Issue 21, 2024

A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine

Abstract

Hydrogen sulfide (H2S) and hydrazine (N2H4) are toxic compounds in environmental and living systems, and hydrogen sulfide is also an important signaling molecule. However, in the absence of dual-color probes capable of detecting both H2S and N2H4, the ability to monitor the crosstalk of these substances is restricted. Herein, we developed an ESIPT-based dual-response fluorescent probe (BDM-DNP) for H2S and N2H4 detection via dually responsive sites. The BDM-DNP possessed absorbing strength in the detection of H2S and N2H4, with a large Stokes shift (156 nm for H2S and 108 nm for N2H4), high selectivity and sensitivity, and good biocompatibility. Furthermore, BDM-DNP can be utilized for the detection of hydrogen sulfide and hydrazine in actual soil, and gaseous H2S and N2H4 in environmental systems. Notably, BDM-DNP can detect H2S and N2H4 in living cells for disease diagnosis and treatment evaluation.

Graphical abstract: A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine

Supplementary files

Article information

Article type
Paper
Submitted
16 Yan 2024
Accepted
04 Mud 2024
First published
07 Mud 2024

J. Mater. Chem. B, 2024,12, 5150-5156

A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine

Q. Gong, Y. Lai and W. Lin, J. Mater. Chem. B, 2024, 12, 5150 DOI: 10.1039/D4TB00318G

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