A light-induced hydrogel responsive platform to capture and selectively isolate single circulating tumor cells

Bei Chen, Ganggang Wang, Chunyu Huang, Yue Sun, Jing Zhang, Zhuomin Chai, Shi-Shang Guo, Xing-Zhong Zhao, Yufeng Yuan and Wei Liu

Nanoscale, 2022, 14, 3504
DOI: 10.1039/D1NR06876H

Improving single-cell transcriptome sequencing efficiency with a microfluidic phase-switch device

Baoyue Zhang, Hong Xu, Yuqing Huang, Weiliang Shu, Hongtao Feng, Jin Cai, Jiang F. Zhong and Yan Chen

Analyst, 2019, 144, 7185
DOI: 10.1039/C9AN00823C

Tailored point-of-care biosensors for liquid biopsy in the field of oncology

Sima Singh, Pritam Saha Podder, Matt Russo, Charles Henry and Stefano Cinti

Lab Chip, 2023, 23, 44
DOI: 10.1039/D2LC00666A

DNA Hydrogels for Cancer Diagnosis and Therapy

Li Peng, Shuang Gu, Min Hou and Xiaohua Hou

ChemBioChem, 2024, 25
DOI: 10.1002/cbic.202400494

Pairing Microwell Arrays with an Affordable, Semiautomated Single-Cell Aspirator for the Interrogation of Circulating Tumor Cell Heterogeneity

Jacob J. Tokar, Charlotte N. Stahlfeld, Jamie M. Sperger, David J. Niles, David J. Beebe, Joshua M. Lang and Jay W. Warrick

SLAS Technology, 2020, 25, 162
DOI: 10.1177/2472630319898146

Hydrogel-based technologies in liquid biopsy for the detection of circulating clinical markers: challenges and prospects

Young Jun Kim and Junhong Min

Anal Bioanal Chem, 2024, 416, 2065
DOI: 10.1007/s00216-023-05025-7

Efficient Detection and Single-Cell Extraction of Circulating Tumor Cells in Peripheral Blood

Rui Li, Zhiyi Gong, Kezhen Yi, Wei Li, Yichao Liu, Fubing Wang and Shi-shang Guo

ACS Appl. Bio Mater., 2020, 3, 6521
DOI: 10.1021/acsabm.0c00957

Sequence-Based Platforms for Discovering Biomarkers in Liquid Biopsy of Non-Small-Cell Lung Cancer

Liam J. Brockley, Vanessa G. P. Souza, Aisling Forder, Michelle E. Pewarchuk, Melis Erkan, Nikita Telkar, Katya Benard, Jessica Trejo, Matt D. Stewart, Greg L. Stewart, Patricia P. Reis, Wan L. Lam and Victor D. Martinez

Cancers, 2023, 15, 2275
DOI: 10.3390/cancers15082275

Advances in Single-Cell Techniques for Linking Phenotypes to Genotypes

Hsiao-Chun Chen, Yushu Ma, Jinxiong Cheng and Yu-Chih Chen

CANCER HETEROG PLAST, 2024, 1
DOI: 10.47248/chp2401010004

Circulating tumor cell profiling for precision oncology

Mahmoud Labib and Shana O. Kelley

Molecular Oncology, 2021, 15, 1622
DOI: 10.1002/1878-0261.12901

High‐Viability Circulating Tumor Cells Sorting From Whole Blood at Single Cell Level Using Laser‐Induced Forward Transfer‐Assisted Microfiltration

Qingmei Xu, Yuntong Wang, Songtao Dou, Yang Xu, Zhenhe Xu, Han Xu, Yi Zhang, Yanming Xia, Ying Xue, Hang Li, Xiao Ma, Kunlong Zhang, Huan Wang, Fengzhou Ma, Qi Wang, Bei Li and Wei Wang

Advanced Science, 2025, 12
DOI: 10.1002/advs.202414195

An Integrated Microfluidic Chip and Its Clinical Application for Circulating Tumor Cell Isolation and Single‐Cell Analysis

Mingxin Xu, Hui Zhao, Jun Chen, Wenwen Liu, Encheng Li, Qi Wang and Lichuan Zhang

Cytometry Pt A, 2020, 97, 46
DOI: 10.1002/cyto.a.23902

Single-Cell Analysis of Circulating Tumor Cells: How Far Have We Come in the -Omics Era?

Elisabetta Rossi and Rita Zamarchi

Front. Genet., 2019, 10
DOI: 10.3389/fgene.2019.00958

Regulation of actin cytoskeleton via photolithographic micropatterning

Fulin Xing, Haimei Zhang, Mengyu Li, Hao Dong, Xuehe Ma, Shiyu Deng, Fen Hu, Imshik Lee, Leiting Pan and Jingjun Xu

J. Innov. Opt. Health Sci., 2023, 16
DOI: 10.1142/S1793545822440059

See-N-Seq: RNA sequencing of target single cells identified by microscopy via micropatterning of hydrogel porosity

Jeong Hyun Lee, Emily S. Park, Jane Ru Choi, Kerryn Matthews, Alice V. Lam, Xiaoyan Deng, Simon P. Duffy and Hongshen Ma

Commun Biol, 2022, 5
DOI: 10.1038/s42003-022-03703-3

Unravelling tumour heterogeneity by single-cell profiling of circulating tumour cells

Laura Keller and Klaus Pantel

Nat Rev Cancer, 2019, 19, 553
DOI: 10.1038/s41568-019-0180-2

Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications

Payar Radfar, Hamidreza Aboulkheyr Es, Rob Salomon, Arutha Kulasinghe, Naveen Ramalingam, Ehsan Sarafraz-Yazdi, Jean Paul Thiery and Majid Ebrahimi Warkiani

Trends in Biotechnology, 2022, 40, 1041
DOI: 10.1016/j.tibtech.2022.02.004

An Acoustic Droplet-Induced Enzyme Responsive Platform for the Capture and On-Demand Release of Single Circulating Tumor Cells

Xiaoyun Wei, Keke Chen, Bo Cai, Lang Rao, Zixiang Wang, Yue Sun, Mingxia Yu, Wei Liu, Shishang Guo and Xing-Zhong Zhao

ACS Appl. Mater. Interfaces, 2019, 11, 41118
DOI: 10.1021/acsami.9b16566

Mapping cancer biology in space: applications and perspectives on spatial omics for oncology

Sumin Lee, Gyeongjun Kim, JinYoung Lee, Amos C. Lee and Sunghoon Kwon

Mol Cancer, 2024, 23
DOI: 10.1186/s12943-024-01941-z

Circulating tumor cells in bladder cancer: a new horizon of liquid biopsy for precision medicine

Felice Crocetto, Amelia Cimmino, Matteo Ferro and Daniela Terracciano

Journal of Basic and Clinical Physiology and Pharmacology, 2022, 33, 525
DOI: 10.1515/jbcpp-2021-0233

Affinity-Enhanced CTC-Capturing Hydrogel Microparticles Fabricated by Degassed Mold Lithography

Nak Jun Lee, Sejung Maeng, Hyeon Ung Kim, Yoon Ho Roh, Changhyun Hwang, Jongjin Kim, Ki-Tae Hwang and Ki Wan Bong

JCM, 2020, 9, 301
DOI: 10.3390/jcm9020301

Separation and Analysis of Rare Tumor Cells in Various Body Fluids Based on Microfluidic Technology for Clinical Applications

Chang Xu, Dexin Du, Zhaojun Han, Haibin Si, Wei Li, Lu Li and Bo Tang

Anal. Chem., 2025, 97, 7567
DOI: 10.1021/acs.analchem.4c06925

DNA methylome profiling of circulating tumor cells in lung cancer at single base-pair resolution

Lei Zhao, Xiaohong Wu, Junnian Zheng and Dong Dong

Oncogene, 2021, 40, 1884
DOI: 10.1038/s41388-021-01657-0

Current state of cancer immunity cycle: new strategies and challenges of using precision hydrogels to treat breast cancer

Yingze Zhu, Yanlin Su, Yaxin Guo, Xinyue Wang, Zhuoqi Zhang, Yige Lu, Hang Yang and Hui Pang

Front. Immunol., 2025, 16
DOI: 10.3389/fimmu.2025.1535464