Issue 4, 2020

Recent progress in supramolecular peptide assemblies as virus mimics for cancer immunotherapy

Abstract

Immunotherapy has revolutionized the field of cancer therapy. Nanomaterials can further improve the efficacy and safety of immunotherapy because of their tunability and multifunctionality. A supramolecular peptide assembly (SPA), as a close mimic of natural viruses, is a unique type of nanomaterial with high epitope valency, multifunctionality and biocompatibility. Given its great potential in cancer immunotherapy, especially in cancer vaccines, in the current review, we summarize the unique features of the SPA that are beneficial for cancer immunotherapy, and highlight the important progress in using SPAs as nanoscale carriers, antigens, adjuvants or multifunctional platforms. The current challenges faced by these SPAs are also briefly discussed.

Graphical abstract: Recent progress in supramolecular peptide assemblies as virus mimics for cancer immunotherapy

Article information

Article type
Review Article
Submitted
29 Mha 2019
Accepted
08 Nhl 2019
First published
08 Nhl 2019

Biomater. Sci., 2020,8, 1045-1057

Recent progress in supramolecular peptide assemblies as virus mimics for cancer immunotherapy

Y. Cai, W. Ran, Y. Zhai, J. Wang, C. Zheng, Y. Li and P. Zhang, Biomater. Sci., 2020, 8, 1045 DOI: 10.1039/C9BM01380F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements