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Peptide nucleic acids in parallel orientation form invasion complexes with double-stranded DNA

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RSC Chem. Biol., 2025, 6, 1566
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Synthesis, duplex-forming properties, and enzymatic resistance of oligonucleotides containing N-acylsulfonamide linkages

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Supramolecular polyplexes from Janus peptide nucleic acids (bm-PNA-G5): self-assembled bm-PNA G-quadruplex and its tetraduplex with DNA

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Org. Biomol. Chem., 2024, 22, 6810
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Highly phosphorescent N^C^N platinum(ii)-peptide nucleic acid conjugates: synthesis, photophysical studies and hybridization behaviour

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Fluorescein-switching-based lateral flow assay for the detection of microRNAs

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Impact of charges on the hybridization kinetics and thermal stability of PNA duplexes

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Recognition of mixed-sequence double-stranded DNA regions using chimeric Invader/LNA probes

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Supramolecular co-assembly of water-soluble nucleobase-containing copolymers: bioinspired synthetic platforms towards new biomimetic materials

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Serine-γPNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA

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Dynamic exchange controls the assembly structure of nucleic-acid-peptide chimeras

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Gamma-FIT-PNAs as sensitive RNA probes

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Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology

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Molecules, 2026, 31, 523
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Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids

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γ-Amino Carboxylic Acid Modification Enhances the Efficacy of Peptide Nucleic Acids Targeting miR-221-3p in Lung Cancer Cell Lines

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Fluorescent and electrochemical paper based dual sensor for simple and low cost detection of human papillomavirus DNA without denaturation

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Sci Rep, 2025, 15
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The Impact of Secondary Structure on the Base‐Filling of N‐Methoxy‐1,3‐Oxazinane (MOANA) and N‐Methoxy‐1,3‐Oxazolidine Glycol Nucleic Acid (MOGNA) Oligonucleotides

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ChemBioChem, 2025, 26
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Development of peptide nucleic acid-based bead array technology for Bacillus cereus detection

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A fluorescent complex with peptide nucleic acids modified by boronic acid and its ligand detects target RNA in cells

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Chemistry Letters, 2024, 53
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Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection)

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JACS Au, 2023, 3, 449
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Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids

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JACS Au, 2023, 3, 1952
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Electrochemical sensor for direct HIV-1 DNA detection using ruthenium assembled on a pyrrolidinyl peptide nucleic acid-DNA hybrid

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Smart DNA sensors‐based molecular identification for cancer subtyping

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Recent research on the druggability properties of chemical modification of endogenous substances

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HuR-Targeted Small-Molecule Inhibitors─Beneficial Impact in Cancer Therapy

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Structure and lowest excitation properties of the backbone-modified GC PNA dimers

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The Application of Peptide Nucleic Acids (PNA) in the Inhibition of Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Gene Expression in a Cell-Free Transcription/Translation System

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IJMS, 2024, 25, 1463
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Peptide nucleic acid probe-assisted paper-based electrochemical biosensor for multiplexed detection of respiratory viruses

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AI-designed PNA-peptide chimera overcomes suboptimal binding for dual inhibition of viral RdRp

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European Journal of Medicinal Chemistry, 2026, 302, 118357
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Novel Small Multilamellar Liposomes Containing Large Quantities of Peptide Nucleic Acid Selectively Kill Breast Cancer Cells

Galina Proshkina, Elena Shramova, Anastasiya Ryabova, Liat Katrivas, Clelia Giannini, Daniele Malpicci, Yael Levi-Kalisman, Sergey Deyev and Alexander Kotlyar

Cancers, 2022, 14, 4806
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Rapid Synthesis of Propargyl‐γ‐Modified Peptide Nucleic Acid Monomers for Late‐Stage Functionalization of Oligomers

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Strategy for Pre-Clinical Development of Active Targeting MicroRNA Oligonucleotide Therapeutics for Unmet Medical Needs

