Paper-based microfluidics in sweat detection: from design to application

Zhichao Ye, Yuyang Yuan, Shaowei Zhan, Wei Liu, Lu Fang and Tianyu Li

Analyst, 2023, 148, 1175
DOI: 10.1039/D2AN01818G

Wearable microfluidic immunosensors for point-of-care detection of bio-analytes: a critical review

Emadoddin Amin Sadrabadi, Foad Soleimani, Neda Naseri, Mohsen Ghiasi Tarzi and Kobra Omidfar

J. Mater. Chem. B, 2025, 13, 8609
DOI: 10.1039/D5TB00682A

Electrochemical paper-based devices: sensing approaches and progress toward practical applications

Eka Noviana, Cynthia P. McCord, Kaylee M. Clark, Ilhoon Jang and Charles S. Henry

Lab Chip, 2020, 20, 9
DOI: 10.1039/C9LC00903E

Paper-based microfluidics for wearable soft bioelectronics

Feng Zhang, Ganggang Zhao, Qunle Ouyang, Sicheng Chen and Zheng Yan

Lab Chip, 2026, 26, 1471
DOI: 10.1039/D5LC00754B

Discretised microfluidics for noninvasive health monitoring using sweat sensing

Emma J. M. Moonen, Walther Verberne, Eduard Pelssers, Jason Heikenfeld and Jaap M. J. den Toonder

Lab Chip, 2024, 24, 5304
DOI: 10.1039/D4LC00763H

Improving design features and air bubble manipulation techniques for a single-step sandwich electrochemical ELISA incorporating commercial electrodes into capillary-flow driven immunoassay devices

Phuritat Kaewarsa, Melissa S. Schenkel, Kira L. Rahn, Wanida Laiwattanapaisal and Charles S. Henry

Analyst, 2024, 149, 2034
DOI: 10.1039/D3AN01704D

A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action

Taher Abbasiasl, Fariborz Mirlou, Emin Istif, Hatice Ceylan Koydemir and Levent Beker

Sens. Diagn., 2022, 1, 775
DOI: 10.1039/D2SD00032F

Wearable biochemical sensors for human health monitoring: sensing materials and manufacturing technologies

Guanglei Li and Dan Wen

J. Mater. Chem. B, 2020, 8, 3423
DOI: 10.1039/C9TB02474C

Exploring the role of microfluidic paper-based analytical devices in salivary diagnostics: from concept to clinical applications

Lucas R. Sousa, Larissa G. Velasco, Sandra G. Vlachovsky, Federico Figueredo, Eduardo Cortón and Wendell K. T. Coltro

Analyst, 2026
DOI: 10.1039/D5AN01316J

Electrochemical paper-based analytical devices: ten years of development

Vanessa N. Ataide, Letícia F. Mendes, Lillia I. L. M. Gama, William R. de Araujo and Thiago R. L. C. Paixão

Anal. Methods, 2020, 12, 1030
DOI: 10.1039/C9AY02350J

Non-enzymatic sweat-based glucose sensors: progress, difficulties, and prospects

P. Kirubha, B. S. Sreeja and S. Fouziya Sulthana

Sens. Diagn., 2026
DOI: 10.1039/D6SD00042H

Dermal-fluid-enabled detection platforms for non-invasive ambulatory monitoring

Asmita Veronica, Yanan Li, Yue Li, I-Ming Hsing and Hnin Yin Yin Nyein

Sens. Diagn., 2023, 2, 1335
DOI: 10.1039/D3SD00165B

Bio-inspired fractal textile device for rapid sweat collection and monitoring

Yen-Chi Chen, Siang-Sin Shan, Yu-Te Liao and Ying-Chih Liao

Lab Chip, 2021, 21, 2524
DOI: 10.1039/D1LC00328C

Wearable and implantable microfluidic technologies for future digital therapeutics

Sanghoon Lee, Won Gi Chung, Enji Kim, Eunmin Kim, Joonho Paek, Dayeon Kim, Seung Hyun An, Taekyeong Lee, Jung Ah Lim and Jang-Ung Park

Lab Chip, 2025, 25, 4508
DOI: 10.1039/D5LC00525F

Printable biosensors towards next-generation point-of-care testing: paper substrate as an example

Yaolin Liu, Sheng Lu, Zhiheng Zhang, Zhugen Yang, Xiaolin Cui and Guozhen Liu

Lab Chip, 2023, 23, 3328
DOI: 10.1039/D3LC00038A

Paper-based colorimetric sensors for point-of-care testing

Anthony Ko and Caizhi Liao

Anal. Methods, 2023, 15, 4377
DOI: 10.1039/D3AY00943B

Autonomous wearable sensing enabled by capillary microfluidics: a review

Kiran Kuruvinashetti, Amin Komeili and Amir Sanati Nezhad

Lab Chip, 2025, 25, 3879
DOI: 10.1039/D5LC00536A

Electrochemical glucose sensors in diabetes management: an updated review (2010–2020)

Hazhir Teymourian, Abbas Barfidokht and Joseph Wang

Chem. Soc. Rev., 2020, 49, 7671
DOI: 10.1039/D0CS00304B

Electrochemical paper-based microfluidic devices: A review of separation, flow analysis, and origami-inspired architectures

Lauro A. Pradela-Filho, William B. Veloso, Danielly S. Rocha, Gilberto J. Silva Junior, Bruno Ferreira and Thiago R.L.C. Paixão

