrasensitive Dual-Mode Biosensor for miRNA Detection Combined with a Nonenzymatic Cascade DNA Amplification Circuit

Lin Zhao, Tiantian Li, Xinlin Xu, Yang Xu, Dongxiang Li, Weiling Song, Tianrong Zhan, Peng He, Hong Zhou, Jing-Juan Xu and Hong-Yuan Chen

Anal. Chem., 2023, 95, 9271
DOI: 10.1021/acs.analchem.3c01062

Endogenous Glutathione-Activated Nucleic Acid Molecular Circuitry for Cell-Specific MicroRNA Imaging

Hui Wang, Yingying Chen, Yuqian Jiang, Yifei Wang, Ruomeng Li, Jinhua Shang and Fuan Wang

Anal. Chem., 2024, 96, 12854
DOI: 10.1021/acs.analchem.4c02570

A label-free fluorescence aptamer sensor for point-of-care serotonin detection

Shuyuan Zhang, Gege Song, Zhan Yang, Kai Kang and Xiaoqing Liu

Talanta, 2024, 277, 126363
DOI: 10.1016/j.talanta.2024.126363

Electrochemical Self-Sacrificial Label Conversion Coupled with DNA Framework Nanomachine Mediated Serotonin Sensing with Highly Minimized Background Noise

Baoting Dou, Yan Chen, Qiumei Feng, Huanyu Cheng and Po Wang

Anal. Chem., 2025, 97, 157
DOI: 10.1021/acs.analchem.4c03452

An Intelligent Redox‐Responsive DNA Circuit for Robust On‐Site Profiling of Glutathione‐MicroRNA Signaling Pathway

Yifei Wang, Jinhua Shang, Yuqiu He, Qingqing Zhang, Xiaoqing Liu and Fuan Wang

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202315993

Ratiometric detection of lithium ions in serum and living cells using DNAzyme-assisted hybridization chain reaction

Jiaqi Wang, Zhiyuan Feng, Jiayin Zhan, Yang Shi and Jingjing Zhang

Sensors and Actuators B: Chemical, 2024, 410, 135656
DOI: 10.1016/j.snb.2024.135656

A Methyl‐Engineered DNAzyme for Endogenous Alkyltransferase Monitoring and Self‐Sufficient Gene Regulation

Yuqiu He, Qing Wang, Qingqing Zhang, Yifei Wang, Yuqian Jiang, Qiu Zhao, Xiaoqing Liu and Fuan Wang

Small Methods, 2025, 9
DOI: 10.1002/smtd.202401160

Amplified Intracellular Imaging of Polynucleotide Kinase via a Self-Stacking Autocatalytic DNA Circuit

Zhaolin Wang, Sini Li, Ying Deng, Ruomeng Li, Xiaoqing Liu and Fuan Wang

Anal. Chem., 2025, 97, 22595
DOI: 10.1021/acs.analchem.5c03752

Engineering of a DNAzyme-based aptasensor for highly efficient ATP detection and oyster freshness evaluation

Xiaojiao Dai, Ziling Huang, Chuanyi Liu, Zhigang Li, Qingmin Chen, Yi Xu, Xiaomei Chen, Quansheng Chen and Jie Wei

Journal of Food Composition and Analysis, 2025, 139, 107176
DOI: 10.1016/j.jfca.2024.107176

A dual-locked and self-feedback CHA-DNAzyme nanomachine for tumor-specific molecular imaging in living cells

Baizong Fang, Wei Guo, Zhenyu Liu, Huakui Huang and Xiaohong Zhong

Analytica Chimica Acta, 2026, 1396, 345257
DOI: 10.1016/j.aca.2026.345257

Sequentially amplified integration of catalytic DNA circuits for high-performance intracellular imaging of miRNA and interpretation of mRNA-miRNA signalling pathway

Mengdi Yu, Yushi Wang, Jinhua Shang, Qingqing Zhang, Yuqian Jiang, Xiaoqing Liu and Fuan Wang

Nano Today, 2025, 61, 102563
DOI: 10.1016/j.nantod.2024.102563

Integration of Isothermal Enzyme‐Free Nucleic Acid Circuits for High‐Performance Biosensing Applications

Siyuan Wang, Jinhua Shang, Bingyue Zhao, Huimin Wang, Changying Yang, Xiaoqing Liu and Fuan Wang

ChemPlusChem, 2023, 88
DOI: 10.1002/cplu.202300432

A Triple-Input AND-Logic System Employing an APE1-Propelled Bipedal DNA Walker for Highly Sensitive Detection of Dual miRNAs

Haoping Zhang, Min Pan, Xinyi Wang, Jingyu Tao, Zhaolong Tang, Hong Wang and Yingwei Zhang

ACS Sens., 2025, 10, 8801
DOI: 10.1021/acssensors.5c02731

Enzyme Translocation‐Mediated Signal Amplification for Spatially Selective Aptasensing of ATP in Inflammatory Cells

Chuangui Sheng, Jian Zhao, Fangzhi Yu and Lele Li

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202217551

Light-Driven Upconverting Nanoparticles-Based Nanodevice for Accurate Subcellular Dual Molecular Imaging and Combinational Tumor Therapy

Ruoyan Li, Huanhuan He, Jing Feng, Luna Guo, Peng He, Weiling Song, Hong Zhou and Xuemei Li

Anal. Chem., 2026, 98, 1514
DOI: 10.1021/acs.analchem.5c05888

Enzyme Translocation‐Mediated Signal Amplification for Spatially Selective Aptasensing of ATP in Inflammatory Cells

Chuangui Sheng, Jian Zhao, Fangzhi Yu and Lele Li

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202217551

Hyperbranched Chain Hybridization for Artificial Aggregates: Prolonging Intracellular Retention for Image‐Guided Cellular Fate Modulation

Xiao‐Qiong Li, Yi‐Lei Jia, Zhong‐Xia Wang, Yu‐Wen Zhang, Hong‐Yuan Chen and Jing‐Juan Xu

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202401711

On‐Site Multiply Stimulated Self‐Confinement of an Integrated DNA Cascade Circuit for Highly Reliable Intracellular Imaging of miRNA and In Situ Interrogation of the Relevant Regulatory Pathway

Yuqian Jiang, Yingying Chen, Jinhua Shang, Mengdi Yu, Benrui Weng, Jing Liu, Xiaoqing Liu and Fuan Wang

Small, 2024, 20
DOI: 10.1002/smll.202406545