Issue 10, 2024

Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

Abstract

We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.

Graphical abstract: Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

Supplementary files

Article information

Article type
Communication
Submitted
07 Ndz 2023
Accepted
18 N’w 2023
First published
27 N’w 2023
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2024,60, 1305-1308

Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

C. Heuer, X. Jiang, G. Ron, O. Ternyak, T. Scheper, J. Bahnemann and E. Segal, Chem. Commun., 2024, 60, 1305 DOI: 10.1039/D3CC04446G

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