Analytica Chimica Acta, 2026, 1405, 345414
DOI: 10.1016/j.aca.2026.345414

Real-Time Monitoring of Neurotransmitters in the Brain of Living Animals

Yifan Da, Shihua Luo and Yang Tian

ACS Appl. Mater. Interfaces, 2023, 15, 138
DOI: 10.1021/acsami.2c02740

Significance of nanomaterials in electrochemical glucose sensors: An updated review (2016-2020)

Ekin Sehit and Zeynep Altintas

Biosensors and Bioelectronics, 2020, 159, 112165
DOI: 10.1016/j.bios.2020.112165

Strategies for the detection of target analytes using microfluidic paper-based analytical devices

Wei Zheng, Kan Wang, Hao Xu, Chujun Zheng, Bo Cao, Qi Qin, Qinghui Jin and Daxiang Cui

Anal Bioanal Chem, 2021, 413, 2429
DOI: 10.1007/s00216-021-03213-x

Recent Advancement in Biofluid-Based Glucose Sensors Using Invasive, Minimally Invasive, and Non-Invasive Technologies: A Review

Vundrala Sumedha Reddy, Bhawana Agarwal, Zhen Ye, Chuanqi Zhang, Kallol Roy, Amutha Chinnappan, Roger J. Narayan, Seeram Ramakrishna and Rituparna Ghosh

Nanomaterials, 2022, 12, 1082
DOI: 10.3390/nano12071082

Synergistic convergence of materials and enzymes for biosensing and self-sustaining energy devices towards on-body health monitoring

Suntisak Khumngern and Itthipon Jeerapan

Commun Mater, 2024, 5
DOI: 10.1038/s43246-024-00557-6

Recent advances in microfluidic paper-based assay devices for diagnosis of human diseases using saliva, tears and sweat samples

Chin-Chung Tseng, Chia-Te Kung, Rong-Fu Chen, Ming-Hsien Tsai, How-Ran Chao, Yao-Nan Wang and Lung-Ming Fu

Sensors and Actuators B: Chemical, 2021, 342, 130078
DOI: 10.1016/j.snb.2021.130078

Challenges and perspectives in the development of paper-based lateral flow assays

Surasak Kasetsirikul, Muhammad J. A. Shiddiky and Nam-Trung Nguyen

Microfluid Nanofluid, 2020, 24
DOI: 10.1007/s10404-020-2321-z

Effect of Pyrene-1 Boronic Acid Functionalization on the Electrical Characteristics of Carbon Nanotube Field-Effect Transistor

H. Altuntas, K. Snashall, F. Oke-Altuntas, I. Jayawerdane, M. O. Tas and S. Ravi P. Silva

Electron. Mater. Lett., 2023, 19, 405
DOI: 10.1007/s13391-023-00415-6

Recent Advances in Microfluidic Paper-Based Analytical Devices toward High-Throughput Screening

Siraprapa Boobphahom, Mai Nguyet Ly, Veasna Soum, Nayoon Pyun, Oh-Sun Kwon, Nadnudda Rodthongkum and Kwanwoo Shin

Molecules, 2020, 25, 2970
DOI: 10.3390/molecules25132970

Two-Dimensional Ternary Nanocomposite-Decorated Cellulose Field Effect Transistor for Nonenzymatic Sweat Glucose Sensing

Kodiadka Ayshathil Bushra, Yoon-Bo Shim and K. Sudhakara Prasad

ACS Appl. Nano Mater., 2024, 7, 1202
DOI: 10.1021/acsanm.3c05183

Paper as an ecodesigned and smart material for sample preparation integrated with electrochemical (bio)sensors

Vincenzo Mazzaracchio, Christian Gosti, Laura Belcastro and Fabiana Arduini

Advances in Sample Preparation, 2025, 16, 100207
DOI: 10.1016/j.sampre.2025.100207

Paper-Based Screen-Printed Electrodes: A New Generation of Low-Cost Electroanalytical Platforms

Estefanía Costa-Rama and María Teresa Fernández-Abedul

Biosensors, 2021, 11, 51
DOI: 10.3390/bios11020051

Integrating Microfluidic and Biosensors: A Mini Review

Hengky Tanjaya and Christian Harito

J. Phys.: Conf. Ser., 2024, 2705, 012018
DOI: 10.1088/1742-6596/2705/1/012018

A topical review on AI-interlinked biodomain sensors for multi-purpose applications

Rubi Thapa, Sachin Poudel, Katarzyna Krukiewicz and Anil Kunwar

Measurement, 2024, 227, 114123
DOI: 10.1016/j.measurement.2024.114123

A Smartwatch Integrated with a Paper‐based Microfluidic Patch for Sweat Electrolytes Monitoring

Qingpeng Cao, Bo Liang, Xiyu Mao, Jinwei Wei, Tingting Tu, Lu Fang and Xuesong Ye

Electroanalysis, 2021, 33, 643
DOI: 10.1002/elan.202060025

Enclosed paper-based analytical devices: Concept, variety, and outlook

Chang-Ming Wang, Chong-You Chen and Wei-Ssu Liao

Analytica Chimica Acta, 2021, 1144, 158
DOI: 10.1016/j.aca.2020.10.007

Multi-dimensional microfluidic paper-based analytical devices (μPADs) for noninvasive testing: A review of structural design and applications

Ting Chen, Ce Sun, Syed Comail Abbas, Nur Alam, Sheng Qiang, Xiuzhi Tian, Chenglong Fu, Hui Zhang, Yuanyuan Xia, Liu Liu, Yonghao Ni and Xue Jiang

