Laura Powell, Rodrigo Sergio Wiederkehr, Paige Damascus, Maarten Fauvart, Federico Buja, Tim Stakenborg, Stuart C. Ray, Paolo Fiorini and William O. Osburn

Analyst, 2018, 143, 2596
DOI: 10.1039/C8AN00552D

Controlled droplet discretization and manipulation using membrane displacement traps

S. Padmanabhan, T. Misteli and D. L. DeVoe

Lab Chip, 2017, 17, 3717
DOI: 10.1039/C7LC00910K

Microfluidic exponential rolling circle amplification for sensitive microRNA detection directly from biological samples

Hongmei Cao, Xin Zhou and Yong Zeng

Sensors and Actuators B: Chemical, 2019, 279, 447
DOI: 10.1016/j.snb.2018.09.121

Biomolecular Monitoring Tool Based on Lab-on-Chip for Virus Detection

Francesca Costantini, Nicola Lovecchio, Manasa Nandimandalam, Ariana Manglli, Francesco Faggioli, Mara Biasin, Cesare Manetti, Pio Federico Roversi, Augusto Nascetti, Giampiero de Cesare and Domenico Caputo

Biosensors, 2023, 13, 544
DOI: 10.3390/bios13050544

The evolution of analytical techniques for multiplex analysis of protein biomarkers

Hyeyoon Kim, David Ross Hall, Lorenz Nierves, Tai-Tu Lin, Reta Birhanu Kitata, Tujin Shi and Tao Liu

Expert Review of Proteomics, 2025, 22, 255
DOI: 10.1080/14789450.2025.2529185

Evaluation of a microfluidic-based point-of-care prototype with customized chip for detection of bacterial clusters

Janina Treffon, Nicole Isserstedt-John, Richard Klemm, Claudia Gärtner, Alexander Mellmann and Sen Pei

Microbiol Spectr, 2024, 12
DOI: 10.1128/spectrum.00862-24

Overcoming bubble formation in polydimethylsiloxane-made PCR chips: mechanism and elimination with a high-pressure liquid seal

Shiyuan Gao, Tiegang Xu, Lei Wu, Xiaoyue Zhu, Xuefeng Wang, Xiaohong Jian and Xinxin Li

Microsyst Nanoeng, 2024, 10
DOI: 10.1038/s41378-024-00725-1

A pocket-sized device automates multiplexed point-of-care RNA testing for rapid screening of infectious pathogens

Bowen Shu, Ling Lin, Bin Wu, Enqi Huang, Yu Wang, Zhujun Li, Haoyan He, Xiuxia Lei, Banglao Xu and Dayu Liu

Biosensors and Bioelectronics, 2021, 181, 113145
DOI: 10.1016/j.bios.2021.113145

A capillary-driven microfluidic device for performing spatial multiplex PCR

Rodrigo S. Wiederkehr, Elisabeth Marchal, Maarten Fauvart, Tomas Forceville, Ahmed Taher, Tim Steylaerts, YoungJae Choe, Hans Dusar, Silvia Lenci, Eleni Siouti, Vassiliki T. Potsika, Evangelos Andreakos and Tim Stakenborg

Biomed Microdevices, 2025, 27
DOI: 10.1007/s10544-025-00745-2

Microchip Devices for Nucleic Acid Amplification

Ya. S. Posmitnaya, A. L. Bulyanitsa, A. N. Tupik, G. E. Rudnitskaya, N. A. Esikova, T. A. Lukashenko, A. I. Tsymbalov and A. A. Evstrapov

Tech. Phys., 2018, 63, 1361
DOI: 10.1134/S1063784218090165

Unlocking the potential of microfluidics in mass spectrometry-based immunopeptidomics for tumor antigen discovery

Charlotte Stutzmann, Jiaxi Peng, Zhaoguan Wu, Christopher Savoie, Isabelle Sirois, Pierre Thibault, Aaron R. Wheeler and Etienne Caron

Cell Reports Methods, 2023, 3, 100511
DOI: 10.1016/j.crmeth.2023.100511

Flow characteristics at the interface during droplet formation in a flow-focusing microfluidic channel—numerical analysis of dripping and jetting regimes

Emil Grigorov, Jordan A. Denev, Boris Kirov and Vassil Galabov

Acta Mech, 2024, 235, 6057
DOI: 10.1007/s00707-024-04031-9

Fused Deposition Modeling of Microfluidic Chips in Transparent Polystyrene

Markus Mader, Christof Rein, Eveline Konrat, Sophia Lena Meermeyer, Cornelia Lee-Thedieck, Frederik Kotz-Helmer and Bastian E. Rapp

Micromachines, 2021, 12, 1348
DOI: 10.3390/mi12111348

A point of care platform based on microfluidic chip for nucleic acid extraction in less than 1 minute

Jianzhong Zhang, Xiaosong Su, Jiasu Xu, Jin Wang, Juntian Zeng, Caiyu Li, Wendi Chen, Tingdong Li, Xiaoping Min, Dongxu Zhang, Shiyin Zhang, Shengxiang Ge, Jun Zhang and Ningshao Xia

Biomicrofluidics, 2019, 13
DOI: 10.1063/1.5088552

Micro-polymerase chain reaction for point-of-care detection and beyond: a review microfluidics and nanofluidics

Gamze Tilbe İnce, Mehmet Yüksekkaya and Orhan Erdem Haberal

Microfluid Nanofluid, 2023, 27
DOI: 10.1007/s10404-023-02677-w

Advances in continuous-flow based microfluidic PCR devices—a review

Madhusudan B Kulkarni and Sanket Goel

Eng. Res. Express, 2020, 2, 042001
DOI: 10.1088/2631-8695/abd287

Nucleic Acids Analysis

Yongxi Zhao, Xiaolei Zuo, Qian Li, Feng Chen, Yan-Ru Chen, Jinqi Deng, Da Han, Changlong Hao, Fujian Huang, Yanyi Huang, Guoliang Ke, Hua Kuang, Fan Li, Jiang Li, Min Li, Na Li, Zhenyu Lin, Dingbin Liu, Juewen Liu, Libing Liu, Xiaoguo Liu, Chunhua Lu, Fang Luo, Xiuhai Mao, Jiashu Sun, Bo Tang, Fei Wang, Jianbin Wang, Lihua Wang, Shu Wang, Lingling Wu, Zai-Sheng Wu, Fan Xia, Chuanlai Xu, Yang Yang, Bi-Feng Yuan, Quan Yuan, Chao Zhang, Zhi Zhu, Chaoyong Yang, Xiao-Bing Zhang, Huanghao Yang, Weihong Tan and Chunhai Fan

Sci. China Chem., 2021, 64, 171
DOI: 10.1007/s11426-020-9864-7

A roadmap to high-speed polymerase chain reaction (PCR): COVID-19 as a technology accelerator

Masoud Madadelahi, Rahul Agarwal, Sergio O. Martinez-Chapa and Marc J. Madou

Biosensors and Bioelectronics, 2024, 246, 115830
DOI: 10.1016/j.bios.2023.115830

Portable, Automated and Deep‐Learning‐Enabled Microscopy for Smartphone‐Tethered Optical Platform Towards Remote Homecare Diagnostics: A Review

Kisoo Kim and Won Gu Lee

Small Methods, 2023, 7
DOI: 10.1002/smtd.202200979

Rapid Microfluidic Mixing Method Based on Droplet Rotation Due to PDMS Deformation

Chunyang Wei, Chengzhuang Yu, Shanshan Li, Feng Pan, Tiejun Li, Zichao Wang and Junwei Li

Micromachines, 2021, 12, 901
DOI: 10.3390/mi12080901

All-in-One Digital Microfluidics System for Molecular Diagnosis with Loop-Mediated Isothermal Amplification

Siyi Hu, Yuhan Jie, Kai Jin, Yifan Zhang, Tianjie Guo, Qi Huang, Qian Mei, Fuqiang Ma and Hanbin Ma

Biosensors, 2022, 12, 324
DOI: 10.3390/bios12050324

Rapid Multiplex RT-PCR for Influenza A and B by Genesoc^®, a Microfluidic PCR System

Miyako Takata, Masaki Nakamoto, Tsuyoshi Kitaura, Kensaku Okada, Akeno Tsuneki-tokunaga, Akira Yamasaki, Seiji Kageyama, Naoto Burioka and Hiroki Chikumi

