How octopod Mn–Fe oxide nanoparticle tracers minimize relaxation time and enhance MPI resolution

Abstract

Achieving high spatial resolution in magnetic particle imaging (MPI) remains a major challenge in advancing MPI capabilities. In this study, Mn–Fe oxide nanoparticle tracers with octopod morphology were synthesized, showing a 2.3-fold improvement in spatial resolution while maintaining strong signal intensity at higher tracer concentrations. This approach enables high-resolution MPI by minimizing relaxation time through controlled anisotropy.