Analytica Chimica Acta, 2024, 1321, 342877
DOI: 10.1016/j.aca.2024.342877

Engineering strategies for enhancing the performance of electrochemical paper-based analytical devices

Mahroo Baharfar, Mohammad Rahbar, Mohammad Tajik and Guozhen Liu

Biosensors and Bioelectronics, 2020, 167, 112506
DOI: 10.1016/j.bios.2020.112506

An integrated, wearable paper microfluidic array device for multicomponent electrochemical sweat sensing

Qian Yu, Jie Wu, Wencheng Xiao, Chao Zhao, Weiqi Zhang, Yunlong Chen, Ying Liu, Hong Liu, Jun Zhou, Lin Ding and Huangxian Ju

Cell Reports Physical Science, 2025, 6, 102389
DOI: 10.1016/j.xcrp.2024.102389

Microfluidic Paper-Based Sensors and Their Applications for Glucose Sensing

Phan Gia Le and Sungbo Cho

Chemosensors, 2025, 13, 293
DOI: 10.3390/chemosensors13080293

Electrochemical Sensing Directions for Next-Generation Healthcare: Trends, Challenges, and Frontiers

Juan F. Hernández-Rodríguez, Daniel Rojas and Alberto Escarpa

Anal. Chem., 2021, 93, 167
DOI: 10.1021/acs.analchem.0c04378

Smart microfluidic devices integrated in electrochemical point-of-care platforms for biomarker detection in biological fluids

Vincenzo Mazzaracchio and Fabiana Arduini

Anal Bioanal Chem, 2026, 418, 459
DOI: 10.1007/s00216-025-06127-0

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi and Maria Sabrina Sarto

Adv Healthcare Materials, 2026
DOI: 10.1002/adhm.202504991

Quantitative analysis for sweat-absorbing times of paper-based microfluidic chips

Heyue Huang, Chuanpei Xu, Peng Long, Yanzhang Chen, Xijun Huang, Zheng Liu and Hong Yang

Microfluid Nanofluid, 2024, 28
DOI: 10.1007/s10404-023-02696-7

Recent advancement in electrode materials and fabrication, microfluidic designs, and self-powered systems for wearable non-invasive electrochemical glucose monitoring

Alireza Sanati, Yasaman Esmaeili, Elham Bidram, Laleh Shariati, Mohammad Rafienia, Sara Mahshid and Onur Parlak

Applied Materials Today, 2022, 26, 101350
DOI: 10.1016/j.apmt.2021.101350

Printed Devices for Wearable Biosensors: Laboratory to Emerging Markets

Itthipon Jeerapan and Suntisak Khumngern

IEEE Flex. Electron., 2023, 2, 358
DOI: 10.1109/JFLEX.2023.3272624

Wearable Analytical Platform with Enzyme-Modulated Dynamic Range for the Simultaneous Colorimetric Detection of Sweat Volume and Sweat Biomarkers

Andreu Vaquer, Enrique Barón and Roberto de la Rica

ACS Sens., 2021, 6, 130
DOI: 10.1021/acssensors.0c01980

A portable microfluidic electrochemical sensing platform for rapid detection of hazardous metal Pb2+ based on thermocapillary convection using 3D Ag-rGO-f-Ni(OH)2/NF as a signal amplifying element

Shangshang Ma, Wei Zhao, Qing Zhang, Keying Zhang, Chong Liang, Dingkai Wang, Xutang Liu and Xijie Zhan

Journal of Hazardous Materials, 2023, 448, 130923
DOI: 10.1016/j.jhazmat.2023.130923

Progress in paper-based analytical devices for climate neutral biosensing

Anshuman Mishra, Santanu Patra, Vaibhav Srivastava, Lokman Uzun, Yogendra Kumar Mishra, Mikael Syväjärvi and Ashutosh Tiwari

Biosensors and Bioelectronics: X, 2022, 11, 100166
DOI: 10.1016/j.biosx.2022.100166

Electrochemical Nanosensors for Sensitization of Sweat Metabolites: From Concept Mapping to Personalized Health Monitoring

Riyanka Das, Somrita Nag and Priyabrata Banerjee

Molecules, 2023, 28, 1259
DOI: 10.3390/molecules28031259

Surface Wettability for Skin‐Interfaced Sensors and Devices

Xiufeng Wang, Yangchengyi Liu, Huanyu Cheng and Xiaoping Ouyang

Adv Funct Materials, 2022, 32
DOI: 10.1002/adfm.202200260

Modelling Prospects of Bio-Electrochemical Immunosensing Platforms

Mansi Gandhi

Electrochem, 2024, 5, 146
DOI: 10.3390/electrochem5020010

A PEDOT:PSS conductive hydrogel incorporated with Prussian blue nanoparticles for wearable and noninvasive monitoring of glucose

Changshun Xu, Danfeng Jiang, Yuancai Ge, Liping Huang, Yang Xiao, Xueqian Ren, Xiaohu Liu, Qingwen Zhang and Yi Wang

Chemical Engineering Journal, 2022, 431, 134109
DOI: 10.1016/j.cej.2021.134109

Recent Advances in Wearable Sweat Sensor Development

Tao Zhang, Giraso Keza Monia Kabandana, John A. Terrell, Hui Chen and Chengpeng Chen

WIREs Nanomed Nanobiotechnol, 2025, 17
DOI: 10.1002/wnan.70006

Wearable Healthcare Monitoring Based on a Microfluidic Electrochemical Integrated Device for Sensing Glucose in Natural Sweat

