Issue 7, 2019

Photoinduced decarboxylative azidation of cyclic amino acids

Abstract

The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

Graphical abstract: Photoinduced decarboxylative azidation of cyclic amino acids

Supplementary files

Article information

Article type
Communication
Submitted
31 Nhl 2018
Accepted
13 N’w 2018
First published
26 N’w 2018

Org. Biomol. Chem., 2019,17, 1839-1842

Photoinduced decarboxylative azidation of cyclic amino acids

D. C. Marcote, R. Street-Jeakings, E. Dauncey, J. J. Douglas, A. Ruffoni and D. Leonori, Org. Biomol. Chem., 2019, 17, 1839 DOI: 10.1039/C8OB02702A

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