Yonago Acta Med., 2023, 66, 223
DOI: 10.33160/yam.2023.05.007

Fluidic handling system for PCR-based sample-to-answer detection of viral nucleic acids

Islam Seder, Dong-Min Kim, Sang-Hyun Hwang, Heungsup Sung, Dong-Eun Kim and Sung-Jin Kim

Sensors and Actuators B: Chemical, 2021, 349, 130788
DOI: 10.1016/j.snb.2021.130788

Hairpin allosteric molecular beacons-based cascaded amplification for effective detection of lung cancer-associated microRNA

Cheng Zheng, Xuemei Hu, Shujuan Sun, Lingye Zhu, Ning Wang, Jing Zhang, Guoqiao Huang, Yuzhe Wang, Xiaoying Huang, Liangxing Wang and Zhifa Shen

Talanta, 2022, 244, 123412
DOI: 10.1016/j.talanta.2022.123412

Ultra-fast PCR technologies for point-of-care testing

Lars Ullerich, Stephanie Campbell, Frank Krieg-Schneider, Federico Bürsgens and Joachim Stehr

LaboratoriumsMedizin, 2017, 41, 239
DOI: 10.1515/labmed-2017-0093

Fabrication routes via projection stereolithography for 3D-printing of microfluidic geometries for nucleic acid amplification

Charalampos Tzivelekis, Pavlos Sgardelis, Kevin Waldron, Richard Whalley, Dehong Huo, Kenny Dalgarno and Andreas Offenhausser

PLoS ONE, 2020, 15, e0240237
DOI: 10.1371/journal.pone.0240237

Integrated Electrochemical Biosensors for Detection of Waterborne Pathogens in Low-Resource Settings

Joshua Rainbow, Eliska Sedlackova, Shu Jiang, Grace Maxted, Despina Moschou, Lukas Richtera and Pedro Estrela

Biosensors, 2020, 10, 36
DOI: 10.3390/bios10040036

Applications of microfluidics in biosensing

Masindi Sekhwama, Kelvin Mpofu, Sudesh Sivarasu and Patience Mthunzi-Kufa

Discov Appl Sci, 2024, 6
DOI: 10.1007/s42452-024-05981-4

Proposal of a Rapid Detection System Using Image Analysis for ELISA with an Autonomous Centrifugal Microfluidic System

Shunya Okamoto, Yuto Mori, Shota Nakamura, Yusuke Kanai, Yoshiaki Ukita, Moeto Nagai and Takayuki Shibata

Micromachines, 2024, 15, 1387
DOI: 10.3390/mi15111387

Ultrafast Photonic PCR Based on Photothermal Nanomaterials

Minli You, Zedong Li, Shangsheng Feng, Bin Gao, Chunyan Yao, Jie Hu and Feng Xu

Trends in Biotechnology, 2020, 38, 637
DOI: 10.1016/j.tibtech.2019.12.006

Advancement in the Synthesis and Nanocomposite Formation of Upconversion Nanomaterials in the Fluorescence Detection of Food Contaminants

Daohong Zhang, Deepak Kukkar, Ki-Hyun Kim and Monika Chhillar

Food Bioprocess Technol, 2025, 18, 4923
DOI: 10.1007/s11947-025-03760-6

Design and fabrication of a two-phase diamond nanoparticle aided fast PCR device

Masoud Madadelahi, Erfan Ghazimirsaeed and Amir Shamloo

Analytica Chimica Acta, 2019, 1068, 28
DOI: 10.1016/j.aca.2019.02.050

High-thermal-conductivity integrated EWOD chip for ultra-fast, low-cost pathogen detection

Fangzhou Zhang, Kun Wang, Xiaoqiang Shu, Danfeng Su, Yongjie Yu, Chang Chen, Jianlong Zhao, Shilun Feng and Bo Liu

Analytica Chimica Acta, 2026, 1398, 345227
DOI: 10.1016/j.aca.2026.345227

A sample-to-answer labdisc platform integrated novel membrane-resistance valves for detection of highly pathogenic avian influenza viruses

Qi Liu, Xinlian Zhang, Liping Chen, Yuhan Yao, Shaorui Ke, Wang Zhao, Zifeng Yang and Guodong Sui

Sensors and Actuators B: Chemical, 2018, 270, 371
DOI: 10.1016/j.snb.2018.05.044

A Poisson-Independent Approach to Precision Nucleic Acid Quantification in Microdroplets

Reya Ganguly and Chang-Soo Lee

ACS Appl. Bio Mater., 2024, 7, 3441
DOI: 10.1021/acsabm.4c00350

Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

Prapti Pattanayak, Sachin Kumar Singh, Monica Gulati, Sukriti Vishwas, Bhupinder Kapoor, Dinesh Kumar Chellappan, Krishnan Anand, Gaurav Gupta, Niraj Kumar Jha, Piyush Kumar Gupta, Parteek Prasher, Kamal Dua, Harish Dureja, Deepak Kumar and Vijay Kumar

Microfluid Nanofluid, 2021, 25
DOI: 10.1007/s10404-021-02502-2

Peanut Detection Using Droplet Microfluidic Polymerase Chain Reaction Device

Shou-Yu Ma, Yu-Cheng Chiang, Chia-Hsien Hsu, Jyh-Jian Chen, Chin-Chi Hsu, An-Chong Chao and Yung-Sheng Lin

Journal of Sensors, 2019, 2019, 1
DOI: 10.1155/2019/4712084

Origin of Species before Origin of Life: The Role of Speciation in Chemical Evolution

Tony Z. Jia, Melina Caudan and Irena Mamajanov

Life, 2021, 11, 154
DOI: 10.3390/life11020154

A fully integrated microdevice for capturing, amplification, and colorimetric detection of foodborne pathogens

Hoang Chau La and Nae Yoon Lee

Microsyst Technol, 2020, 26, 3875
DOI: 10.1007/s00542-020-04877-8

Extreme PCR Meets High-Speed Melting: A Step Closer to Molecular Diagnostics “While You Wait”

G Mike Makrigiorgos

Clinical Chemistry, 2019, 65, 217
DOI: 10.1373/clinchem.2018.298356

Green chemistry and coronavirus

Sepideh Ahmadi, Navid Rabiee, Yousef Fatahi, Seyyed Emad Hooshmand, Mojtaba Bagherzadeh, Mohammad Rabiee, Vahid Jajarmi, Rassoul Dinarvand, Sajjad Habibzadeh, Mohammad Reza Saeb, Rajender S. Varma, Mohammadreza Shokouhimehr and Michael R. Hamblin

Sustainable Chemistry and Pharmacy, 2021, 21, 100415
DOI: 10.1016/j.scp.2021.100415

Development and validation of a DNA‐based multi‐species biomonitoring toolkit using a high‐throughput qPCR platform: A case study of Irish shellfish species

Dennis van der Pouw Kraan, Conor T. Graham, Fiona Kavanagh and Luca Mirimin

Molecular Ecology Resources, 2024, 24
DOI: 10.1111/1755-0998.13945

A plasmonic gold nanofilm-based microfluidic chip for rapid and inexpensive droplet-based photonic PCR

Abbas Jalili, Maryam Bagheri, Amir Shamloo and Amir Hossein Kazemipour Ashkezari

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-02535-1

Chip‐based duplex real‐time PCR for water quality monitoring concerning Legionella pneumophila and Legionella spp.