Zouaghi Noura, Imran Shah, Shahid Aziz, Aamouche Ahmed, Dong-Won Jung, Lakssir Brahim and Ressami ElMostafa

Sensors, 2022, 22, 8971
DOI: 10.3390/s22228971

Paper‐based Wearable Electrochemical Sensors: A New Generation of Analytical Devices

Patricia Batista Deroco, Dagwin Wachholz Junior and Lauro Tatsuo Kubota

Electroanalysis, 2023, 35
DOI: 10.1002/elan.202200177

Emerging trends in miniaturized and microfluidic electrochemical sensing platforms

Jaligam Murali Mohan, Khairunnisa Amreen, Arshad Javed, Satish Kumar Dubey and Sanket Goel

Current Opinion in Electrochemistry, 2022, 33, 100930
DOI: 10.1016/j.coelec.2021.100930

An up-conversion test paper based on “switch-off” of fluorescence is constructed to sensitively and selectively detect cancer-causing dye Sudan III in lipstick

Tian Shi, Zhiyuan Cheng, Tong Liu, Zhiqi Ye and Yueli Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 280, 121515
DOI: 10.1016/j.saa.2022.121515

Addressing the sample volume dependency of the colorimetric glucose measurement on microfluidic paper-based and thread/paper-based analytical devices using a novel low-cost analytical viewpoint

Mohammad Derakhshani, Amir Jahanshahi and Hedayatollah Ghourchian

Microchemical Journal, 2023, 195, 109545
DOI: 10.1016/j.microc.2023.109545

An Integrated Paper‐Based Patch for Wearable Detection of Diabetic Nephropathy Biomarkers in Sweat

Shanshan Zhang, Hongfeng Wang, Yuke Zheng, Yelan Yao, Tianyu Li, Yukun Ma, Yue Zhou, Zhiyang Chen, Yiming Wei, Lu Fang, Xiangmei Chen, Xuesong Ye, Jianhui Zhou and Bo Liang

Adv Funct Materials, 2025, 35
DOI: 10.1002/adfm.202501970

Electrospun nanofiber-based glucose sensors for glucose detection

Yutong Du, Xinyi Zhang, Ping Liu, Deng-Guang Yu and Ruiliang Ge

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.944428

Printed Electrochemical Biosensors: Opportunities and Metrological Challenges

Emilio Sardini, Mauro Serpelloni and Sarah Tonello

Biosensors, 2020, 10, 166
DOI: 10.3390/bios10110166

Recent advances in wearable electrochemical biosensors towards technological and material aspects

Mahan Hosseinzadeh Fakhr, Ivan Lopez Carrasco, Dmitry Belyaev, Jihun Kang, YeHyeon Shin, Jong-Souk Yeo, Won-Gun Koh, Jeongwoo Ham, Alexander Michaelis, Joerg Opitz and Natalia Beshchasna

Biosensors and Bioelectronics: X, 2024, 19, 100503
DOI: 10.1016/j.biosx.2024.100503

Dual-signal readout paper-based wearable biosensor with a 3D origami structure for multiplexed analyte detection in sweat

Yuemeng Cheng, Shaoqing Feng, Qihong Ning, Tangan Li, Hao Xu, Qingwen Sun, Daxiang Cui and Kan Wang

Microsyst Nanoeng, 2023, 9
DOI: 10.1038/s41378-023-00514-2

Electrochemical Sweat Sensors

Emanuel Bilbao, Octavio Garate, Theo Rodríguez Campos, Mariano Roberti, Mijal Mass, Alex Lozano, Gloria Longinotti, Leandro Monsalve and Gabriel Ybarra

Chemosensors, 2023, 11, 244
DOI: 10.3390/chemosensors11040244

The use of biological fluids in microfluidic paper-based analytical devices (μPADs): Recent advances, challenges and future perspectives

Laís Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jéssica Rocha Camargo, Bruno Campos Janegitz and Emanuel Carrilho

Biosensors and Bioelectronics, 2024, 246, 115846
DOI: 10.1016/j.bios.2023.115846

The rise of eco-friendly electronics: Exploring wearable paper-based electroanalytical devices

Joseph Benjamin Holman, Ayobami Elisha Oseyemi, Mkliwa Koumbia, Zhengdi Shi, Chengpan Li and Weiping Ding

Materials Science and Engineering: R: Reports, 2025, 163, 100939
DOI: 10.1016/j.mser.2025.100939

A novel low-cost and simple fabrication technique for a paper-based analytical device using super glue

Hyo-eun Kang, The Huy Bui, Won Han, Yong-Ill Lee and Joong Ho Shin

Analytica Chimica Acta, 2024, 1329, 343174
DOI: 10.1016/j.aca.2024.343174

Wearable Janus nanofiber membrane-based colorimetric sensors for directional transfer and analysis of sweat

Xuecui Mei, Liang Zhu, Xin Peng, Jiao Yang and Yingchun Li

Biomedical Analysis, 2024, 1, 64
DOI: 10.1016/j.bioana.2024.02.002

Screen-Printed Electrodes: Promising Paper and Wearable Transducers for (Bio)Sensing

Paloma Yáñez-Sedeño, Susana Campuzano and José Manuel Pingarrón

Biosensors, 2020, 10, 76
DOI: 10.3390/bios10070076

Wearable Sweat Management Technologies

Lei Wei, Zhen Li, Zongxian Dai, Lihua Ding, Hongjian Wei, Jun Li, Hui Zhu and Yong Zhu

