Issue 20, 2022

Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring

Abstract

Herein, we report a portable point-of-care testing (POCT) device based on an aptamer-engineered extended-gate field-effect transistor (EG-FET) for therapeutic monitoring of the drug methotrexate. This method was shown to be highly sensitive, efficient, and convenient to use, features contributing to its realizing a clinical detection of drugs in blood.

Graphical abstract: Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring

Supplementary files

Article information

Article type
Communication
Submitted
23 Сер 2022
Accepted
13 Вер 2022
First published
13 Вер 2022

Analyst, 2022,147, 4413-4416

Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring

M. Zhang, J. He, Y. Zheng, G. Shi and M. Zhang, Analyst, 2022, 147, 4413 DOI: 10.1039/D2AN01393B

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