Cornelia Reuter, Stefanie Hentschel, Antje Breitenstein, Eileen Heinrich, Oliver Aehlig, Thomas Henkel, Andrea Csáki and Wolfgang Fritzsche

Water & Environment J, 2021, 35, 371
DOI: 10.1111/wej.12635

Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis

Samuel C. Kim, Iain C. Clark, Payam Shahi and Adam R. Abate

Anal. Chem., 2018, 90, 1273
DOI: 10.1021/acs.analchem.7b04050

Enhanced sample filling and discretization in thermoplastic 2D microwell arrays using asymmetric contact angles

S. Padmanabhan, J. Y. Han, I. Nanayankkara, K. Tran, P. Ho, N. Mesfin, I. White and D. L. DeVoe

Biomicrofluidics, 2020, 14
DOI: 10.1063/1.5126938

A developed cascade DNA recycling amplification integrating with microchip electrophoresis for ultrasensitive detection of Cronobacter sakazakii

Shuang Tang, Xing Geng, Jianan Lv, Mengmeng Han, Sijin Li, Fan Zhang and Qingjiang Wang

Analytica Chimica Acta, 2026, 1404, 345453
DOI: 10.1016/j.aca.2026.345453

Ultrafast and real-time on-chip quantitative polymerase chain reaction (ROC-qPCR) with sequence-specific signaling

Hyun Shin and Cheulhee Jung

Analytica Chimica Acta, 2026, 1402, 345409
DOI: 10.1016/j.aca.2026.345409

Rapid detection of antibiotic resistance genes in lactic acid bacteria using PMMA-based microreactor arrays

Zengjun Jin, Guotao Ding, Guoxing Yang, Guiying Li, Wei Zhang, Lixin Yang and Weihao Li

Appl Microbiol Biotechnol, 2020, 104, 6375
DOI: 10.1007/s00253-020-10699-5

Portable hepatitis C virus RNA extraction and stabilization using low-cost lab-on-a-chip style components with shelf stable reagents

Sarah Hernandez, Dhruv Miglani, Jayden Kimbro, Alessandra Luna, Heather Jones, Benjamin A. Pinsky, Jesse J. Waggoner and David R. Myers

Sensors and Actuators B: Chemical, 2025, 437, 137712
DOI: 10.1016/j.snb.2025.137712

Rubik’s Cube as Reconfigurable Microfluidic Platform for Rapid Setup and Switching of Analytical Devices

Xiaochen Lai, Yanfei Sun, Mingpeng Yang and Hao Wu

Micromachines, 2022, 13, 2054
DOI: 10.3390/mi13122054

Modeling of PCR: Kinetic Explanation for Short‐Chained Side Products

Christian D. Ahrberg

Chemie Ingenieur Technik, 2018, 90, 1047
DOI: 10.1002/cite.201700132

Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation

Xiangke Li, Shi‐Yang Tang, Yang Zhang, Jiayuan Zhu, Helen Forgham, Chun‐Xia Zhao, Cheng Zhang, Thomas P. Davis and Ruirui Qiao

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202315552

3D Printed Microfluidic Devices for Solid-Phase Extraction and On-Chip Fluorescent Labeling of Preterm Birth Risk Biomarkers

Anna V. Bickham, Chao Pang, Benjamin Q. George, David J. Topham, Jacob B. Nielsen, Gregory P. Nordin and Adam T. Woolley

Anal. Chem., 2020, 92, 12322
DOI: 10.1021/acs.analchem.0c01970

A microheater on polyimide substrate for hand-held realtime microfluidic polymerase chain reaction amplification

Dae-Sik Lee, Ok Ran Choi and Yujin Seo

Micro and Nano Syst Lett, 2019, 7
DOI: 10.1186/s40486-019-0098-1

Nanoplasmonic On-Chip PCR for Rapid Precision Molecular Diagnostics

Youngseop Lee, Byoung-Hoon Kang, Minhee Kang, Doo Ryeon Chung, Gwan-Su Yi, Luke P. Lee and Ki-Hun Jeong

ACS Appl. Mater. Interfaces, 2020, 12, 12533
DOI: 10.1021/acsami.9b23591

Rapid PCR powered by microfluidics: A quick review under the background of COVID-19 pandemic

Xiaobin Dong, Luyao Liu, Yunping Tu, Jing Zhang, Guijun Miao, Lulu Zhang, Shengxiang Ge, Ningshao Xia, Duli Yu and Xianbo Qiu

TrAC Trends in Analytical Chemistry, 2021, 143, 116377
DOI: 10.1016/j.trac.2021.116377

Integrated Extreme Real-Time PCR and High-Speed Melting Analysis in 52 to 87 Seconds

Joseph T Myrick, Robert J Pryor, Robert A Palais, Sean J Ison, Lindsay Sanford, Zachary L Dwight, Jarkko J Huuskonen, Scott O Sundberg and Carl T Wittwer

Clinical Chemistry, 2019, 65, 263
DOI: 10.1373/clinchem.2018.296608

Temperature Control in Microfluidic Devices: Approaches, Challenges, and Future Directions

Faisal bin Nasser Sarbaland, Masashi Kobayashi, Daiki Tanaka, Risa Fujita, Nobuyuki Tanaka and Masahiro Furuya

Applied Sciences, 2025, 15, 9902
DOI: 10.3390/app15189902

Towards on-site detection of gluten-containing cereals with a portable and miniaturized prototype combining isothermal DNA amplification and naked eye detection

Joana Carvalho, Andrey Ipatov, Laura Rodriguez-Lorenzo, Alejandro Garrido-Maestu, Sarah Azinheiro, Begoña Espiña, Jorge Barros-Velázquez and Marta Prado

Microchemical Journal, 2022, 183, 108115
DOI: 10.1016/j.microc.2022.108115

Accomplishment of one-step specific PCR and evaluated SELEX process by a dual-microfluidic amplified system

Jing Chen, Xiaohui Liu, Meng Xu, Zhoumin Li and Danke Xu

Biomicrofluidics, 2021, 15
DOI: 10.1063/5.0045965

The Potential Clinical Applications of a Microfluidic Lab-on-a-Chip for the Identification and Antibiotic Susceptibility Testing of Enterococcus faecalis-Associated Endodontic Infections: A Systematic Review

Carlos M. Ardila, Gustavo A. Jiménez-Arbeláez and Annie Marcela Vivares-Builes

Dentistry Journal, 2023, 12, 5
DOI: 10.3390/dj12010005

Microfluidic assessment of nutritional biomarkers: Concepts, approaches and advances

Shubham Nimbkar, M. Maria Leena, Jeyan Arthur Moses and Chinnaswamy Anandharamakrishnan

Critical Reviews in Food Science and Nutrition, 2024, 64, 5113
DOI: 10.1080/10408398.2022.2150597

Self-assembled sensor-in-a-tube as a versatile tool for label-free EIS viability investigation of cervical cancer cells

Eashika Ghosh, Aleksandr I. Egunov, Daniil Karnaushenko, Mariana Medina-Sánchez and Oliver G. Schmidt

Frequenz, 2022, 76, 729
DOI: 10.1515/freq-2022-0090

Advancing DNA-based quantification of Pacific oyster larvae using a HTqPCR multi-marker approach

Dennis van der Pouw Kraan, Conor T. Graham, Fiona Kavanagh and Luca Mirimin

Journal of Experimental Marine Biology and Ecology, 2024, 581, 152055
DOI: 10.1016/j.jembe.2024.152055

Ecotoxicology Goes on a Chip: Embracing Miniaturized Bioanalysis in Aquatic Risk Assessment

Olivia Campana and Donald Wlodkowic

Environ. Sci. Technol., 2018, 52, 932
DOI: 10.1021/acs.est.7b03370

Innovative approaches for microfluidics techniques in tissue engineering and revolutionizing sports medicine: Enhancing athletic performance and recovery using finite element and statistical analysis

Yu Ruida, Rong Siyu, Qi Yufei, A. Shahbaz and Sh. Baghaei

Tissue and Cell, 2026, 99, 103251
DOI: 10.1016/j.tice.2025.103251

Digital Microfluidics for Nucleic Acid Amplification

Beatriz Coelho, Bruno Veigas, Elvira Fortunato, Rodrigo Martins, Hugo Águas, Rui Igreja and Pedro Baptista

Sensors, 2017, 17, 1495
DOI: 10.3390/s17071495

Droplet-based lab-on-chip platform integrated with laser ablated graphene heaters to synthesize gold nanoparticles for electrochemical sensing and fuel cell applications

Sangam Srikanth, Sohan Dudala, U. S. Jayapiriya, J. Murali Mohan, Sushil Raut, Satish Kumar Dubey, Idaku Ishii, Arshad Javed and Sanket Goel

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-88068-z

A novel recyclable surface-enhanced Raman spectroscopy platform with duplex-specific nuclease signal amplification for ultrasensitive analysis of microRNA 155

Yige Wu, Yi He, Xia Yang, Ruo Yuan and Yaqin Chai

Sensors and Actuators B: Chemical, 2018, 275, 260
DOI: 10.1016/j.snb.2018.08.057

Simulation and Optimization of a Single Heater Convective PCR Chip and Its Controller for Fast Salmonella Enteritidis Detection

Ruba Khnouf, Mohammad Abdel Kareem Jaradat, Dina Karasneh, Farah Al-Shami, Laith Sawaqed and Borhan Aldeen Albiss

IEEE Sensors J., 2020, 20, 13186
DOI: 10.1109/JSEN.2020.3004285

Virtual Multiplexing Chamber-Based Digital PCR for Camel Milk Authentication Applications