Adv Materials Technologies, 2024, 9
DOI: 10.1002/admt.202301812

Wearable Microfluidics for Continuous Assay

Pei-Heng Lin, Hsin-Hua Nien and Bor-Ran Li

Annual Rev. Anal. Chem., 2023, 16, 181
DOI: 10.1146/annurev-anchem-091322-082930

Le Minh Tu Phan, Thuy Anh Thu Vo, Thi Xoan Hoang, Sathish Panneer Selvam, Hoang Lan Pham, Jae Young Kim and Sungbo Cho

Adv Materials Technologies, 2021, 6
DOI: 10.1002/admt.202100020

Flexible cellulose paper-based biosensor from inkjet printing for non-invasive glucose monitoring

Binghuan Zhang, Liyuan Wang, Shwu-Jen Chang, Yanzhen Jing, Tianyi Sun, Ziang Lei, Ching-Jung Chen and Jen-Tsai Liu

Polymer Testing, 2024, 137, 108527
DOI: 10.1016/j.polymertesting.2024.108527

An Integrated Paper-Based Microfluidic Device for Real-Time Sweat Potassium Monitoring

Bo Liang, Qingpeng Cao, Xiyu Mao, Wenhao Pan, Tingting Tu, Lu Fang and Xuesong Ye

IEEE Sensors J., 2021, 21, 9642
DOI: 10.1109/JSEN.2020.3009327

Research Progress and Prospects of Intelligent Diabetes Monitoring Systems: A Review

Yuanyuan Zou, Zhengkang Chu, Tongyan Yang, Jinhong Guo and Diangeng Li

IEEE Sensors J., 2024, 24, 23401
DOI: 10.1109/JSEN.2024.3411570

Microfluidic wearable electrochemical sweat sensors for health monitoring

Balaji Ramachandran and Ying-Chih Liao

Biomicrofluidics, 2022, 16
DOI: 10.1063/5.0116648

Enzyme-based and enzyme-free metal-based glucose biosensors: Classification and recent advances

Seyed Saman Nemati, Gholamreza Dehghan, Samaneh Rashtbari, Tran Nhat Tan and Alireza Khataee

Microchemical Journal, 2023, 193, 109038
DOI: 10.1016/j.microc.2023.109038

A Portable 3D Microfluidic Origami Biosensor for Cortisol Detection in Human Sweat

Xuan Weng, Zhuoyi Fu, Cheng Zhang, Wen Jiang and Hai Jiang

Anal. Chem., 2022, 94, 3526
DOI: 10.1021/acs.analchem.1c04508

Electrochemical biosensor employing PbS colloidal quantum dots/Au nanospheres-modified electrode for ultrasensitive glucose detection

Yunong Zhao, Jing Huang, Qing Huang, Yanbing Tao, Ruiqin Gu, Hua-Yao Li and Huan Liu

Nano Res., 2023, 16, 4085
DOI: 10.1007/s12274-022-5138-0

Eco-sustainable point-of-care devices: Progress in paper and fabric based electrochemical and colorimetric biosensors

P. Lingadharini and Debashis Maji

Talanta, 2025, 285, 127397
DOI: 10.1016/j.talanta.2024.127397

Molecularly imprinted polymer grafted on paper and flat sheet for selective sensing and diagnosis: a review

Zahra Mamipour, Ali Nematollahzadeh and Mohsen Kompany-Zareh

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-04930-x

State of the art Overview wearable microfluidic noninvasive biomarker sensors for sweat analysis

Chen Liu, Xu Sun, Qingfeng Wang, Siqi Wang, Qianqian Wang and Sheng Zhang

Microchemical Journal, 2025, 209, 112847
DOI: 10.1016/j.microc.2025.112847

Paper-Based Enzymatic Electrochemical Sensors for Glucose Determination

Olaya Amor-Gutiérrez, Estefanía Costa-Rama and M. Teresa Fernández-Abedul

Sensors, 2022, 22, 6232
DOI: 10.3390/s22166232

Sustainable and scalable detection: Paper-based analytical devices and miniaturized detection systems for modern diagnostics

Ahmed Isa, Mahdi Gharibi, Ahmet Cetinkaya and Sibel A. Ozkan

Microchemical Journal, 2025, 212, 113210
DOI: 10.1016/j.microc.2025.113210

Microfluidics and electrochemistry: an emerging tandem for next-generation analytical microsystems

Ana Fernández-la-Villa, Diego F. Pozo-Ayuso and Mario Castaño-Álvarez

Current Opinion in Electrochemistry, 2019, 15, 175
DOI: 10.1016/j.coelec.2019.05.014

Microfluidic integration for electrochemical biosensor applications

Leona M. Schmidt-Speicher and Kerstin Länge

Current Opinion in Electrochemistry, 2021, 29, 100755
DOI: 10.1016/j.coelec.2021.100755

An integrated and conductive hydrogel-paper patch for simultaneous sensing of Chemical–Electrophysiological signals

Tianyu Li, Bo Liang, Zhichao Ye, Lei Zhang, Shiyi Xu, Tingting Tu, Yiming Zhang, Yu Cai, Bin Zhang, Lu Fang, Xiyu Mao, Shanshan Zhang, Guan Wu, Qifu Yang, Congcong Zhou, Xiujun Cai and Xuesong Ye

Biosensors and Bioelectronics, 2022, 198, 113855
DOI: 10.1016/j.bios.2021.113855

Directional sweat transport window based on hydrophobic/hydrophilic Janus fabric enables continuous transfer and monitoring of sweat