Marc Thibonnier and Sujoy Ghosh

IJMS, 2023, 24, 7126
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Peptide Nucleic Acids (PNAs) in Antimicrobial Therapy: A Next Generation Strategy

Antonia D’Aniello, Annalisa Masi, Concetta Avitabile, Giovanni del Monaco, Michele Saviano and Maria Moccia

IJMS, 2026, 27, 1565
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Detection strategies of infectious diseases via peptide-based electrochemical biosensors

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PNA/SWCNT hybrid electrochemical platform optimized by machine learning for species-specific quantification of Bacillus cereus

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Optimisation of peptide nucleic acid (PNA) probe immobilisation by EIS for enhanced bioFET detection of miR-155

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Peptide nucleic acids: Recent advancements and future opportunities in biomedical applications

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An electrophoretic mobility shift assay with chemiluminescent readout to evaluate DNA-targeting oligonucleotide-based probes

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7-Methylguanine With a Cyclopentane Backbone: A Bright Combination for a FIT-PNA RNA Sensor

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Application of Cell-Penetrating Peptides (CPP) to Enhance the Efficacy of Antisense Peptide Nucleic Acids (PNA) Molecules Delivery

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Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

Caroline P. Shepard, Raymond G. Emehiser, Saswata Karmakar and Patrick J. Hrdlicka

Molecules, 2022, 28, 127
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Gemdimethyl Peptide Nucleic Acids (α/β/γ-gdm-PNA): E/Z-Rotamers Influence the Selectivity in the Formation of Parallel/Antiparallel gdm-PNA:DNA/RNA Duplexes

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ACS Omega, 2022, 7, 40558
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Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes

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ACS Omega, 2024, 9, 45147
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Enhancing RNA inhibitory activity using clamp-G-modified nucleobases

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Cell Reports Physical Science, 2024, 5, 102120
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PNA-SERS biosensor for label-free detection of SARS-CoV-2 genomic sequences in saliva

Alessandro Esposito, Sara Martino, Deniz Yilmaz, Maria Mangini, Luca De Stefano, Annunziata Corteggio, Paola Italiani, Ilaria Rea and Anna Chiara De Luca

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High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Giorgia Danti, Linda Popella, Jörg Vogel and Hans M. Maric

Advanced Science, 2025, 12
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Evaluation of Peptide Nucleic Acid Encapsulation in Ferritin Nanocages for Gene Silencing Applications

Andrea Patrizia Falanga, Maria Vittoria Farina, Gabriele Cianfoni, Lorenzo Barolo, Chiara Di Meo, Giulia Elizabeth Borsatti, Francesca Ghirga, Bruno Botta, Luca Pisano, Nicola Borbone, Stefano D’Errico, Alessio Paone, Giorgia Oliviero, Deborah Quaglio and Paola Baiocco

Biomacromolecules, 2025, 26, 8040
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Roles and applications of peptide nucleic acid-loaded nanoparticles in cancer

Natasha Shah, Suganthi Vedanayagam, Smith Raymonde, Kevin Ramirez Garcia, Heba A. Eassa and Anisha Gupta

Nanomedicine, 2026, 21, 869
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Peptide Nucleic Acids: From Origami to Editing

Liam M. Carson and Emma E. Watson

ChemPlusChem, 2024, 89
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Comparative analysis of gamma peptide nucleic acid variants in targeting chromosomal DNA

Ruchi Ruchi and Raman Bahal

Cell Reports Physical Science, 2026, 103255
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A Visual Compendium of Principal Modifications within the Nucleic Acid Sugar Phosphate Backbone

Daria Novikova, Aleksandra Sagaidak, Svetlana Vorona and Vyacheslav Tribulovich

Molecules, 2024, 29, 3025
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Gene editing using gamma modified PNA: HBB gene as a model

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Journal of Genetic Engineering and Biotechnology, 2025, 23, 100562
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