Jinchao Li, Jingmeng Cheng, Shanshan Li, Jie Jayne Wu and Junwei Li

Micromachines, 2023, 14, 1619
DOI: 10.3390/mi14081619

Numerical Simulation and Experimental Verification of Droplet Generation in Microfluidic Digital PCR Chip

Xiangkai Meng, Yuanhua Yu and Guangyong Jin

Micromachines, 2021, 12, 409
DOI: 10.3390/mi12040409

Heat Transfer and Flow Characteristics of Coal Slurries under the Temperature Difference between Inside and Outside of the Channel

Yang Liu, Xintao Hu, Feng Gao and Yanan Gao

Applied Sciences, 2022, 12, 12028
DOI: 10.3390/app122312028

Polymer-based microfluidic chips for isothermal amplification of nucleic acids

Y S Posmitnaya, G E Rudnitskaya, A N Tupik, T A Lukashenko, A C Bukatin and A A Evstrapov

J. Phys.: Conf. Ser., 2017, 917, 042012
DOI: 10.1088/1742-6596/917/4/042012

Blocked recombinase polymerase amplification for mutation analysis of PIK3CA gene

Sara Martorell, Sarai Palanca, Ángel Maquieira and Luis A. Tortajada-Genaro

Analytical Biochemistry, 2018, 544, 49
DOI: 10.1016/j.ab.2017.12.013

Sample‐to‐answer salivary miRNA testing: New frontiers in point‐of‐care diagnostic technologies

Zhikun Zhang, Tianyi Liu, Ming Dong, Md. Ahasan Ahamed and Weihua Guan

WIREs Nanomed Nanobiotechnol, 2024, 16
DOI: 10.1002/wnan.1969

Thermal gradient for fluorometric optimization of droplet PCR in virtual reaction chambers

Xiangping Li, Wenming Wu and Andreas Manz

Microchim Acta, 2017, 184, 3433
DOI: 10.1007/s00604-017-2353-6

Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus

L. A. Shkodenko, V. O. Laushkina, M. S. Rubel and E. Sergeeva

Russ J Bioorg Chem, 2024, 50, 544
DOI: 10.1134/S106816202411044X

Modular micro-PCR system for the onsite rapid diagnosis of COVID-19

Phuong Quoc Mai Nguyen, Ming Wang, Nelisha Ann Maria, Adelicia Yongling Li, Hsih Yin Tan, Gordon Minru Xiong, Meng-Kwang Marcus Tan, Ali Asgar S. Bhagat, Catherine W. M. Ong and Chwee Teck Lim

Microsyst Nanoeng, 2022, 8
DOI: 10.1038/s41378-022-00400-3

Biomimetic micropump: Leveraging a novel propagative rhythmic membrane function

Mahesh Kumar, Jaikishan Mansukhani, Arijeet Tripathy and Pranab Kumar Mondal

Physics of Fluids, 2023, 35
DOI: 10.1063/5.0144986

Microfluidic detection of human diseases: From liquid biopsy to COVID-19 diagnosis

Kuan Jiang, Doorgesh Sharma Jokhun and Chwee Teck Lim

Journal of Biomechanics, 2021, 117, 110235
DOI: 10.1016/j.jbiomech.2021.110235

From droplets to diagnosis: AI-driven imaging and system integration in digital nucleic acid amplification testing

Yuanyuan Wei, Xianxian Liu, Yao Mu, Changran Xu, Guoxun Zhang, Tianhao Li, Zida Li, Wu Yuan, Ho-Pui Ho and Mingkun Xu

Biosensors and Bioelectronics, 2025, 288, 117741
DOI: 10.1016/j.bios.2025.117741

Genome Target Evaluator (GTEvaluator): A workflow exploiting genome dataset to measure the sensitivity and specificity of genetic markers

Arnaud Felten, Laurent Guillier, Nicolas Radomski, Michel-Yves Mistou, Renaud Lailler, Sabrina Cadel-Six and Muna Anjum

PLoS ONE, 2017, 12, e0182082
DOI: 10.1371/journal.pone.0182082

Asymmetric fluttering ferromagnetic bar-driven inertial micropump in microfluidics

Wonwhi Na, Jinsung Kim, Hoyoon Lee, Byeongmin Yoo and Sehyun Shin

Biomicrofluidics, 2018, 12
DOI: 10.1063/1.5017902

Fully integrated microfluidic devices for qualitative, quantitative and digital nucleic acids testing at point of care

Zedong Li, Yuemeng Bai, Minli You, Jie Hu, Chunyan Yao, Lei Cao and Feng Xu

Biosensors and Bioelectronics, 2021, 177, 112952
DOI: 10.1016/j.bios.2020.112952

Biochip for Real-Time Monitoring of Hepatitis B Virus (HBV) by Combined Loop-Mediated Isothermal Amplification and Solution-Phase Electrochemical Detection

Bui Quang Tien, Nguyen Thy Ngoc, Nguyen Thai Loc, Vu Thi Thu and Tran Dai Lam

Journal of Elec Materi, 2017, 46, 3565
DOI: 10.1007/s11664-017-5483-z

Investigation and Modeling of the Magnetic Nanoparticle Aggregation with a Two-Phase CFD Model

Péter Pálovics, Márton Németh and Márta Rencz

Energies, 2020, 13, 4871
DOI: 10.3390/en13184871

Ultrafast Real-Time PCR in Photothermal Microparticles

Bong Kyun Kim, Sang-A Lee, Minju Park, Eui Ju Jeon, Mi Jung Kim, Jung Min Kim, Heesuk Kim, Seungwon Jung and Sang Kyung Kim

ACS Nano, 2022, 16, 20533
DOI: 10.1021/acsnano.2c07017

Application of Microfluidics for Bacterial Identification

Fraser Daniel, Delaney Kesterson, Kevin Lei, Catherine Hord, Aarti Patel, Anastasia Kaffenes, Harrshavasan Congivaram and Shaurya Prakash

Pharmaceuticals, 2022, 15, 1531
DOI: 10.3390/ph15121531

On the Application of Microfluidic-Based Technologies in Forensics: A Review

Hanieh Bazyar

Sensors, 2023, 23, 5856
DOI: 10.3390/s23135856

Complex Nucleic Acid Hybridization Reactions inside Capillary‐Driven Microfluidic Chips

Marie L. Salva, Marco Rocca, Yong Hu, Emmanuel Delamarche and Christof M. Niemeyer

Small, 2020, 16
DOI: 10.1002/smll.202005476

Taking the microfluidic approach to nucleic acid analysis in forensics: Review and perspectives

Rachelle Turiello, Renna L. Nouwairi and James P. Landers

Forensic Science International: Genetics, 2023, 63, 102824
DOI: 10.1016/j.fsigen.2022.102824

LAMP-on-a-chip: Revising microfluidic platforms for loop-mediated DNA amplification

Haoqing Zhang, Ying Xu, Zdenka Fohlerova, Honglong Chang, Ciprian Iliescu and Pavel Neuzil

TrAC Trends in Analytical Chemistry, 2019, 113, 44
DOI: 10.1016/j.trac.2019.01.015

Localized air-mediated heating method for isothermal and rapid thermal processing on lab-on-a-disk platforms

Esmail Pishbin, Manouchehr Eghbal, Mahdi Navidbakhsh and Mohammad Zandi

Sensors and Actuators B: Chemical, 2019, 294, 270
DOI: 10.1016/j.snb.2019.05.039

Based on intervening PCR for detection of alkaline phosphatase and zearalenone

Liyuan Ma, Xingping Zhang, Yu Peng, Wang Chen, Yao Xiao, Huajuan Fang, Hualin Yang and Yu Zhou

Microchemical Journal, 2023, 186, 108314
DOI: 10.1016/j.microc.2022.108314

Surface roughness impact on bioinspired rhythmic contractile microfluidic membrane pumping mechanism: A computational analysis

Hanumesh Vaidya, K. V. Prasad, Rajashekhar V. Choudhari, Dharmendra Tripathi and Mahalingappa Naganur

Physics of Fluids, 2025, 37
DOI: 10.1063/5.0261414

A Glass–Ultra-Thin PDMS Film–Glass Microfluidic Device for Digital PCR Application Based on Flexible Mold Peel-Off Process

Yanming Xia, Xianglong Chu, Caiming Zhao, Nanxin Wang, Juan Yu, Yufeng Jin, Lijun Sun and Shenglin Ma

