Issue 22, 2012
From the journal:

RSC Advances

Highly fluorescent benzofuran derivatives of the GFP chromophore†

Mikkel Andreas Christensen,a   Karsten Jennum,a   Peter Bæch Abrahamsen,a   Eduardo Antonio Della Pia,a   Kasper Lincke,a   Søren Lindbæk Broman,a   David Bo Nygaard,a   Andrew D. Bondb  and  Mogens Brøndsted Nielsen*a  

* Corresponding authors

a Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen Ø, Denmark
E-mail: mbn@kiku.dk
Fax: +45 3532 0212
Tel: +45 3532 0210

b Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

Abstract

Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.

Graphical abstract: Highly fluorescent benzofuran derivatives of the GFP chromophore

  • This article is part of the themed collection: Aromaticity
About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2RA21380J
Article type
Communication
Submitted
06 Maw 2012
Accepted
11 Maw 2012
First published
13 Maw 2012

RSC Adv., 2012,2, 8243-8249

Permissions

Request permissions

Highly fluorescent benzofuran derivatives of the GFP chromophore

M. A. Christensen, K. Jennum, P. B. Abrahamsen, E. A. D. Pia, K. Lincke, S. L. Broman, D. B. Nygaard, A. D. Bond and M. B. Nielsen, RSC Adv., 2012, 2, 8243 DOI: 10.1039/C2RA21380J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements