Issue 29, 2021

Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

Abstract

β-Lactoglobulin amyloid fibrils are bio-colloids of high interest in many fields (e.g. water purification, cell growth, drug delivery and sensing). While the mechanical properties of pure amyloid fibril gels meet the needs of some applications, mechanical fragility often hinders a wider usage basin. In this work, we present a simple and sustainable approach for reinforcing amyloid fibril hydrogels and aerogels, upon the diffusion of polysaccharides (low-acetylated Gellan Gum and κ-carrageenan) inside their mesh. The formed hybrid materials show enhanced resistance upon compression, without any loss of the exquisite surface reactivity of the amyloid fibrils. The proposed approach can pave the way for designing composite materials that are both highly functional and environmentally friendly.

Graphical abstract: Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

Supplementary files

Article information

Article type
Paper
Submitted
15 Тра 2021
Accepted
25 Чер 2021
First published
25 Чер 2021
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2021,13, 12534-12545

Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

M. Usuelli, T. Germerdonk, Y. Cao, M. Peydayesh, M. Bagnani, S. Handschin, G. Nyström and R. Mezzenga, Nanoscale, 2021, 13, 12534 DOI: 10.1039/D1NR03133C

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