A promising computational study of ovarian cancer treatment of the isolated compound 5,7-dihydroxy-3(R)-methylphthalide

Agus Dwi Ananto, Tendy Oktriawan, Kasta Gurning, Muhammad Idham Darussalam Mardjan, Tri Joko Raharjo, Yoshihito Shiono and Winarto Haryadi

J Herbmed Pharmacol, 2026, 15, 122
DOI: 10.34172/jhp.2026.53027

Statistically developed stable Camptothecin-loaded Soluplus/TPGS mixed micelles for improved ovarian cancer treatment

Shruti Kargane, Rutuja Chougale, Nitin Mali, Kiran Patil, Shalaka Patki and John Disouza

Journal of Dispersion Science and Technology, 2025, 46, 908
DOI: 10.1080/01932691.2024.2304634

Plant-derived natural compounds targeting drug resistance in ovarian cancer: Molecular mechanisms and therapeutic perspectives

Qiang Ao, Li Tang, Yin Bao, Meng Wang, Jun Zhu, Yang Chen, Hong Zhu and Jun Gao

Phytomedicine, 2026, 155, 158065
DOI: 10.1016/j.phymed.2026.158065

Sophorae tonkinensis radix et rhizoma: A comprehensive review of the ethnopharmacology, phytochemistry, pharmacology, pharmacokinetics, toxicology and detoxification strategy

Fen-Fen Zeng, Zi-Hao Chen, Fu-Hui Luo, Cheng-Jun Liu, Xia Yang, Feng-Xiang Zhang and Wei Shi

Journal of Ethnopharmacology, 2025, 337, 118784
DOI: 10.1016/j.jep.2024.118784

Cytotoxic Activity of Curcumin- and Resveratrol-Loaded Core–Shell Systems in Resistant and Sensitive Human Ovarian Cancer Cells

Joanna Weżgowiec, Zofia Łapińska, Łukasz Lamch, Anna Szewczyk, Jolanta Saczko, Julita Kulbacka, Mieszko Więckiewicz and Kazimiera A. Wilk

IJMS, 2024, 26, 41
DOI: 10.3390/ijms26010041

Cancer chemoprevention: signaling pathways and strategic approaches

Junling Ren, Guangli Yan, Le Yang, Ling Kong, Yu Guan, Hui Sun, Chang Liu, Lei Liu, Ying Han and Xijun Wang

Sig Transduct Target Ther, 2025, 10
DOI: 10.1038/s41392-025-02167-1

Prevention and treatment of osteoporosis with natural products: Regulatory mechanism based on cell ferroptosis

Yunshang Yang, Yifan Jiang, Daoyi Qian, Zhirong Wang and Long Xiao

J Orthop Surg Res, 2023, 18
DOI: 10.1186/s13018-023-04448-3

A nanoscale natural drug delivery system for targeted drug delivery against ovarian cancer: action mechanism, application enlightenment and future potential

Yi Li, Qian Shen, Lu Feng, Chuanlong Zhang, Xiaochen Jiang, Fudong Liu and Bo Pang

Front. Immunol., 2024, 15
DOI: 10.3389/fimmu.2024.1427573

Lycorine suppresses cell growth and attenuates stemness through PI3K/AKT pathway in ovarian cancer

Yaoyao Tan, Liping Xia, Guanlin Dai, Jie Ni, Shanshan Chen, Pei Chen, Shizhen Wang, Xun Zhou and Haiqin Wang

Biochemical Pharmacology, 2026, 249, 117876
DOI: 10.1016/j.bcp.2026.117876

Alkaloids isolated from Scutellaria Barbata D. Don trigger apoptosis and inhibit migration by modulating the p38-p53 pathway in ovarian cancer

Bingqing Gao, Xue Sui, HyokChol Choe, Yutong Yang, Yi Liu, Lunyue Xia, Peiyu Li, Yingting Chen, Yuexue Huo, Zhihao Zhao, Kaiyue Ding, Junnan Ma, Danping Zhao and Lin Zhang