Zicao Peng, Riping Liu, Zhiguang Xu, Huanjie Chi, Zhong Wang and Yan Zhao

Applied Materials Today, 2022, 29, 101623
DOI: 10.1016/j.apmt.2022.101623

Component optimization in optical and electrochemical paper-based analytical devices

Rahmatollah Zarezadeh Mehrizi, Marjan Majdinasab, Mohammad Hadi Eskandari and Hassan Mozaffari-Khosravi

Clinica Chimica Acta, 2026, 578, 120571
DOI: 10.1016/j.cca.2025.120571

Easy-to-Fabricate Digital Microfluidic Chip Based on PCB With Glucose Enzyme-Free Detection Function

Heyue Huang, Chuanpei Xu, Tao Zhan, Siyu Li, Guo-Cheng Han, Bo Zhang and Yuanyin Cen

IEEE Sensors J., 2025, 25, 43522
DOI: 10.1109/JSEN.2025.3622368

Do-it-yourself screen printing of electrochemical paper-based analytical devices with water treatment and sandwiched electrodes for amplified signal

Seyed Hamid Safiabadi Tali, Rozhin Saebi, Abdolali Mehrjou, Farzad Mirzaie, Zubi Sadiq, Marc-Antoni Goulet and Sana Jahanshahi-Anbuhi

Electrochimica Acta, 2026, 548, 147931
DOI: 10.1016/j.electacta.2025.147931

Skin-interfaced colorimetric microfluidic devices for on-demand sweat analysis

Weiyi Liu, Huanyu Cheng and Xiufeng Wang

npj Flex Electron, 2023, 7
DOI: 10.1038/s41528-023-00275-y

Current Trends in the Development of Electrochemical Biosensor for Detecting Analytes from Sweat

Anoop Singh, Asha Sharma, Aman Dubey and Sandeep Arya

CMC, 2024, 31, 3882
DOI: 10.2174/0929867331666230807143639

3D Origami-Inspired Electrochemical Paper-Based Analytical Devices with Flow-Through Electrodes and Quasi-Steady Flow

Yang Wang, Dingding Ye, Yang Xu, Xun Zhu, Yang Yang, Rong Chen and Qiang Liao

Ind. Eng. Chem. Res., 2024, 63, 8786
DOI: 10.1021/acs.iecr.3c04520

Minimally invasive electrochemical continuous glucose monitoring sensors: Recent progress and perspective

Yuanyuan Zou, Zhengkang Chu, Jiuchuan Guo, Shan Liu, Xing Ma and Jinhong Guo

Biosensors and Bioelectronics, 2023, 225, 115103
DOI: 10.1016/j.bios.2023.115103

Wearable flexible microfluidic sensing technologies

Shuwen Chen, Zheng Qiao, Yan Niu, Joo Chuan Yeo, Yuanchao Liu, Jiaming Qi, Shicheng Fan, Xiaoyan Liu, Jee Yeon Lee and Chwee Teck Lim

Nat Rev Bioeng, 2023, 1, 950
DOI: 10.1038/s44222-023-00094-w

Microfluidic-Based Non-Invasive Wearable Biosensors for Real-Time Monitoring of Sweat Biomarkers

Seyedeh Rojin Shariati Pour, Donato Calabria, Afsaneh Emamiamin, Elisa Lazzarini, Andrea Pace, Massimo Guardigli, Martina Zangheri and Mara Mirasoli

Biosensors, 2024, 14, 29
DOI: 10.3390/bios14010029

Wearable Chemical Sensors: Emerging Systems for On-Body Analytical Chemistry

Juliane R. Sempionatto, Itthipon Jeerapan, Sadagopan Krishnan and Joseph Wang

Anal. Chem., 2020, 92, 378
DOI: 10.1021/acs.analchem.9b04668

Spatial and temporal detection of root exudates with a paper-based microfluidic device

Daniel Patko, Udara Bimendra Gunatilake, Belen Gonzalez-Gaya, Lionel X. Dupuy, Lourdes Basabe-Desmonts and Fernando Benito-Lopez

Soil Biology and Biochemistry, 2024, 195, 109456
DOI: 10.1016/j.soilbio.2024.109456

Microfluidic Paper-based Device for Medicinal Diagnosis

Atchara Lomae, Pattarachaya Preechakasedkit, Kanyapat Teekayupak, Yosita Panraksa, Jutiporn Yukird, Orawon Chailapakul and Nipapan Ruecha

CTMC, 2022, 22, 2282
DOI: 10.2174/1568026623666221103103211

Advancements in glucose biosensors: Innovations for wearable and real-time monitoring

Reetu Singh, Priyanshu Nema, Arpana Purohit, Satyamshyam Vishwakarma, Shyamji Tantuway, Pradhumn Namdeo, Ajay Kumar, Vandana Soni and Sushil Kumar Kashaw

Talanta, 2026, 299, 129045
DOI: 10.1016/j.talanta.2025.129045

Disposable electrodes from waste materials and renewable sources for (bio)electroanalytical applications

Giulia Moro, Fabio Bottari, Joren Van Loon, Els Du Bois, Karolien De Wael and Ligia Maria Moretto

Biosensors and Bioelectronics, 2019, 146, 111758
DOI: 10.1016/j.bios.2019.111758

Wearable electrochemical sensors for forensic and clinical applications

Patrick Cesar Ferreira, Vanessa Neiva Ataíde, Cyro Lucas Silva Chagas, Lúcio Angnes, Wendell Karlos Tomazelli Coltro, Thiago Regis Longo Cesar Paixão and William Reis de Araujo