Micromachines, 2022, 13, 1667
DOI: 10.3390/mi13101667

A multi-channel polymerase chain reaction lab-on-a-chip and its application in spaceflight experiment for the study of gene mutation

Chunhua Yang, Yulin Deng, Hao Ren, Rui Wang and Xiaoqiong Li

Acta Astronautica, 2020, 166, 590
DOI: 10.1016/j.actaastro.2018.11.049

Separation, Purification, and Detection of cfDNA in a Microfluidic Device

Hyeon Gi Kye, Christian D. Ahrberg, Byeong Seon Park, Jong Min Lee and Bong Geun Chung

BioChip J, 2020, 14, 195
DOI: 10.1007/s13206-020-4208-1

Analysis of augmented droplet transport during electrowetting over triangular coplanar electrode array

Mainak Basu, Vedant P. Joshi, Soumen Das and Sunando DasGupta

Journal of Electrostatics, 2021, 109, 103541
DOI: 10.1016/j.elstat.2020.103541

Fast Thermocycling in Custom Microfluidic Cartridge for Rapid Single-Molecule Droplet PCR

Hirokazu Takahara, Hayato Tanaka and Masahiko Hashimoto

Sensors, 2023, 23, 9884
DOI: 10.3390/s23249884

Investigation on Droplet Heat Transfer Characteristics of Continuous-Flow PCR

Jiyu Meng, He Zhang, Xiaotong Sun, Chengzhuang Yu, Xinhang Feng, Chunyang Wei, Changbin Yu and Shanshan Li

Anal. Chem., 2025, 97, 24486
DOI: 10.1021/acs.analchem.5c04157

Pre-Degassed Microfluidic Chamber-Based Digital PCR Device for Meat Authentication Applications

Hezhi Hu, Jingmeng Cheng, Chunyang Wei, Shanshan Li, Chengzhuang Yu, Xiaoshuai Meng and Junwei Li

Micromachines, 2021, 12, 694
DOI: 10.3390/mi12060694

Fused Deposition Modeling of Chemically Resistant Microfluidic Chips in Polyvinylidene Fluoride

Christof Rein, Leonhard Hambitzer, Zahra Soraya, Han Zhang, Henning J. Jessen, Frederik Kotz-Helmer and Bastian E. Rapp

Micromachines, 2024, 15, 1391
DOI: 10.3390/mi15111391

Antifouling slippery liquid infused porous surface for surfactant-free PCR on digital microfluidics platform

Neeti Kalyani, Marc Cernuda Pastor, Luca Pezzarossa, Iben Moller-Hansen, Georgi Tanev, Maria Dimaki, Irina Borodina, Jan Madsen and Winnie Edith Svendsen

Talanta, 2025, 282, 127001
DOI: 10.1016/j.talanta.2024.127001

High-fidelity, large-scale targeted profiling of microsatellites

Caitlin A. Loh, Danielle A. Shields, Adam Schwing and Gilad D. Evrony

Genome Res., 2024, 34, 1008
DOI: 10.1101/gr.278785.123

Investigation of DNA Hybridization on Nano-Structured Plasmonic Surfaces for Identifying Nasopharyngeal Viruses

Shao-Sian Li, Yi-Jung Lu, Ray Chang, Ming-Han Tsai, Jo-Ning Hung, Wei-Hung Chen, Yu-Jui Fan, Pei-Kuen Wei and Horn-Jiunn Sheen

Bioengineering, 2023, 10, 1189
DOI: 10.3390/bioengineering10101189

Dual-nozzle microfluidic droplet generator

Ji Wook Choi, Jong Min Lee, Tae Hyun Kim, Jang Ho Ha, Christian D. Ahrberg and Bong Geun Chung

Nano Convergence, 2018, 5
DOI: 10.1186/s40580-018-0145-2

Sensitive detection of microRNA using a label-free copper nanoparticle system with polymerase-based signal amplification

Jiangnan Lu, Shuping Liang, Li Tan, Kun Hu, Shulin Zhao and Jianniao Tian

Anal Bioanal Chem, 2020, 412, 7179
DOI: 10.1007/s00216-020-02850-y

Rapid and simultaneous detection of multiple pathogens in the lower reproductive tract during pregnancy based on loop-mediated isothermal amplification-microfluidic chip

Xiaofang Xu, Yiguo Jia, Ruolin Li, Yuting Wen, Yuchen Liang, Guangjie Lao, Xiaojuan Liu, Wei Zhou, Huawei Liu, Jiang Xie, Xiaoxia Wang, Wenming Xu and Qun Sun

BMC Microbiol, 2022, 22
DOI: 10.1186/s12866-022-02657-0

Present status of microfluidic PCR chip in nucleic acid detection and future perspective

Shiyu Chen, Yucheng Sun, Fangfang Fan, Shulang Chen, Yingrui Zhang, Yi Zhang, Xianli Meng and Jin-Ming Lin

TrAC Trends in Analytical Chemistry, 2022, 157, 116737
DOI: 10.1016/j.trac.2022.116737

High-throughput and uniform large field-of-view multichannel fluorescence microscopy with super-thin dichroism for a dPCR gene chip

Francis Yaw Otuboah, Jihong Zheng, Cheng Chen, Zicheng Wang, Xinjun Wan and Liujie Sun

Appl. Opt., 2020, 59, 10768
DOI: 10.1364/AO.403495

Rapid and visual detection of specific bacteria for saliva and vaginal fluid identification with the lateral flow dipstick strategy

Daijing Yu, Jun Zhang, Niu Gao, Yumei Huo, Wanting Li, Tian Wang, Xiaomeng Zhang, Halimureti Simayijiang and Jiangwei Yan

Int J Legal Med, 2023, 137, 1853
DOI: 10.1007/s00414-023-03051-9

Developing an Off-the-Shelf Microfluidic Droplet Generation Device for Cell Encapsulation

Mojtaba Hassani-Gangaraj and Amir Shamloo

Ind. Eng. Chem. Res., 2022, 61, 10689
DOI: 10.1021/acs.iecr.2c01301

Web hybrid chain reaction enhanced fluorescent magnetic bead array for digital nucleic acid detection

Furui Jin, Min Liu and Danke Xu

Talanta, 2023, 253, 123968
DOI: 10.1016/j.talanta.2022.123968

The kinetic requirements of extreme qPCR

Adam L. Millington, Jessica A. Houskeeper, John F. Quackenbush, James M. Trauba and Carl T. Wittwer

Biomolecular Detection and Quantification, 2019, 17, 100081
DOI: 10.1016/j.bdq.2019.100081

Web Hybrid Chain Reaction Enhanced Fluorescent Magnetic Bead Arrayfor Digital Nucleic Acid Detection

Furui Jin, Min Liu and Danke Xu

SSRN Journal, 2022
DOI: 10.2139/ssrn.4154906

An Integrated Micro‐Heating System for On‐Chip Isothermal Amplification of African Swine Fever Virus Genes

Jiajia Sun, Zongqian Shi, Qiongxiang Tan, Mingjie Zhong, Nan Wang, Shumin Xin, Xiaofeng Liu, Ruohan Li, Yuxin Ma, Kai Wu, Yali Cui and Wenli Hui

Small, 2024, 20
DOI: 10.1002/smll.202402446

Rapid detection of foodborne bacterial pathogens using visual high‐throughput microfluidic chip

Zengjun Jin, Guotao Ding, Guiying Li, Guoxing Yang, Yonghong Han, Ning Hao, Jian Deng, Yan Zhang, Wei Zhang and Weihao Li

J of Chemical Tech & Biotech, 2020, 95, 1460
DOI: 10.1002/jctb.6331

Stable Flexible Transparent Electrodes for Localized Heating of Lab‐on‐a‐Chip Devices

Dorina T. Papanastasiou, Abderrahime Sekkat, Viet Huong Nguyen, Carmen Jiménez, David Muñoz‐Rojas, Franz Bruckert and Daniel Bellet

Adv Materials Technologies, 2023, 8
DOI: 10.1002/admt.202200563

Evaluation of Thermal Hydraulic Characteristics of a Two Phase Superhydrophobic Microfluidic Device using Volume of Fluid Method

Umair Aziz, Muhammad Nadeem, Feng Xin, Mustafa Kilic and Atta Ullah

Nanoscale and Microscale Thermophysical Engineering, 2022, 26, 67
DOI: 10.1080/15567265.2022.2070562

