Metal-based triazoles as a medical marvel of the modern era: a comprehensive review

Kashif Haseeb, Muhammad Hasnain Mustafa, Wardha Zafar, Abrar Ul Hassan, Zahid Hussain Chohan and Sajjad Hussain Sumrra

RSC Adv., 2026, 16, 1457
DOI: 10.1039/D5RA07766D

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy – a literature review

Hussam Elddin Nabeih Khasawneh, Hesham M. Hassan, Amal Ali Alharbi, Wesam Taher Almagharbeh, Raed Fanoukh Aboqader Al-Aouadi, Kirandeep Kaur, Ramya Maranan, Hadeer M. Farhan, Hamada Hashem, Mariam M. Hassan, Stefan Bräse and Ahmed Al-Emam

RSC Adv., 2025, 15, 40998
DOI: 10.1039/D5RA03819G

Click synthesis of some novel benzo[d]thiazole–1,2,3-triazole hybrid compounds with benzamide and/or benzoate tethers as EGFR-dependent signaling inhibitors against breast cancer

Mosa Alsehli, Mohamed S. Nafie, Nader R. Albujuq, Sanaa Bardaweel, Ateyatallah Aljuhani, Haytham O. Tawfik, Shaya Yahya Alraqa, Mohamed K. Diab, Nadjet Rezki and Mohamed Reda Aouad

RSC Med. Chem., 2025, 16, 5641
DOI: 10.1039/D5MD00662G

Synthetic strategies towards benzothiazole-based compounds of therapeutic potency: experimental, investigational and approved drugs

Reham A. Mohamed-Ezzat and Galal H. Elgemeie

RSC Adv., 2025, 15, 41724
DOI: 10.1039/D5RA03993B

Novel pyridine-1,3,4-oxadiazole linked 1,2,3-triazole hybrids: synthesis, molecular docking, ADME, DFT study and anti-tumor potential

Aezaz Mathakiya, Bonny Patel, Keval Raval, Jignesh H. Kamdar, Smriti Sharma and Jayesh Dhalani

Results in Chemistry, 2025, 16, 102521
DOI: 10.1016/j.rechem.2025.102521

Activity of two-dimensional Cr2CTx MXene for the synthesis of Eugenol-1,2,3-Triazole via click chemistry

Eka Helena Sinaga, Yoga Romdoni, Bayu Ardiansah, Rika Tri Yunarti, Budi Riza Putra, Wulan Tri Wahyuni and Munawar Khalil

Inorganic Chemistry Communications, 2025, 182, 115537
DOI: 10.1016/j.inoche.2025.115537

Mechanochemical Solvent-Free Synthesis and Biological Profiling of Novel 2-Hydrazone-Bridged Benzothiazoles as Potent Anticancer Agents

Ivana Sokol, Hanja Mlinar, Dajana Kučić Grgić, Leentje Persoons, Dirk Daelemans, Moris Mihovilović and Tatjana Gazivoda Kraljević

Sustainable Chemistry, 2025, 6, 41
DOI: 10.3390/suschem6040041

Design, synthesis, and bioevaluation of 1H-1,2,3-triazole-linked quinazolin-4(3H)-one hydroxamic acids as novel histone deacetylase inhibitors

Nguyen Phuong Dung, Hwa Kyung Kim, Vo Thi Minh Huyen, Da Hyeon Kang, Ha Young Kim, Jong Soon Kang, Duong Tien Anh, Truong Thanh Tung, Sang-Bae Han and Nguyen-Hai Nam

Journal of Molecular Structure, 2026, 1349, 143653
DOI: 10.1016/j.molstruc.2025.143653

Structural, supramolecular analysis, and photoluminescence properties of a new hydroxybenzohydrazide Schiff base

David Oliveros Garavito, Andrea Pastrana-Dávila, Javier Ellena, Pedro H.O. Santiago, Oscar Rojas, Dominik Pentlehner, Luis A. Illicachi and Richard D’Vries

Journal of Molecular Structure, 2026, 1357, 145191
DOI: 10.1016/j.molstruc.2025.145191

Novel Triazole-Carbohydrazide hydrazones with dual antioxidant and antibacterial potential

Safa A. Badawy, Nagwan M. Rewish, Ahmed A. Fadda and Mohamed R. Elmorsy

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-26016-x

Molecular and crystal engineering of a semicarbazide–ketone condensate: A multitechnique characterization

Fatou Dieng, Papa Aly Gueye, Mouhamadou Birame Diop, Adrienne Ndiolene, Mouhamadou Sembene Boye, Shova Sergiu and Aminata Diassé-Sarr

EJCS, 2025, 379
DOI: 10.34198/ejcs.12425.379396

Chemical induction of ferroptosis through GPX4 inhibition: Rational design of triazole-benzoxazine hybrids for melanoma therapy

Bingbing Feng, Yuxin Chen, Haizhou Fu, Yufei Li, Jingjing Guo, Xixi Hou, Huibin Xu and Shuxiang Xu

European Journal of Medicinal Chemistry, 2026, 303, 118434
DOI: 10.1016/j.ejmech.2025.118434

Design, synthesis, biological evaluation, and computational studies of triazole-containing Schiff base compounds

Büşra Albayrak Misir, Jülide Nacaroğlu Balli, Ramazan Korkmaz, İbrahim Seyfettin Çelik, Muhammad Sirajuddin, Muhammad Sadeeq and Muhammet Köse

Journal of Molecular Liquids, 2026, 452, 129492
DOI: 10.1016/j.molliq.2026.129492

Catalyst‐Free Mannich Approach to 1‐(Benzothiazolylamino)Methyl‐2‐Naphthols: Synthesis, NMR Insights, and Molecular Docking Studies

Roshmi Devi, Pabitra Kumar Kalita, Bikash Baishya, Samiyara Begum, Paramartha Gogoi, Mrityunjoy Dey and Mohit L. Deb

ChemistrySelect, 2026, 11
DOI: 10.1002/slct.73041

Recent Developments in Pharmacological Outcomes of Synthetic Triazoles: A Comprehensive Review

Divyakshi Arya, Farmeena Shafaq, Shweta Singh, Gulshan Aara Khan, Anjali Upadhyay, M. L. Sharma, Som Shankar Dubey, Hema Bisht, Vishnu Prabhakar Srivastava, Prateek Pathak, Ashish Ranjan Dwivedi and Sarvesh Kumar Pandey

Archiv der Pharmazie, 2025, 358
DOI: 10.1002/ardp.70103

Advances in click chemistry for drug discovery and development

Jiaojiao Dai, Xiaojia Xue, Xiangyi Jiang, Xinyong Liu and Peng Zhan

Expert Opinion on Drug Discovery, 2025, 20, 1327
DOI: 10.1080/17460441.2025.2552146

Benzothiazole-Based Therapeutics: FDA Insights and Clinical Advances

Subba Rao Cheekatla

Chemistry, 2025, 7, 118
DOI: 10.3390/chemistry7040118