TrAC Trends in Analytical Chemistry, 2019, 119, 115622
DOI: 10.1016/j.trac.2019.115622

Air-permeable electrode for highly sensitive and noninvasive glucose monitoring enabled by graphene fiber fabrics

Shengying Cai, Changshun Xu, Danfeng Jiang, Meiling Yuan, Qingwen Zhang, Zhaoling Li and Yi Wang

Nano Energy, 2022, 93, 106904
DOI: 10.1016/j.nanoen.2021.106904

Recent Progress in Wearable Biosensors: From Healthcare Monitoring to Sports Analytics

Shun Ye, Shilun Feng, Liang Huang and Shengtai Bian

Biosensors, 2020, 10, 205
DOI: 10.3390/bios10120205

A novel photolithographic method for fabrication of flexible micro-patterned glucose sensors

Donghee Ma, Seunghwan Chon, Sooho Cho, Youngkeun Lee, Minsoo Yoo, Dongok Kim, Dong Yeop Lee and Jung Ku Lim

Journal of Electroanalytical Chemistry, 2020, 876, 114720
DOI: 10.1016/j.jelechem.2020.114720

Performance Testing of Paper-based Electrochemical Sensor for Blood pH Measurements

Xingxing Cheng, Changlong He, Wei Zhang, Huijin Wan, Qiuna Shi and Huilin Liu

International Journal of Electrochemical Science, 2022, 17, 221259
DOI: 10.20964/2022.12.57

Non‐enzyme electrochemical sensing fabrics and wearable applications based on bimetallic NiCo‐MOFs

Mengxian Yuan, Lichao Wang, Kerui Li, Qinghong Zhang, Yaogang Li, Chengyi Hou and Hongzhi Wang

Electroanalysis, 2023, 35
DOI: 10.1002/elan.202200556

Wearable Electrochemical Glucose Sensors in Diabetes Management: A Comprehensive Review

Tamoghna Saha, Rafael Del Caño, Kuldeep Mahato, Ernesto De la Paz, Chuanrui Chen, Shichao Ding, Lu Yin and Joseph Wang

Chem. Rev., 2023, 123, 7854
DOI: 10.1021/acs.chemrev.3c00078

Recent advances and perspectives in sweat based wearable electrochemical sensors

A.M.Vinu Mohan, Vinoth Rajendran, Rupesh K. Mishra and Mathiyarasu Jayaraman

TrAC Trends in Analytical Chemistry, 2020, 131, 116024
DOI: 10.1016/j.trac.2020.116024

Composite Nanofiber Membrane-Based Microfluidic Fluorescence Sensors for Sweat Analysis

Xuecui Mei, Lei Zhou, Liang Zhu and Bin Wang

Anal. Chem., 2025, 97, 492
DOI: 10.1021/acs.analchem.4c04616

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Lanka Tata Rao, Chandan Kumar Mandal and Fernando Patolsky

Adv Healthcare Materials, 2026, 15
DOI: 10.1002/adhm.202503096

Recent advances on paper-based microfluidic devices for bioanalysis

Habdias A. Silva-Neto, Iana V.S. Arantes, André L. Ferreira, Guida H.M. do Nascimento, Gabriel N. Meloni, William R. de Araujo, Thiago R.L.C. Paixão and Wendell K.T. Coltro

TrAC Trends in Analytical Chemistry, 2023, 158, 116893
DOI: 10.1016/j.trac.2022.116893

Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

Antonio Espinosa, Joannes Diaz, Edgar Vazquez, Lina Acosta, Arianna Santiago and Lisandro Cunci

Talanta Open, 2022, 6, 100142
DOI: 10.1016/j.talo.2022.100142

Wearable microfluidic patch with integrated capillary valves and pumps for sweat management and multiple biomarker analysis

Hengjie Zhang, Ye Qiu, Sihang Yu, Chen Ding, Jiahui Hu, Hangcheng Qi, Ye Tian, Zheng Zhang, Aiping Liu and Huaping Wu

Biomicrofluidics, 2022, 16
DOI: 10.1063/5.0092084

Fundamental Study of a Wristwatch Sweat Lactic Acid Monitor

Sakae Konno and Hiroyuki Kudo

Biosensors, 2024, 14, 187
DOI: 10.3390/bios14040187

Paper‐Based Electronics: Toward Sustainable Electronics

Sonia Gomez‐Gijon, Inmaculada Ortiz‐Gómez and Almudena Rivadeneyra

Advanced Sustainable Systems, 2025, 9
DOI: 10.1002/adsu.202400486

Microfluidic Paper-Based Analytical Devices: From Design to Applications

Eka Noviana, Tugba Ozer, Cody S. Carrell, Jeremy S. Link, Catherine McMahon, Ilhoon Jang and Charles S. Henry

Chem. Rev., 2021, 121, 11835
DOI: 10.1021/acs.chemrev.0c01335

Continuous Flow Synthesis of N-Doped Carbon Quantum Dots for Total Phenol Content Detection

Shangxin Guo, Jing Lan, Bo Liu, Baixiu Zheng, Xingchu Gong and Xiaohui Fan

Chemosensors, 2022, 10, 334
DOI: 10.3390/chemosensors10080334

Biomedical Applications of Microfluidic Devices: A Review

Ghazaleh Gharib, İsmail Bütün, Zülâl Muganlı, Gül Kozalak, İlayda Namlı, Seyedali Seyedmirzaei Sarraf, Vahid Ebrahimpour Ahmadi, Erçil Toyran, Andre J. van Wijnen and Ali Koşar