Heater Integrated Lab-on-a-Chip Device for Rapid HLA Alleles Amplification towards Prevention of Drug Hypersensitivity

Shah Mukim Uddin, Abkar Sayad, Jianxiong Chan, Duc Hau Huynh, Efstratios Skafidas and Patrick Kwan

Sensors, 2021, 21, 3413
DOI: 10.3390/s21103413

Silicon Microthermocycler for Point-of-Care Analytical Systems: Modeling, Design, and Fabrication

Borut Pečar, Aljaž Zadravec, Danilo Vrtačnik and Matej Možek

Micromachines, 2024, 15, 1325
DOI: 10.3390/mi15111325

Single File Flow of Biomimetic Beads for Continuous SERS Recording in a Microfluidic Device

Diego Calzavara, Davide Ferraro, Lucio Litti, Greshia Cappozzo, Giampaolo Mistura, Moreno Meneghetti and Matteo Pierno

Advances in Condensed Matter Physics, 2018, 2018, 1
DOI: 10.1155/2018/2849175

A microfluidic-multiwell platform for rapid phase mapping of surfactant solutions

Haoyu Wang, Sepideh Khodaparast, John Carroll, Caroline Kelly, Eric S. J. Robles and João T. Cabral

Review of Scientific Instruments, 2020, 91
DOI: 10.1063/1.5144770

An Optimal Transport Medium for SARS-CoV-2 Detection in the Direct Method of Rapid Microfluidic PCR System

Miyako Takata, Masaki Nakamoto, Tsuyoshi Kitaura, Kensaku Okada, Hiroko Endou, Athok Shofiudin Ma’arif, Yukari Nishikawa, Kengo Mukuda, Shota Morishita, Hiromi Murota, Akira Yamasaki, Seiji Kageyama, Naoto Burioka and Hiroki Chikumi

Yonago Acta Med., 2024, 67, 293
DOI: 10.33160/yam.2024.11.003

Passively driven microfluidic device with simple operation in the development of nanolitre droplet assay in nucleic acid detection

Pei-Heng Lin and Bor-Ran Li

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-00470-9

An Aluminum-Based Microfluidic Chip for Polymerase Chain Reaction Diagnosis

Siyu Yang, Ziyi Zhang, Qingyue Xian, Qi Song, Yiteng Liu, Yibo Gao and Weijia Wen

Molecules, 2023, 28, 1085
DOI: 10.3390/molecules28031085

Microchip device with dry-stored reagents for Loop mediated isothermal amplification

A Tupik, G Rudnitskaya, A Bulyanitsa, T Lukashenko, D Varlamov and A Evstrapov

J. Phys.: Conf. Ser., 2018, 1124, 031015
DOI: 10.1088/1742-6596/1124/3/031015

Complete Prevention of Bubbles in a PDMS-Based Digital PCR Chip with a Multifunction Cavity

Shiyuan Gao, Tiegang Xu, Lei Wu, Xiaoyue Zhu, Xuefeng Wang, Ying Chen, Gang Li and Xinxin Li

Biosensors, 2024, 14, 114
DOI: 10.3390/bios14030114

Low-Cost, Real-Time Polymerase Chain Reaction System for Point-of-Care Medical Diagnosis

Tchamie Kadja, Chengkun Liu, Yvonne Sun and Vamsy P. Chodavarapu

Sensors, 2022, 22, 2320
DOI: 10.3390/s22062320

Multiplexed on-chip real-time PCR using hydrogel spot array for microRNA profiling of minimal tissue samples

Seungwon Jung, Bong Kyun Kim, Sangjoon Lee, Seungmin Yoon, Heh-In Im and Sang Kyung Kim

Sensors and Actuators B: Chemical, 2018, 262, 118
DOI: 10.1016/j.snb.2018.01.228

Paper-based microfluidics for rapid diagnostics and drug delivery

Kang Mao, Xiaocui Min, Hua Zhang, Kuankuan Zhang, Haorui Cao, Yongkun Guo and Zhugen Yang

Journal of Controlled Release, 2020, 322, 187
DOI: 10.1016/j.jconrel.2020.03.010

A Simple and Fast Manual Centrifuge to Spin Solutions in 96-Well PCR Plates

Ken Motohashi

MPs, 2020, 3, 41
DOI: 10.3390/mps3020041

Fabrication of a Microfluidic Flame Atomic Emission Spectrometer: a Flame-on-a-Chip

Arpad Kiss and Attila Gaspar

Anal. Chem., 2018, 90, 5995
DOI: 10.1021/acs.analchem.8b00774

Miniaturized Non-Contact Heating and Transmitted Light Imaging Using an Inexpensive and Modular 3D-Printed Platform for Molecular Diagnostics

Alex Laman, Debayan Das and Aashish Priye

Sensors, 2023, 23, 7718
DOI: 10.3390/s23187718

Flexible Particle Focusing and Switching in Continuous Flow via Controllable Thermal Buoyancy Convection

Kailiang Zhang, Yukun Ren, Likai Hou, Tianyi Jiang and Hongyuan Jiang

Anal. Chem., 2020, 92, 2778
DOI: 10.1021/acs.analchem.9b05086

Ultrafast and Real-Time Nanoplasmonic On-Chip Polymerase Chain Reaction for Rapid and Quantitative Molecular Diagnostics

Byoung-Hoon Kang, Youngseop Lee, Eun-Sil Yu, Hamin Na, Minhee Kang, Hee Jae Huh and Ki-Hun Jeong

ACS Nano, 2021, 15, 10194
DOI: 10.1021/acsnano.1c02154

Fabrication of Wearable PDMS Device for Rapid Detection of Nucleic Acids via Recombinase Polymerase Amplification Operated by Human Body Heat

Kieu The Loan Trinh and Nae Yoon Lee

Biosensors, 2022, 12, 72
DOI: 10.3390/bios12020072

A film-based integrated chip for gene amplification and electrochemical detection of pathogens causing foodborne illnesses

Yoo Min Park, Sun Young Lim, Su Jeong Shin, Chi Hyun Kim, Soon Woo Jeong, Seol Yi Shin, Nam Ho Bae, Seok Jae Lee, Jeongkyeong Na, Gyoo Yeol Jung and Tae Jae Lee

Analytica Chimica Acta, 2018, 1027, 57
DOI: 10.1016/j.aca.2018.03.061

Free convective PCR: From principle study to commercial applications—A critical review

Guijun Miao, Lulu Zhang, Jing Zhang, Shengxiang Ge, Ningshao Xia, Shizhi Qian, Duli Yu and Xianbo Qiu

Analytica Chimica Acta, 2020, 1108, 177
DOI: 10.1016/j.aca.2020.01.069

Colorimetric polymerase chain reaction mediated by pH indicator: Rapid detection of drug-resistant nosocomial bacteria

Thi Ngoc Diep Trinh, Kieu The Loan Trinh and Nae Yoon Lee

Talanta, 2025, 284, 127193
DOI: 10.1016/j.talanta.2024.127193

Microfluidics meets layer-by-layer assembly for the build-up of polymeric scaffolds

Abubakar Musa Yola, Jack Campbell and Dmitry Volodkin

Applied Surface Science Advances, 2021, 5, 100091
DOI: 10.1016/j.apsadv.2021.100091

A size reduction method for rapid digital PCR using thin-film chip and vacuum pouch microfluidic system

Cheng-Je Lee and Yu-Hsiang Hsu

Microfluid Nanofluid, 2022, 26
DOI: 10.1007/s10404-021-02507-x

Tailored Fluorosurfactants through Controlled/Living Radical Polymerization for Highly Stable Microfluidic Droplet Generation

Xiangke Li, Shi‐Yang Tang, Yang Zhang, Jiayuan Zhu, Helen Forgham, Chun‐Xia Zhao, Cheng Zhang, Thomas P. Davis and Ruirui Qiao

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202315552

Lab-on-a-Chip Technologies for the Single Cell Level: Separation, Analysis, and Diagnostics

Axel Hochstetter

Micromachines, 2020, 11, 468
DOI: 10.3390/mi11050468

Development of a method for rapid and simultaneous detection of antibiotic resistance genes in wastewater using a portable quantitative PCR device

Soichiro Hirai, Fumito Tsuzuki and Eiji Haramoto

Science of The Total Environment, 2026, 1015, 181337
DOI: 10.1016/j.scitotenv.2025.181337

