Issue 22, 2017

Multiplexed photoluminescent sensors: towards improved disease diagnostics

Abstract

The ability to simultaneously monitor multiple analytes in, for example, a single microplate well, is important for both basic research and clinical applications. In particular, for disease diagnosis there is a growing awareness that determination of a single disease biomarker is insufficient to pathologically confirm a disease state. Consequently, much recent literature has been directed towards the development of multiplexed photoluminescent sensors which can simultaneously detect multiple and diverse biomarkers that exist in a homogenous solution or a single cell, accelerating the progress towards precise disease diagnosis. This tutorial review highlights a selection of recent contributions towards this emerging interdisciplinary field that incorporates chemistry, chemical biology, materials sciences and medical sciences.

Graphical abstract: Multiplexed photoluminescent sensors: towards improved disease diagnostics

Article information

Article type
Tutorial Review
Submitted
01 Чер 2017
First published
25 Сер 2017
This article is Open Access
Creative Commons BY license

Chem. Soc. Rev., 2017,46, 6687-6696

Multiplexed photoluminescent sensors: towards improved disease diagnostics

X. He, X. Hu, T. D. James, J. Yoon and H. Tian, Chem. Soc. Rev., 2017, 46, 6687 DOI: 10.1039/C6CS00778C

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