Issue 63, 2021

Organelle-targeted photothermal agents for cancer therapy

Abstract

Over the past ten years, advances in the field of organelle-targeted photothermal therapy (PTT) have stimulated the rapid development of organelle-targeted PTT agents as anticancer therapeutic agents. However, to the best of our knowledge, no comprehensive review of organelle-targeted PTT agents has been reported thus far. In this article, we have provided a structured approach for describing the different types and properties of each organelle-targeted PTT agent as well as the potential future therapeutic applications that were classified by their target organelles. Representative agents that have been used in the field of PTT since 2010 have been summarized and the most recent advances in improving the therapeutic efficacy across various types of cancers have also been highlighted.

Graphical abstract: Organelle-targeted photothermal agents for cancer therapy

Supplementary files

Article information

Article type
Feature Article
Submitted
23 Dzi 2021
Accepted
21 Kho 2021
First published
22 Kho 2021

Chem. Commun., 2021,57, 7731-7742

Organelle-targeted photothermal agents for cancer therapy

E. Hwang and H. S. Jung, Chem. Commun., 2021, 57, 7731 DOI: 10.1039/D1CC02168K

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