Point of Care Diagnostics in the Age of COVID-19

Meysam Rezaei, Sajad Razavi Bazaz, Sareh Zhand, Nima Sayyadi, Dayong Jin, Martin P. Stewart and Majid Ebrahimi Warkiani

Diagnostics, 2020, 11, 9
DOI: 10.3390/diagnostics11010009

Implementation of the inverse problem for on-chip PCR diagnostics with rapid and precise thermal cycling

Saeed Shoaee, Iman Amani Tehrani, Fatemeh Ahmadi and Mojtaba Taghipoor

Sensors and Actuators A: Physical, 2024, 369, 115176
DOI: 10.1016/j.sna.2024.115176

Applications and perspectives on microfluidic technologies in ships and marine engineering: a review

Junsheng Wang, Myint Myint Maw, Xiaomei Yu, Bowen Dai, Ge Wang and Zong Jiang

Microfluid Nanofluid, 2017, 21
DOI: 10.1007/s10404-017-1873-z

Microfluidic Microreactor Device With Integrated Heaters for Temperature Assisted Synthesis of Gold Nanoparticles and Alkene

Tinku Naik Banavathi, Mukesh Kumar Sivakumar, Aniket Balapure, Sohan Dudala, Satish Kumar Dubey and Sanket Goel

IEEE Open J. Nanotechnol., 2024, 5, 134
DOI: 10.1109/OJNANO.2024.3492116

Simulation analysis and experimental verification of thermodynamic characteristics of integrated droplet digital PCR chip

Xiangkai Meng, Luyang Duanmu and Ping Gong

Microfluid Nanofluid, 2024, 28
DOI: 10.1007/s10404-024-02737-9

The Effect of Non-Uniform Magnetic Field on the Efficiency of Mixing in Droplet-Based Microfluidics: A Numerical Investigation

Masoud Rezaeian, Moein Nouri, Mojtaba Hassani-Gangaraj, Amir Shamloo and Rohollah Nasiri

Micromachines, 2022, 13, 1661
DOI: 10.3390/mi13101661

Microfluidic-Based Nucleic Acid Amplification Systems in Microbiology

Lena Gorgannezhad, Helen Stratton and Nam-Trung Nguyen

Micromachines, 2019, 10, 408
DOI: 10.3390/mi10060408

Raman-Based Diagnostics of Biotic and Abiotic Stresses in Plants. A Review

William Z. Payne and Dmitry Kurouski

Front. Plant Sci., 2021, 11
DOI: 10.3389/fpls.2020.616672

Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum

Wei Ouyang, Zirui Li and Jongyoon Han

Anal. Chem., 2018, 90, 11366
DOI: 10.1021/acs.analchem.8b02330

CMOS Enabled Microfluidic Systems for Healthcare Based Applications

Sherjeel M. Khan, Abdurrahman Gumus, Joanna M. Nassar and Muhammad M. Hussain

Advanced Materials, 2018, 30
DOI: 10.1002/adma.201705759

Continuous microfluidic mixing and the highly controlled nanoparticle synthesis using direct current-induced thermal buoyancy convection

Kailiang Zhang, Yukun Ren, Likai Hou, Ye Tao, Weiyu Liu, Tianyi Jiang and Hongyuan Jiang

Microfluid Nanofluid, 2020, 24
DOI: 10.1007/s10404-019-2306-y

Picoliter liquid operations in nanofluidic channel utilizing an open/close valve with nanoscale curved structure mimicking glass deflection

Hiroki Sano, Yutaka Kazoe, Kyojiro Morikawa and Takehiko Kitamori

J. Micromech. Microeng., 2022, 32, 055009
DOI: 10.1088/1361-6439/ac6204

A novel method of droplet generation based on the self-propelling of water phase and its potential application in multiplexing continuous flow PCR

Xiaoguang Lu, Qianyue Jia, Yaning Zheng, Zishan Qin, Yong Li, Chao Shi and Cuiping Ma

Biosensors and Bioelectronics, 2025, 279, 117400
DOI: 10.1016/j.bios.2025.117400

Advances of Microfluidics in Biomedical Engineering

Qifeng Zhong, Haibo Ding, Bingbing Gao, Zhenzhu He and Zhongze Gu

Adv Materials Technologies, 2019, 4
DOI: 10.1002/admt.201800663

Q3: A Compact Device for Quick, High Precision qPCR

Marco Cereda, Alessandro Cocci, Davide Cucchi, Lillo Raia, Danilo Pirola, Lorenzo Bruno, Pietro Ferrari, Valentina Pavanati, Giorgia Calisti, Francesco Ferrara, Alessandro P. Bramanti and Marco A. Bianchessi

Sensors, 2018, 18, 2583
DOI: 10.3390/s18082583

Development of a real-time RT-PCR system applicable for rapid and pen-side diagnosis of foot-and-mouth disease using a portable device, PicoGene® PCR1100

Yuto Matsui, Jeeranant Chottikamporn, Sahawatchara Ungvanijban, Kingkarn Boonsuya Seeyo, Ratchaneekorn Vitoonpong, Nutthakarn Suwankitwat, Tapanut Songkasupa, Junzo Norimine, Kentaro Yamada, Lerdchai Chintapitaksakul and Naoaki Misawa

Journal of Virological Methods, 2023, 319, 114753
DOI: 10.1016/j.jviromet.2023.114753

Advances in point-of-care genetic testing for personalized medicine applications

A. S. de Olazarra and S. X. Wang

Biomicrofluidics, 2023, 17
DOI: 10.1063/5.0143311

Negative Pressure Provides Simple and Stable Droplet Generation in a Flow-Focusing Microfluidic Device

Nikita A. Filatov, Anatoly A. Evstrapov and Anton S. Bukatin

Micromachines, 2021, 12, 662
DOI: 10.3390/mi12060662

Biosensors for rapid detection of bacterial pathogens in water, food and environment

Raphael Chukwuka Nnachi, Ning Sui, Bowen Ke, Zhenhua Luo, Nikhil Bhalla, Daping He and Zhugen Yang

Environment International, 2022, 166, 107357
DOI: 10.1016/j.envint.2022.107357

Thermal cycling characteristics of a 3D-printed serpentine microchannel for DNA amplification by polymerase chain reaction

Jaehyun Park and Heesung Park

Sensors and Actuators A: Physical, 2017, 268, 183
DOI: 10.1016/j.sna.2017.10.044

Microfluidics for Biomedical Analysis

Yong Yang, Yong Chen, Hao Tang, Nan Zong and Xingyu Jiang

Small Methods, 2020, 4
DOI: 10.1002/smtd.201900451

Rapid and simple pressure-sensitive adhesive microdevice fabrication for sequence-specific capture and fluorescence detection of sepsis-related bacterial plasmid gene sequences

Yesman Akuoko, Robert L. Hanson, David H. Harris, Jacob B. Nielsen, Elaine Lazalde and Adam T. Woolley

Anal Bioanal Chem, 2021, 413, 1017
DOI: 10.1007/s00216-020-03060-2

2D large-scale EWOD devices with honeycomb electrodes for multiplexed multidirectional driving of micro-droplets

Kaidi Zhang, Wei Wang, Chunqiao Li, Antoine Riaud and Jia Zhou

AIP Advances, 2020, 10
DOI: 10.1063/5.0008071

High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches

Huagui Zhang, Richard D Whalley, Ana Marina Ferreira and Kenneth Dalgarno

Prog. Biomed. Eng., 2020, 2, 022001
DOI: 10.1088/2516-1091/ab7cc4

An integrated droplet digital PCR gene chip for absolute quantification of nucleic acid

Xiangkai Meng, Yuanhua Yu, Ping Gong and Guangyong Jin

Microfluid Nanofluid, 2021, 25
DOI: 10.1007/s10404-021-02465-4

Integration of rolling circle amplification and optomagnetic detection on a polymer chip

Francesca Garbarino, Gabriel Antonio S. Minero, Giovanni Rizzi, Jeppe Fock and Mikkel Fougt Hansen

Biosensors and Bioelectronics, 2019, 142, 111485
DOI: 10.1016/j.bios.2019.111485

Particle detection and tracking with DNA

Ciaran A. J. O’Hare, Vassili G. Matsos, Joseph Newton, Karl Smith, Joel Hochstetter, Ravi Jaiswar, Wunna Kyaw, Aimee McNamara, Zdenka Kuncic, Sushma Nagaraja Grellscheid and Céline Bœhm