Biosensors, 2022, 12, 1023
DOI: 10.3390/bios12111023

Multifunctional nanomaterials for smart wearable diabetic healthcare devices

Tae Yeon Kim, Ranjit De, Inhoo Choi, Hyemin Kim and Sei Kwang Hahn

Biomaterials, 2024, 310, 122630
DOI: 10.1016/j.biomaterials.2024.122630

A Noninvasive Sweat Glucose Biosensor Based on Glucose Oxidase/Multiwalled Carbon Nanotubes/Ferrocene-Polyaniline Film/Cu Electrodes

Yanfang Guan, Lei Liu, Shaobo Yu, Feng Lv, Mingshuo Guo, Qing Luo, Shukai Zhang, Zongcai Wang, Lan Wu, Yang Lin and Guangyu Liu

Micromachines, 2022, 13, 2142
DOI: 10.3390/mi13122142

Non-invasive wearable chemical sensors in real-life applications

Nadtinan Promphet, Sarute Ummartyotin, Wittaya Ngeontae, Pumidech Puthongkham and Nadnudda Rodthongkum

Analytica Chimica Acta, 2021, 1179, 338643
DOI: 10.1016/j.aca.2021.338643

Highly Sensitive Enzyme-Free Electrochemical Sensor based on Ni(OH)2/C Composite for the Detection of Blood Glucose

Ping Wang

International Journal of Electrochemical Science, 2022, 17, 221010
DOI: 10.20964/2022.10.05

A low-cost and simple-fabricated epidermal sweat patch based on “cut-and-paste” manufacture

Teng Sun, Jianan Hui, Lin Zhou, Bo Lin, Hebin Sun, Yanan Bai, Jianlong Zhao and Hongju Mao

Sensors and Actuators B: Chemical, 2022, 368, 132184
DOI: 10.1016/j.snb.2022.132184

Hybrid Janus Membrane with Dual-Asymmetry Integration of Wettability and Conductivity for Ultra-Low-Volume Sweat Sensing

Xiao Hong, Huimin Wu, Chengcheng Wang, Xinran Zhang, Chenjie Wei, Zhikang Xu, Dajing Chen and Xiaojun Huang

ACS Appl. Mater. Interfaces, 2022, 14, 9644
DOI: 10.1021/acsami.1c16820

An inexpensive, high-throughput μPAD assay of microbial growth rate and motility on solid surfaces using Saccharomyces cerevisiae and Escherichia coli as model organisms

Alyssa Francesca Levy, Anthony Labrador, Leslie Knecht, J. David Van Dyken and David T. Eddington

PLoS ONE, 2020, 15, e0225020
DOI: 10.1371/journal.pone.0225020

Craft-and-Stick Xurographic Manufacturing of Integrated Microfluidic Electrochemical Sensing Platform

Supatinee Kongkaew, Lingyin Meng, Warakorn Limbut, Guozhen Liu, Proespichaya Kanatharana, Panote Thavarungkul and Wing Cheung Mak

Biosensors, 2023, 13, 446
DOI: 10.3390/bios13040446

Principles of long-term fluids handling in paper-based wearables with capillary–evaporative transport

Timothy Shay, Tamoghna Saha, Michael D. Dickey and Orlin D. Velev

Biomicrofluidics, 2020, 14
DOI: 10.1063/5.0010417

Advanced Wearable Microfluidic Sensors for Healthcare Monitoring

Sheng Li, Zhong Ma, Zhonglin Cao, Lijia Pan and Yi Shi

Small, 2020, 16
DOI: 10.1002/smll.201903822

A Wearable Patch Sensor for Simultaneous Detection of Dopamine and Glucose in Sweat

Yue Sun, Junjie Ma, Yuwei Wang, Sen Qiao, Yihao Feng, Zhanhong Li, Zifeng Wang, Yutong Han and Zhigang Zhu

Analytica, 2023, 4, 170
DOI: 10.3390/analytica4020014

Rapid segmentation and sensitive analysis of CRP with paper-based microfluidic device using machine learning

Qihong Ning, Wei Zheng, Hao Xu, Armando Zhu, Tangan Li, Yuemeng Cheng, Shaoqing Feng, Li Wang, Daxiang Cui and Kan Wang

Anal Bioanal Chem, 2022, 414, 3959
DOI: 10.1007/s00216-022-04039-x

Application of the Non-Enzymatic Glucose Sensor Combined with Microfluidic System and Calibration Readout Circuit

Jung-Chuan Chou, Yu-Hao Huang, Po-Yu Kuo, Chih-Hsien Lai, Yu-Hsun Nien, Yung-Yu Chen, Zhi-Xuan Kang and Kun-Tse Lee

Chemosensors, 2021, 9, 351
DOI: 10.3390/chemosensors9120351

Recent Advances in In Vivo Neurochemical Monitoring

Chao Tan, Elaine M. Robbins, Bingchen Wu and Xinyan Tracy Cui

Micromachines, 2021, 12, 208
DOI: 10.3390/mi12020208

Hybrid Technologies Combining Solid-State Sensors and Paper/Fabric Fluidics for Wearable Analytical Devices

Meritxell Rovira, César Fernández-Sánchez and Cecilia Jiménez-Jorquera

Biosensors, 2021, 11, 303
DOI: 10.3390/bios11090303

Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices

Zarfashan Shahid, Kornautchaya Veenuttranon, Xianbo Lu and Jiping Chen

Biosensors, 2024, 14, 561
DOI: 10.3390/bios14110561