Issue 47, 2023

Polymeric engineering of AIEgens for NIR-II fluorescence imaging and detection of abdominal metastases of ovarian cancer in vivo

Abstract

A polymeric engineering design principle is proposed for the construction of small-sized (∼20 nm) NIR-II AIEgen-doped nanodots (AIEdots) with high brightness and prolonged circulation time in blood vessels. With the utilization of the as-designed NIR-II AIEdots, the successful achievement of high-resolution NIR-II fluorescence imaging of tumor vessels and precise detection of abdominal metastases of ovarian cancer has been attained.

Graphical abstract: Polymeric engineering of AIEgens for NIR-II fluorescence imaging and detection of abdominal metastases of ovarian cancer in vivo

Supplementary files

Article information

Article type
Communication
Submitted
03 Mha 2023
Accepted
07 Nhl 2023
First published
10 Nhl 2023

J. Mater. Chem. B, 2023,11, 11217-11221

Polymeric engineering of AIEgens for NIR-II fluorescence imaging and detection of abdominal metastases of ovarian cancer in vivo

X. Zhou, Y. Zeng, S. Li, K. Zhang, L. Zhao, G. Li, Q. Wang, H. Ji, M. Wu, J. Liu, Y. Qin, W. Feng, F. Li and L. Wu, J. Mater. Chem. B, 2023, 11, 11217 DOI: 10.1039/D3TB01750H

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