Eur. Phys. J. C, 2022, 82
DOI: 10.1140/epjc/s10052-022-10264-6

Perspectives on Multiscale Colloid-Based Materials for Biomedical Applications

Wen Li, Judah Huberman-Shlaes and Bozhi Tian

Langmuir, 2023, 39, 13759
DOI: 10.1021/acs.langmuir.3c01274

Miniaturized Thermal Monitoring Module With CO₂ Laser Ablated Microfluidic Device for Electrochemically Validated DNA Amplification

Madhusudan B. Kulkarni, Mary Salve and Sanket Goel

IEEE Trans. Instrum. Meas., 2021, 70, 1
DOI: 10.1109/TIM.2021.3097861

Development and Challenges of Pathogen Molecular Point‐Of‐Care Testing Systems Based on Microfluidic Technology

Shanshan Ren, Donglai Liu and Sihong Xu

iLABMED, 2025, 3, 21
DOI: 10.1002/ila2.70

Review of electrochemical and optical biosensors for testosterone measurement

Maryam Nikkhah, Sajedeh Karami, Seyyed Hossein Khatami, Mortaza Taheri‐Anganeh, Amir Savardashtaki, Amir Mahmoodzadeh, Zahra Shabaninejad, Omid Vakili, Pegah Mousavi, Farhad Ghanizadeh Gerayeli, Hamid Behrouj, Hassan Ghasemi and Ahmad Movahedpour

Biotech and App Biochem, 2023, 70, 318
DOI: 10.1002/bab.2354

Microfluidics add-on technologies for single-cell analysis

Mashooq Khan, Yanhui Bi, Guangyong Zhang, Fangchao Yin, Yaoshuang Xie, Ling Lin and Qiongzheng Hu

TrAC Trends in Analytical Chemistry, 2023, 167, 117257
DOI: 10.1016/j.trac.2023.117257

3D Printed Nanosensors for Cancer Diagnosis: Advances and Future Perspective

Babita Gupta, Rishabha Malviya, Saurabh Srivastava, Irfan Ahmad, Safia Obaidur Rab and Deependra Pratap Singh

CPD, 2024, 30, 2993
DOI: 10.2174/0113816128322300240725052530

Instrumentation for xPCR Incorporating qPCR and HRMA

Alexander R. Jafek, Sean Harbertson, Hayden Brady, Raheel Samuel and Bruce K. Gale

Anal. Chem., 2018, 90, 7190
DOI: 10.1021/acs.analchem.7b05176

Investigation of time-based pressure control for microfluidics chip design

Sezgin Ersoy, Gurcan ATAKOK, Danial Khorsandi and Ersin Toptaş

Journal of Engineering Research, 2023, 11, 14067
DOI: 10.36909/jer.14067

Biochip with Agarose Microcells Containing Thermally Separable Primers

A. M. Zolotov, R. A. Miftakhov, A. Y. Ikonnikova, S. A. Lapa, V. E. Kuznetsova, V. A. Vasiliskov, V. E. Shershov, A. S. Zasedatelev, T. V. Nasedkina and A. V. Chudinov

Russ J Bioorg Chem, 2022, 48, 858
DOI: 10.1134/S1068162022040203

Microfluidic Devices in the Fast‐Growing Domain of Single‐Cell Analysis

Mashooq Khan, Sifeng Mao, Weiwei Li and Jin‐Ming Lin

Chemistry A European J, 2018, 24, 15398
DOI: 10.1002/chem.201800305

Poisson statistics-mediated particle/cell counting in microwell arrays

Christian D. Ahrberg, Jong Min Lee and Bong Geun Chung

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-20913-0

Surface Engineering of a Bioartificial Membrane for Its Application in Bioengineering Devices

Pragyan Ray, Ruchira Chakraborty, Oindrila Banik, Earu Banoth and Prasoon Kumar

ACS Omega, 2023, 8, 3606
DOI: 10.1021/acsomega.2c05983

Fabrication of a polycarbonate microdevice and boronic acid-mediated surface modification for on-chip sample purification and amplification of foodborne pathogens

Hoang Chau La and Nae Yoon Lee

Biomed Microdevices, 2019, 21
DOI: 10.1007/s10544-019-0420-y

Advancements in Airborne Viral Nucleic Acid Detection with Wearable Devices

Ryan Godin, Sepehr Hejazi and Nigel F. Reuel

Advanced Sensor Research, 2024, 3
DOI: 10.1002/adsr.202300061

Microfluidic Extreme PCR: <1 Minute DNA Amplification in a Thin Film Disposable

James M. Trauba and Carl T. Wittwer

JBiSE, 2017, 10, 219
DOI: 10.4236/jbise.2017.105017

Mobile Technologies for the Discovery, Analysis, and Engineering of the Global Microbiome

Zachary S. Ballard, Calvin Brown and Aydogan Ozcan

ACS Nano, 2018, 12, 3065
DOI: 10.1021/acsnano.7b08660

Continuous gradient temperature control of microfluidic chip based on thermoelectric cooler

Zhilin Liu, Dongfang Sun, Bin Jiang, Limei Shen, Pei Zhou, Cai Gao, Zunlong Jin, Xiangnong Liu, Lei Yang and Shiyao Tan

Applied Thermal Engineering, 2023, 234, 121277
DOI: 10.1016/j.applthermaleng.2023.121277

A flexible format LAMP assay for rapid detection of Ebola virus

Laura C. Bonney, Robert J. Watson, Gillian S. Slack, Andrew Bosworth, Nadina I. Vasileva Wand, Roger Hewson and Alyssa E. Barry

PLoS Negl Trop Dis, 2020, 14, e0008496
DOI: 10.1371/journal.pntd.0008496

Coupling Miniaturized Free-Flow Electrophoresis to Mass Spectrometry via a Multi-Emitter ESI Interface

Matthias Jender, Stefan Höving, Pedro Novo, Erik Freier and Dirk Janasek

Anal. Chem., 2021, 93, 7204
DOI: 10.1021/acs.analchem.1c00200

Features of a Non-Detachable Adhesive Bonding of Parts of Microfluid Devices from Polymethyl Methacrylate

T. A. Lukashenko, A. N. Zubik, A. L. Bulyanitsa and A. A. Evstrapov

Polym. Sci. Ser. D, 2021, 14, 222
DOI: 10.1134/S1995421221020155

Propagative-rhythmic membrane contraction modulated efficient micropumping of non-Newtonian fluids

Jaikishan Mansukhani, Arijeet Tripathy, Mahesh Kumar and Pranab Kumar Mondal

Physics of Fluids, 2022, 34
DOI: 10.1063/5.0121704

3D printed microfluidic device for combined thermal and fluorescence analysis

Derek Sanchez, Robert Macdonald, Brendan Mitchell, Marshall Rawlins, Jansen Engelbrecht, Gregory P. Nordin, Adam T. Woolley and Troy R. Munro

Microfluid Nanofluid, 2025, 29
DOI: 10.1007/s10404-025-02851-2

The achievements of clinical chemistry testing: 1967–2017

Joris R Delanghe

Clinical Biochemistry, 2017, 50, 165
DOI: 10.1016/j.clinbiochem.2016.11.020

Closed-Loop Microreactor on PCB for Ultra-Fast DNA Amplification: Design and Thermal Validation

Panagiotis Skaltsounis, George Kokkoris, Theodoros G. Papaioannou and Angeliki Tserepi

Micromachines, 2023, 14, 172
DOI: 10.3390/mi14010172

A Disposable and Multi-Chamber Film-Based PCR Chip for Detection of Foodborne Pathogen

Nam Ho Bae, Sun Young Lim, Younseong Song, Soon Woo Jeong, Seol Yi Shin, Yong Tae Kim, Tae Jae Lee, Kyoung G. Lee, Seok Jae Lee, Yong-Jun Oh and Yoo Min Park

Sensors, 2018, 18, 3158
DOI: 10.3390/s18093158

Multichamber hybrid microfluidic chips for nucleic acids detection by qPCR assay

P Afonicheva, A Zubik, A Bulyanitsa, G Rudnitskaya and A Evstrapov

J. Phys.: Conf. Ser., 2020, 1695, 012060
DOI: 10.1088/1742-6596/1695/1/012060

Nucleic Acid Tests for Clinical Translation

Min Li, Fangfei Yin, Lu Song, Xiuhai Mao, Fan Li, Chunhai Fan, Xiaolei Zuo and Qiang Xia

Chem. Rev., 2021, 121, 10469
DOI: 10.1021/acs.chemrev.1c00241