Issue 71, 2024

A near-infrared light-driven Janus nanomotor for deep tumor penetration and enhanced tumor immunotherapy

Abstract

A near-infrared light-driven Janus nanomotor is constructed by collagenase-coated gold nanorods and chitosan-functionalized mesoporous organosilica nanoparticles with Mn2+ as the bridging ion. The nanomotors with excellent motility and collagenase activity can potently penetrate into tumors to sufficiently activate innate immune responses, significantly enhancing anti-tumor immune efficacy in vivo.

Graphical abstract: A near-infrared light-driven Janus nanomotor for deep tumor penetration and enhanced tumor immunotherapy

Supplementary files

Article information

Article type
Communication
Submitted
10 Maw 2024
Accepted
30 Maw 2024
First published
01 Mha 2024

Chem. Commun., 2024,60, 9550-9553

A near-infrared light-driven Janus nanomotor for deep tumor penetration and enhanced tumor immunotherapy

K. Ma, Z. Chen, K. Liang, Y. Pei and Z. Pei, Chem. Commun., 2024, 60, 9550 DOI: 10.1039/D4CC03445G

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