J Ovarian Res, 2025, 18
DOI: 10.1186/s13048-025-01840-x

Efficacy of natural products on premature ovarian failure: a systematic review and meta-analysis of preclinical studies

Hangqi Hu, Jiacheng Zhang, Xiyan Xin, Yuxin Jin, Yutian Zhu, Haolin Zhang, Ruiwen Fan, Yang Ye and Dong Li

J Ovarian Res, 2024, 17
DOI: 10.1186/s13048-024-01369-5

miRNA‐Directed Anticancer Strategies: The Emerging Role of Natural Products in Ovarian Cancer

Rasha Abu‐Khudir, Shaza H. Aly, Nehal I. Rizk, Rabab S. Hamad, Heba M. Midan, Mai A. Abd‐Elmawla, Sherif S. Abdel Mageed, Ahmed I. Abulsoud, Mohamed Bakr Zaki, Osama A. Mohammed, Ahmed E. Elesawy, Walaa A. El‐Dakroury and Ahmed S. Doghish

The Journal of Gene Medicine, 2026, 28
DOI: 10.1002/jgm.70080

Targeting ferroptosis: a promising avenue for ovarian cancer treatment

Xiaolan Wu, Qizhi Liu, Zhili Jiang, Guiyun Wang, Lingyu Liao, Xiaojuan Ye, Min Xing, Han Sun, Qiying Liu and Huiping Liu

Front. Immunol., 2025, 16
DOI: 10.3389/fimmu.2025.1578723

Capturing and releasing cucurbitacins with α, β-unsaturated group from Cucumis melo based on reversibility of thia-Michael addition reaction

Tianyu Zhu, Liangyong Hu, Hang Hu, Yujie Li, Jiangmin Zhu, Guanzhao Wu and Defeng Xu

Bioorganic Chemistry, 2025, 159, 108404
DOI: 10.1016/j.bioorg.2025.108404

Antitumor and immunomodulatory activities of diphyllin and its derivatives

Yulin Ren, Judith C. Gallucci, Jianhua Yu, Joanna E. Burdette, James R. Fuchs and A. Douglas Kinghorn

Bioorganic & Medicinal Chemistry, 2025, 124, 118197
DOI: 10.1016/j.bmc.2025.118197

Anti-tumor effects of Guggulsterone in osteosarcoma: Role of SIRT3-mediated PINK1-Parkin mitophagy activation

Lingyuan Zeng, Shuwei Li, Kaidong Wu, Xiaoyu Bai and Long Zhang

Phytomedicine, 2026, 153, 157860
DOI: 10.1016/j.phymed.2026.157860

Gracillin overcomes osimertinib resistance in NSCLC via dual inhibition of EGFR and Mcl-1

Jinzhuang Liao, Qi Liang, Xuecheng Wu, Dongyu Li, Yiwei Liu, Shuangze Han, Ruirui Wang, Pengfei Guo, Ming Yi and Wei Li

Cancer Gene Ther, 2026
DOI: 10.1038/s41417-026-01016-9

Polygonum cognatum Meissn. Ethanolic Extract Promotes Apoptosis in Ovarian Cancer Cells: Experimental and Docking Study

Ceylan Hepokur, Şeyda Akın, Sema Mısır, Naveen Kosar, Aysu Gülay Bozkurt and Okan Aykaç

ChemistrySelect, 2026, 11
DOI: 10.1002/slct.202505337

Ionic strength regulates IFT in microemulsion for extraction of botanical natural products

Mengfei Tian, Ying Liu, Jie Liu, Dongyue Tian, Jiahui Gong, Mengying Zhang, Wenxue Sun, Chunjian Zhao and Chunying Li

Journal of Molecular Liquids, 2024, 414, 126181
DOI: 10.1016/j.molliq.2024.126181

Isodeoxyelephantopin Promotes Cell Death in Triple‐Negative Breast Cancer by Blocking STAT3 Phosphorylation and Enhancing the Effectiveness of Paclitaxel

Danfeng Lin, Hui Wang, Shixi Wu and Haha Chen

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.70737