Issue 3, 2015

Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

Abstract

In this article we describe work on the synthesis of bolaphile biomimics composed of glucose head groups and steroidal units linked together by a methylene chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry and thermal polarized light microscopy. The results of these studies show that the thermal stabilities of the lamellar mesophases formed vary linearly as a function of increasing aliphatic composition, which reflects a linear hydrophobic–hydrophilic balance with respect to transition temperatures.

Graphical abstract: Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

Supplementary files

Article information

Article type
Paper
Submitted
15 Жов 2014
Accepted
03 Лис 2014
First published
03 Лис 2014

Org. Biomol. Chem., 2015,13, 783-792

Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation

R. Xu, F. Ali-Rachedi, N. M. Xavier, S. Chambert, F. Ferkous, Y. Queneau, S. J. Cowling, E. J. Davis and J. W. Goodby, Org. Biomol. Chem., 2015, 13, 783 DOI: 10.1039/C4OB02191F

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